Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Pavel Vodicka"'
Autor:
Andrew Collins, Mirta Milić, Cristian Del Bo, Elisa Boutet-Robinet, Lisa Giovannelli, Amaya Azqueta, Stefano Bonassi, Gunnar Brunborg, Sabine A. S. Langie, Monika Sramkova, Matjaz Novak, Solange Costa, Alena Gábelová, Goran Gajski, Helga Stopper, Roger W. L. Godschalk, Maria Dusinska, Bojana Zegura, Elke Richling, Marcus S. Cooke, Sona Vodenkova, Kristine B. Gutzkow, Vanessa Moraes de Andrade, Cristiana Pereira, Nurşen Başaran, Blanca Laffon, João Paulo Teixeira, Peter Møller, Gudrun Koppen, Pavel Vodicka, Vanessa Valdiglesias
Publikováno v:
Nature Protocols
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
Møller, P, Azqueta, A, Boutet-Robinet, E, Koppen, G, Bonassi, S, Milić, M, Gajski, G, Costa, S, Teixeira, J P, Costa Pereira, C, Dusinska, M, Godschalk, R, Brunborg, G, Gutzkow, K B, Giovannelli, L, Cooke, M S, Richling, E, Laffon, B, Valdiglesias, V, Basaran, N, Del Bo’, C, Zegura, B, Novak, M, Stopper, H, Vodicka, P, Vodenkova, S, de Andrade, V M, Sramkova, M, Gabelova, A, Collins, A & Langie, S A S 2020, ' Minimum Information for Reporting on the Comet Assay (MIRCA) : recommendations for describing comet assay procedures and results ', Nature Protocols, vol. 15, pp. 3817-3826 . https://doi.org/10.1038/s41596-020-0398-1
Nature Protocols, Nature Publishing Group, 2020, ⟨10.1038/s41596-020-0398-1⟩
Nature Protocols, 15(12), 3817-3826. Nature Publishing Group
RUC. Repositorio da Universidade da Coruña
instname
RUC: Repositorio da Universidade da Coruña
Universidade da Coruña (UDC)
Møller, P, Azqueta, A, Boutet-Robinet, E, Koppen, G, Bonassi, S, Milić, M, Gajski, G, Costa, S, Teixeira, J P, Costa Pereira, C, Dusinska, M, Godschalk, R, Brunborg, G, Gutzkow, K B, Giovannelli, L, Cooke, M S, Richling, E, Laffon, B, Valdiglesias, V, Basaran, N, Del Bo’, C, Zegura, B, Novak, M, Stopper, H, Vodicka, P, Vodenkova, S, de Andrade, V M, Sramkova, M, Gabelova, A, Collins, A & Langie, S A S 2020, ' Minimum Information for Reporting on the Comet Assay (MIRCA) : recommendations for describing comet assay procedures and results ', Nature Protocols, vol. 15, pp. 3817-3826 . https://doi.org/10.1038/s41596-020-0398-1
Nature Protocols, Nature Publishing Group, 2020, ⟨10.1038/s41596-020-0398-1⟩
Nature Protocols, 15(12), 3817-3826. Nature Publishing Group
RUC. Repositorio da Universidade da Coruña
instname
The comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of baseline and induced damage in the same experimental systems. These differences may be att
Autor:
Ludmila Vodickova, Andrea Cumova, Sivaramakrishna Rachakonda, Pavel Soucek, Rajesh Kumar, Sona Vodenkova, Michal Kroupa, Andrea Rossnerova, Kari Hemminki, Vaclav Liska, Veronika Vymetalkova, Kristyna Tomasova, Pavel Vodicka
Publikováno v:
Mutagenesis. 35:491-497
Disruption of telomere length (TL) homeostasis in peripheral blood lymphocytes has been previously assessed as a potential biomarker of breast cancer (BC) risk. The present study addressed the relationship between lymphocyte TL (LTL), prognosis and c
Telomere maintenance in interplay with DNA repair in pathogenesis and treatment of colorectal cancer
Publikováno v:
Mutagenesis. 35:261-271
Colorectal cancer (CRC) continues to be one of the leading malignancies and causes of tumour-related deaths worldwide. Both impaired DNA repair mechanisms and disrupted telomere length homeostasis represent key culprits in CRC initiation, progression
Autor:
Ludmila Vodickova, Veronika Vymetalkova, Miguel Inacio da Silva Filho, Asta Försti, Christoph Frank, Katerina Jiraskova, Calogerina Catalano, Alessio Naccarati, Vaclav Liska, Miroslav Levy, Pavel Vodicka, Shun Lu, Alexander N.R. Weber, Kari Hemminki, Ondrej Vycital
Publikováno v:
Cancer Medicine, Vol 9, Iss 4, Pp 1473-1484 (2020)
Cancer Medicine
Cancer Medicine
Objective The TLR3/cGAS‐STING‐IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in thes
Autor:
Jirong Long, Anna H. Wu, Min-Ho Shin, Tabitha A. Harrison, Kenneth Offit, Ulrike Peters, Yoon-Ok Ahn, Fränzel J.B. Van Duijnhoven, Jochen Hampe, Qiuyin Cai, Stephanie J. Weinstein, Annika Lindblom, Zhi Zhong Pan, Keum Ji Jung, Chizu Tanikawa, Wanqing Wen, Andrew T. Chan, Wei Hua Jia, Yu-Tang Gao, Isao Oze, Keitaro Matsuo, Zefang Ren, Sun-Seog Kweon, Paul D.P. Pharoah, Victor Moreno, Pavel Vodicka, Yong-Bing Xiang, Jeroen R. Huyghe, Aesun Shin, Dong Hyun Kim, Sun Ha Jee, Koichi Matsuda, Jae Hwan Oh, Andrea Gsur, Yi Xin Zeng, Yingchang Lu, Nan Wang, Jiajun Shi, Wei Zheng, Bethany Van Guelpen, Loic Le Marchand, Li Li, Honglan Li, Jeongseon Kim, Alicja Wolk, Xingyi Guo, Polly A. Newcomb, Yoichiro Kamatani, Li Hsu, Jing Gao, Xiao-Ou Shu, Bingshan Li
