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Publikováno v:
Experimental and Clinical Transplantation. 21:251-258
Objectives This study aimed to compare the effects of N-acetylcysteine and benfotiamine in protection of ovarian tissue from ischemia caused by slow neovascularization injury due to intraperitoneal ovarian autotransplant in rats. Materials and method
Autor:
Abdulrazaq Bidemi Nafiu, Abdulbasit Amin, Bamidele Victor Owoyele, Adedamola Bayo-Olugbami, Olalekan M. Ogundele, Charles C. Lee
Publikováno v:
Nutr Neurosci
BACKGROUND: L-DOPA, the predominant therapy for Parkinson’s disease (PD) is associated with motor deficits after prolonged use. The nigrostriatal tract, a primary target of neurodegeneration in PD, contains abundant Vitamin-D receptors, suggesting
Autor:
Celia Gellman, Jeff A. Beeler, Holly Moore, Abigail Kalmbach, Stephen Rayport, Benjamin Y. Klein, Roseanna M. Zanca, Devry Mourra, Peter A. Serrano, Susana Mingote, Rebecca Ravenelle, Nesha S. Burghardt
Publikováno v:
Biol Psychiatry
Background Increased physical activity is a common feature of anorexia nervosa (AN). Although high activity levels are associated with greater risk of developing AN, particularly when combined with dieting, most individuals who diet and exercise main
Autor:
V.P. Pishak, M.O. Ryznychuk
Publikováno v:
INTERNATIONAL JOURNAL OF ENDOCRINOLOGY (Ukraine). 13:195-202
On the long multistage pathway of biosynthesis of steroid hormones from cholesterol to cortisol, testosterone and estradiol, due to mutations in genes, there is the deficiency of steroidogenesis enzymes in the adrenal glands: cholesterol desmolase,
Autor:
Yoshinori Kakino, Maho Matsuo, Yuki Kawasaki, Chihiro Takada, Yuto Tamaoki, Ryu Yasuda, Shinji Ogura, Isamu Muraki, Toshiaki Taniguchi, Hirotsugu Fukuda, Shozo Yoshida, Takahito Miyake, Akio Suzuki, Hiroyuki Tomita, Ayumi Kuroda, Hideshi Okada, Ayane Nishio, Nagisa Miyazaki, Shigeo Takashima, Risa Inagawa, Yuichiro Kitagawa, Tomoaki Doi, Haruka Okamoto, Tetsuya Fukuta, Keiko Suzuki, Yugo Wakayama, Kodai Suzuki, Takahiro Yoshida
Publikováno v:
The American Journal of Pathology
Sepsis-induced endothelial acute respiratory distress syndrome is related to microvascular endothelial dysfunction caused by endothelial glycocalyx disruption. Recently, recombinant antithrombin (rAT) was reported to protect the endothelial glycocaly
Publikováno v:
Journal of Pharmacological Sciences, Vol 147, Iss 1, Pp 27-32 (2021)
Cigarette smoking has detrimental effects on rheumatoid arthritis (RA), characterized by muscle wasting. Linalyl acetate (LA), the main component of Lavandula angustifolia Mill (lavender) oil, has anti-inflammatory properties. We investigated the det
Autor:
Luc Zimmer, Adrian Newman-Tancredi, Sarah Chaib, Benjamin Vidal, Caroline Bouillot, Thierry Billard, Elise Levigoureux
Publikováno v:
Journal of Parkinson's disease
Journal of Parkinson's disease, Amsterdam : b : IOS Press, 2021, 11 (3), pp.1257-1269. ⟨10.3233/JPD-212580⟩
Journal of Parkinson's disease, Amsterdam : b : IOS Press, 2021, 11 (3), pp.1257-1269. ⟨10.3233/JPD-212580⟩
International audience; Background: The gold-standard treatment for Parkinson’s disease is L-DOPA, which in the long term often leads to levodopa-induced dyskinesia. Serotonergic neurons are partially responsible for this, by converting L-DOPA into
Autor:
Julia Hoeng, Sophie Scheuner, Stephanie Johne, Claudius Pak, Emmanuel Guedj, Athanasios Kondylis, Dariusz Peric, Fabio Maranzano, Romain Piault, Walter K. Schlage, Nikolai V. Ivanov, Thomas Schneider, Carine Poussin, Marco van der Toorn, Rebecca Savioz, Manuel C. Peitsch, Moran Morelli, Anne-Laure Egesipe, Shoaib Majeed, Remi Dulize, Celine Merg
Publikováno v:
Archives of Toxicology
Aging and smoking are major risk factors for cardiovascular diseases (CVD). Our in vitro study compared, in the context of aging, the effects of the aerosol of Tobacco Heating System 2.2 (THS; an electrically heated tobacco product) and 3R4F referenc
Autor:
Dennis V. Cokkinos, Michalis Katsimpoulas, Alkistis Kapelouzou, Christos Kontogiannis, Christos Papageorgiou, Irene Lidoriki, Konstantinos S. Mylonas, Alexandros Charalabopoulos, Christos Kourek, Georgios Georgiopoulos, Spyridon Dritsas
Publikováno v:
Current Issues in Molecular Biology
Volume 43
Issue 2
Pages 59-830
Current Issues in Molecular Biology, Vol 43, Iss 59, Pp 818-830 (2021)
Volume 43
Issue 2
Pages 59-830
Current Issues in Molecular Biology, Vol 43, Iss 59, Pp 818-830 (2021)
Background: A high-cholesterol diet (HCD) induces vascular atherosclerosis through vascular inflammatory and immunological processes via TLRs. The aim of this study is to investigate the mRNA expression of TLRs and other noxious biomarkers expressing
Autor:
Meliha Demiral, Edip Unal, Huseyin Demirbilek, Nezahat Doğan Karaşin, Riza Taner Baran, Mehmet Nuri Ozbek
Publikováno v:
Journal of Pediatric Endocrinology and Metabolism. 34:1463-1468
Objectives Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disorder characterised by isolated glucocorticoid deficiency. Melanocortin receptor 2 (MC2R) mediates the functions of adrenocorticotropic hormone (ACTH) in the adrenal