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Autor:
Ulrich Gatzemeier, Michael Boyer, Paolo Paoletti, Salih Emri, Christian Manegold, Claude Denham, Nicholas J. Vogelzang, James J. Rusthoven, James T. Symanowski, Clet Niyikiza, E. Kaukel, Pierre Ruffié
Publikováno v:
Journal of Clinical Oncology. 41:2125-2133
PURPOSE Patients with malignant pleural mesothelioma, a rapidly progressing malignancy with a median survival time of 6 to 9 months, have previously responded poorly to chemotherapy. We conducted a phase III trial to determine whether treatment with
Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Bryan T. Hennessy, Massimo Cristofanilli, Chafika Mazouni, Fabrice Andre, Attila Tordai, W. Fraser Symmans, Cornelia Liedtke, Marjorie C. Green, Ana M. Gonzalez-Angulo, Kenneth R. Hess, Jaime A. Mejia
Publikováno v:
Journal of Clinical Oncology. 41:1809-1815
PURPOSE Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. In this study, we compared response to neoadjuvant chemotherap
Autor:
Shota, Ike, Masatake, Matsuoka, Tomohiro, Onodera, Isao, Yokota, Koji, Iwasaki, Ryosuke, Hishimura, Yuki, Suzuki, Eiji, Kondo, Norimasa, Iwasaki
Publikováno v:
Anticancer Research. 42:1635-1640
Primary malignant osseous neoplasms of the hand are rare malignancies. Comprehensive demographic and survival data regarding primary malignant osseous neoplasms of the hand are lacking in the literature.Using the Surveillance, Epidemiology, and End R
Publikováno v:
International Journal of Cancer. 150:1760-1769
Our study measures the impact of diagnosing cancers early before they metastasise on reducing the burden of cancer death. A cohort of 716 501 people aged 15 to 89 years diagnosed with a solid cancer in New South Wales, Australia, during 1985 to 2014
Autor:
Ruiyang Zou, Sau Yeen Loke, Yew Chung Tang, Heng-Phon Too, Lihan Zhou, Ann S. G. Lee, Mikael Hartman
Publikováno v:
British Journal of Cancer. 126:472-481
Background Mammography is widely used for breast cancer screening but suffers from a high false-positive rate. Here, we perform the largest comprehensive, multi-center study to date involving diverse ethnic groups, for the identification of circulati
Autor:
Yu-Zhong Yu, Dao-Jun Lv, Chong Wang, Xian-Lu Song, Tao Xie, Tao Wang, Zhi-Min Li, Jia-Ding Guo, Du-Jiang Fu, Kang-Jin Li, Ding-Lan Wu, Franky Leung Chan, Ning-Han Feng, Zhe-Sheng Chen, Shan-Chao Zhao
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-21 (2022)
Molecular Cancer
Molecular Cancer
Background More and more studies have shown that circular RNAs (circRNAs) play a critical regulatory role in many cancers. However, the potential molecular mechanism of circRNAs in prostate cancer (PCa) remains largely unknown. Methods Differentially
Autor:
Antonino Ditto, Loris De Cecco, Biagio Paolini, Paola Alberti, Fabio Martinelli, Umberto Leone Roberti Maggiore, Giorgio Bogani, Paolo Chiodini, Sandro Pignata, Antonella Tomassetti, Francesco Raspagliesi, Delia Mezzanzanica, Marina Bagnoli
Publikováno v:
European Journal of Cancer. 161:55-63
Aim: Early-stage epithelial ovarian cancer (eEOC) patients have a generally favorable prognosis but unpredictable recurrence. Accurate prediction of risk of relapse is still a major concern, essentially to avoid overtreatment. Our robust tissue-based
Autor:
Meryem El Azzouzi, Hajar El Ahanidi, Chaimae Hafidi Alaoui, Imane Chaoui, Laila Benbacer, Mohamed Tetou, Ilias Hassan, Mounia Bensaid, Mohamed Oukabli, Ahmed Ameur, Abderrahmane Al Bouzidi, Mohammed El Mzibri, Mohammed Attaleb
Publikováno v:
Cancer Genetics. :41-45
Promoter hypermethylation have been reported to play a key role in bladder cancer development and progression. The aim of this study is to evaluate the methylation status of hTERT, TWIST1, VIM and NID2 genes in bladder cancer. The methylation status
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 112:40-51
The omission of radiation therapy (RT) in older women with stage 1 estrogen-receptor-positive (ER+) breast cancer receiving endocrine therapy (ET) is an acceptable strategy based on randomized trial data. Less is known about the omission of ET with o
Autor:
Yan Yuan, Zhifan Zeng, Rong-Zhen Li, Weiwei Xiao, Hui Chang, Qiaoxuan Wang, Yuanhong Gao, Wei-Hao Xie
Publikováno v:
Cancer Medicine, Vol 11, Iss 1, Pp 117-127 (2022)
Cancer Medicine
Cancer Medicine
Background Anal squamous cell carcinoma (ASCC) is a rare malignant tumor with increasing incidence. The goal of our study was to analyze the treatment outcome and prognostic factors of ASCC in South China in the past half‐century. Methods This stud