Zobrazeno 1 - 10
of 2 493
pro vyhledávání: ''
Autor:
Lorinda Simms, Shehkar Patil, David R. Gandara, Anders Mellemgaard, Raghunadharao Digumarti, Bonne Biesma, Johan Vansteenkiste, Mauro Zukin, Joachim von Pawel, Katherine P. Sugarman, Keunchil Park, Christian Manegold, Filippo de Marinis, Tuncay Göksel, Janusz Rolski, Piotr Serwatowski, Jin S. Lee, Giorgio V. Scagliotti, Ulrich Gatzemeier, Purvish M. Parikh
Publikováno v:
Journal of Clinical Oncology. 41:2458-2466
PURPOSE Cisplatin plus gemcitabine is a standard regimen for first-line treatment of advanced non–small-cell lung cancer (NSCLC). Phase II studies of pemetrexed plus platinum compounds have also shown activity in this setting. PATIENTS AND METHODS
Autor:
Ulrich Gatzemeier, Michael Boyer, Paolo Paoletti, Salih Emri, Christian Manegold, Claude Denham, Nicholas J. Vogelzang, James J. Rusthoven, James T. Symanowski, Clet Niyikiza, E. Kaukel, Pierre Ruffié
Publikováno v:
Journal of Clinical Oncology. 41:2125-2133
PURPOSE Patients with malignant pleural mesothelioma, a rapidly progressing malignancy with a median survival time of 6 to 9 months, have previously responded poorly to chemotherapy. We conducted a phase III trial to determine whether treatment with
Autor:
Hyung-Don Kim, Hyehyun Jeong, Jae-Lyun Lee, Kye Jin Park, J.H. Kim, Bumsik Hong, Yongjune Lee, Shinkyo Yoon
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose This study aims to evaluate the prognosis of pathologically node-positive bladder cancer after neoadjuvant chemotherapy, the role of adjuvant chemotherapy in these patients, and the value of preoperative clinical evaluation for lymph node met
Autor:
Rajneesh Kumar Singh, Koipillai Joseph Maria Das, Shagun Misra, Shaleen Kumar, Shalini Singh, Susheel Kumar Yeshala, Senthil Kumar
Publikováno v:
American Journal of Clinical Oncology. 44:475-481
OBJECTIVES The standard of care for resectable gastric cancers (GCs) includes perioperative chemotherapy (CT) or postoperative chemo/chemoradiotherapy (CRT) strategies. Poor treatment compliance postsurgery suggests that intensified surgical adjuvant
Autor:
Yungan Tao, Anne Aupérin, Xushan Sun, Christian Sire, Laurent Martin, Alexandre Coutte, Cedrik Lafond, Jessica Miroir, Xavier Liem, Frederic Rolland, Caroline Even, France Nguyen, Esma Saada, Aline Maillard, Natacha Colin-Batailhou, Juliette Thariat, Joël Guigay, Jean Bourhis
Publikováno v:
European Journal of Cancer. 141:21-29
Background Based on the hypothesis of synergistic effect of avelumab with cetuximab and radiotherapy, this new combination is tested in a randomised trial against two well-established standard of care (SOC) in locally advanced squamous-cell carcinoma
Autor:
Koji Okuda, Hisamune Sakai, Toru Hisaka, Yoshito Akagi, Katsuaki Takagi, Yuichi Goto, Shogo Fukutomi
Publikováno v:
Anticancer Research. 40:4773-4777
BACKGROUND/AIM Recent studies have demonstrated the efficacy of salvage surgery following downstaging of hepatocellular carcinoma (HCC). The aim was to assess the outcomes of salvage surgery after successful downstaging using hepatic arterial infusio
Publikováno v:
Anticancer Research. 40:1481-1486
Background/aim Peritoneal carcinomatosis is a sign of advanced ovarian cancer. If cytoreductive surgery results in a tumor-free situation with the remaining tumor being less than 0.25 cm, Hyperthermic intraperitoneal chemotherapy (HIPEC) may further
Autor:
Steven G. Rozen, Heike I. Grabsch, Alvin Wei Tian Ng, William H. Allum, Wen Fong Ooi, Jimmy Bok Yan So, Wei Peng Yong, Patrick Tan, Ruth E Langley, Raghav Sundar, Vivien Koh, Ming Hui Lee, Lindsay C. Hewitt, David Cunningham, Matthew Nankivell, Nisha Padmanabhan, Taotao Sheng, Shenli Zhang, Aditi Qamra, Hermioni Zouridis, Imran Inam
Publikováno v:
European Journal of Cancer, 123, 48-57. ELSEVIER SCI LTD
Background: DNA methylation signatures describing distinct histological subtypes of oesophageal cancer have been reported. We studied DNA methylation in samples from the MRC OE02 phase III trial, which randomised patients with resectable oesophageal
Autor:
Takahiro Watakabe, R. Toya, Yoshiyuki Fukugawa, Natsuo Oya, Daizo Murakami, Tomohiko Matsuyama, Kohei Nishimoto, Yorihisa Orita, Tetsuo Saito
Background Reports on the treatment results of chemoradiotherapy (CRT) for T3 N0 glottic carcinoma without vocal cord fixation are limited. We retrospectively evaluated the efficacy and toxicity of concurrent chemoradiotherapy (CCRT) with docetaxel,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe51a7cb730e9b49a18513c9213a391
https://doi.org/10.21203/rs.3.rs-795243/v1
https://doi.org/10.21203/rs.3.rs-795243/v1
Inhibition of autophagy by chloroquine makes chemotherapy in nasopharyngeal carcinoma more efficient
Autor:
Makiko Moriyama-Kita, Tomokazu Yoshizaki, Tomomi Aga, Akira Tsuji, Naohiro Wakisaka, Kazuhira Endo, Yosuke Nakanishi, Hisashi Sugimoto, Miyako Hatano, Satoru Kondo, Mitsuharu Aga, Takayoshi Ueno
Publikováno v:
Auris Nasus Larynx. 46:443-450
Objectives A combination of platinum-based chemotherapy and radiotherapy is the standard treatment for nasopharyngeal carcinoma (NPC). However, the efficacy of chemotherapy has reached a plateau. Many autophagy studies suggest that autophagy can eith