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Cancer Epidemiology Biomarkers & Prevention 29 (2020) 2
Dipòsit Digital de la UB
Universidad de Barcelona
Cancer Epidemiology Biomarkers & Prevention, 29(2), 477-486
Cancer Epidemiology Biomarkers & Prevention 29 (2020) 2
Dipòsit Digital de la UB
Universidad de Barcelona
Cancer Epidemiology Biomarkers & Prevention, 29(2), 477-486
Background: Risk variants identified so far for colorectal cancer explain only a small proportion of familial risk of this cancer, particularly in Asians. Methods: We performed a genome-wide association study (GWAS) of colorectal cancer in East Asian
Autor:
Simona Susova, Linda Bartu, Jan Kral, Pavel Soucek, Rajesh Kumar, Ludmila Vodickova, Miroslav Levy, Tomas Buchler, Fabio Rosa, Petra Bendova, Veronika Vymetalkova, Pavel Vodicka, David J. Hughes, Alessio Naccarati, Barbara Pardini
Publikováno v:
Mutagenesis. 35:273-281
The chemotherapeutic efficacy in colorectal cancer (CRC) is limited due to the inter-individual variability in drug response and the development of tumour resistance. ATP-binding cassette (ABC) transporters are crucial in the development of resistanc
Autor:
Alicja Wolk, Edward Giovannucci, Li Li, Polly A. Newcomb, Kenneth Offit, Clemens Schafmayer, Vicente Martín, Sergi Castellví-Bel, Daniel D. Buchanan, Mingyang Song, Qianchuan He, Martha L. Slattery, Volker Arndt, Anna H. Wu, Amit Joshi, David A. Drew, D. Timothy Bishop, Annika Lindblom, Temitope O. Keku, Jochen Hampe, Ozan Dikilitas, Douglas A. Corley, John B. Harley, Hakon Hakonarson, Steven Gallinger, Noralane M. Lindor, Ian B. Stanaway, Jeffrey K. Lee, Sonja I. Berndt, Veronika Vymetalkova, Syed H.E. Zaidi, Jessica Minnier, Daniel J. Schaid, Ludmila Vodickova, John D. Potter, Heather Hampel, Christopher I. Li, Frank D. Mentch, Wei-Qi Wei, Cornelia M. Ulrich, Marc J. Gunter, Robert E. Schoen, Catherine M. Tangen, Victor Moreno, Shuji Ogino, Tabitha A. Harrison, Albert de la Chapelle, Pavel Vodicka, Andrew T. Chan, Keith R. Curtis, Elisabeth A. Rosenthal, Jenny Chang-Claude, David C. Muller, Paul D.P. Pharoah, Roger L. Milne, David Duggan, Eric B. Larson, David R. Crosslin, Andrea Gsur, Stéphane Bézieau, Graham G. Giles, Robert J. MacInnis, Bahram Namjou, Christopher H. Dampier, Gail P. Jarvik, Andrea N. Burnett-Hartman, Richard B. Hayes, Fränzel J.B. Van Duijnhoven, Wendy K. Chung, Michael Hoffmeister, Mark A. Jenkins, Mathieu Lemire, Thomas J. Hudson, Elizabeth A. Platz, Neil Murphy, Graham Casey, Michael O. Woods, Aung Ko Win, Flora Qu, Li Hsu, Emily White, Peter T. Campbell, Lori C. Sakoda, Jane C. Figueiredo, Minta Thomas, Jeroen R. Huyghe, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Corinne E. Joshu, Yu Ru Su, Ulrike Peters, Stephen B. Gruber, Demetrius Albanes, Stephen N. Thibodeau, Antoni Castells, Hermann Brenner
Publikováno v:
Am J Hum Genet
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
Accurate colorectal cancer (CRC) risk prediction models are critical for identifying individuals at low and high risk of developing CRC, as they can then be offered targeted screening and interventions to address their risks of developing disease (if
Autor:
Pavel Vodicka, Barbara Pardini, Szimonetta Turoczi, Antonio Francavilla, Sonia Tarallo, Alessio Naccarati
Publikováno v:
Mutagenesis. 35:243-260
The circulating human transcriptome, which includes both coding and non-coding RNA (ncRNA) molecules, represents a rich source of potential biomarkers for colorectal cancer (CRC) that has only recently been explored. In particular, the release of RNA
Publikováno v:
Pharmacogenomics. 20:1225-1233
DNA repair, a complex biological process, ensures genomic integrity. Alterations in DNA repair, occurring in many cancers, contribute to the accumulation of mutations in the genome, resulting in genomic instability and cancer progression. DNA repair
Publikováno v:
Molecular Aspects of Medicine. 69:73-92
Colorectal carcinogenesis is a multistep process involving the accumulation of genetic alterations over time that ultimately leads to disease progression and metastasis. Binding of transcription factors to gene promoter regions alone cannot explain t