Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Bin Xiao"'
Autor:
Hidayat Lokman, Huck-Hui Ng, Audrey Tze Ting Khoo, Wei-Yi Ong, Junghyun Jo, Grace Lim, Hoang Dai Tran, Seung-Jae Lee, Weonjin Yu, Lin Yang, Lai Ping Yaw, Ya Yin Chang, Jessica Jiaxin Xie, Kah-Leong Lim, Bin Xiao, Eng-King Tan, Tzuen Yih Saw, Byung Chul Jung, Alfred Xuyang Sun, Hyunsoo Shawn Je
Publikováno v:
Annals of neurology. 90(3)
Objective: We utilized human midbrain-like organoids (hMLOs) generated from human pluripotent stem cells carrying glucocerebrosidase gene (GBA1) and α-synuclein (α-syn; SNCA) perturbations to investigate genotype-to-phenotype relationships in Parki
Autor:
Jing Su, Xiao-Ying Ji, Yina Wang, Bin Xiao, Xudong Xiang, Shaokun Liu, Guyi Wang, Haiyun Dong, Xianghong Yan, Su-bo Gong
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Mediators of Inflammation
Mediators of Inflammation
Background and Purpose. Allergic asthma, a respiratory disease with high morbidity and mortality, is reported to be related to the airway allergic inflammation and autophagy-induced oxidative stress. Although the therapeutic effects of fermentate pre
Autor:
Wen Jiang, Jingjing Tan, Xiao Hao, Weimin Wang, Yongjun Zhang, Zhiyu Fang, Ge Wang, Aoxue Lu, Bin Xiao, Jia Li
Publikováno v:
Journal of food biochemistryREFERENCES. 45(3)
Our previous study has optimized the acid hydrolysis process of pumpkin polysaccharides (PPe) with scavenging ability based on central composite design. The aim of this study was to explore the in vivo-antioxidant ability of PPe and pumpkin polysacch
Autor:
Yong Xu, Bin Xiao, Tianfa Li, Zilong Li, Xiaocen Kong, Yuanyuan Zhang, Yangxi Zhang, Liming Yu
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Endothelial cell derived angiocrine factors contribute to the disruption of homeostasis and the pathogenesis of cardiovascular diseases in response to stress stimuli. In the present study we investigated the role of BRG1, a key component of the chrom
Publikováno v:
Chinese Journal of Dermatology. 52
After binding to the specific insulin-like growth factor 1 receptor (IGF1R) on the surface of target tissue cells, IGF can regulate physiological processes such as apoptosis, proliferation and senescence, which are closely related to growth and devel
Publikováno v:
Cell Death and Disease, Vol 9, Iss 5, Pp 1-14 (2018)
Cell Death & Disease
Cell Death & Disease
Focal segmental glomerulosclerosis (FSGS) is a frequent glomerular disease, and is the common cause of nephrotic syndrome. However, there is no validated diagnostic blood biomarker for FSGS. Here, we performed a real-time PCR-based high-throughput mi
Publikováno v:
Skeletal Muscle
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Skeletal Muscle, Vol 9, Iss 1, Pp 1-16 (2019)
Background Growth differentiation factor 11 (GDF11) is a member of the transforming growth factor β superfamily. The GDF11 propeptide, which is derived from the GDF11 precursor protein, blocks the activity of GDF11 and its homolog, myostatin, which
Autor:
Ze‑Zhou Feng, Zhao Jian, Peng Liu, Ying‑Bin Xiao, Wei‑Kun Jia, Yun Zhu, Liang Zhao, Jingwei Li, Si‑Yi He
Publikováno v:
Molecular Medicine Reports. 12:6903-6910
MicroRNAs (miRs) regulate a number of physiological and pathological processes, including myocardial chronic hypoxia. Previous studies revealed that the expression of miR-146b is increased in vitro and in vivo following the induction of hypoxia. In t
Publikováno v:
Journal of molecular medicine (Berlin, Germany). 96(7)
The cystic fibrosis transmembrane conductance regulator (CFTR) is linked to cell apoptosis and abundantly expressed in brain tissue. Mitochondrial oxidative stress plays a key role in activating apoptotic pathway following cerebral ischemia reperfusi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
To study the relationship between chromatin condensation, gene transcription and developmental competence during oocyte maturation and to explore the mechanisms by which meiotic arrest maintenance (MAM) and sexual maturity improve oocyte competence,