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Autor:
Zay Htet, Mahzuz Karim
Publikováno v:
Journal of the Royal Society of Medicine. 114(7)
Recent years have seen a paradigm shift in the management of patients with diabetes mellitus. Rather than good glycaemic control being the sole primary aim, the therapeutic focus has broadened to consider potential additional cardiovascular and renal
Autor:
Teena Mohan, Larisa V. Gubareva
Publikováno v:
Cold Spring Harbor perspectives in medicine. 12(1)
The neuraminidase (NA) of influenza A and B viruses plays a distinct role in viral replication and has a highly conserved catalytic site. Numerous sialic (neuraminic) acid analogs that competitively bind to the NA active site and potently inhibit enz
Autor:
Sonia T. Anand, Kelli K. Ryckman, William W. Terry, Laura L. Jelliffe-Pawlowski, Patrick Breheny, Rebecca J. Baer, Scott P. Oltman, Elizabeth A. Chrischilles, Mary E. Charlton, Kord M. Kober, Elizabeth E. Rogers
Publikováno v:
The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 35(25)
Leukemia and lymphoma are cancers affecting children, adolescents, and young adults and may affect reproductive outcomes and maternal metabolism. We evaluated for metabolic changes in newborns of mothers with a history of these cancers.A cross-sectio
Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
Inhaled antibiotics are commonly used to treat persistent airway infection with Pseudomonas aeruginosa that contributes to lung damage in people with cystic fibrosis. Current guidelines recommend inhaled tobramycin for individuals with cystic fibrosi
Autor:
Rustom Antia, Christiane S Eberhardt, Ali H. Ellebedy, Susanne L. Linderman, Veronika I. Zarnitsyna, Rafi Ahmed, Carl W. Davis
Publikováno v:
Cold Spring Harbor perspectives in medicine. 11(11)
Although we develop influenza immunity from an early age, it is insufficient to prevent future infection with antigenically novel strains. One proposed way to generate long-term protective immunity against a broad range of influenza virus strains is
Autor:
Rohit Sane, Prakash D. Samant
Publikováno v:
Hand (New York, N.Y.). 17(6)
Background Vitamin D deficiency is now recognized as an independent risk factor and is involved in the pathogenesis of carpal tunnel syndrome (CTS). The purpose of this study was to evaluate the effects of vitamin D3 supplementation on functional and
Autor:
Steven P. Treon, Ann S. LaCasce, Sally Tan, Anna K. Dewan, Matthew S. Davids, Nicole R. LeBoeuf, Sean Singer
Publikováno v:
Journal of the American Academy of Dermatology. 88:1271-1281
Background Ibrutinib is an oral inhibitor of Bruton’s tyrosine kinase (BTK) that is FDA-approved for several lymphoproliferative disorders and chronic GVHD. Objective To characterize cutaneous eruptions arising from ibrutinib and highlight overlap
Autor:
Julian M. Jimenez, Chenwei Duan, Craig J. Goergen, Abigail Cox, Preeti M. Sivasankar, Sarah Calve
Publikováno v:
J Voice
Summary Objectives The understanding of vocal fold hydration state, including dehydrated, euhydrated, rehydrated tissue, and how hydration affects vocal fold biomechanical properties is still evolving. Although clinical observations support the benef
Autor:
Canyang Zhang, Limian Zhou, Xiaojie Wu, Dong Zhang, Wei Miao, HaiXin Chen, Nannan Sun, Yong Gao, Yuanyuan Yu, Weihang Gao, Changhui Liu, Xiaoying Yang, Zehong Yang
Publikováno v:
Journal of Ginseng Research. 47:376-384
Background Hepatic lipid disorder impaired mitochondrial homeostasis and intracellular redox balance, triggering development of non-alcohol fatty liver disease (NAFLD), while effective therapeutic approach remains inadequate. Ginsenosides Rc has been
Autor:
Maria M. Rojas-Rojas, Jacqueline Mugnier-Quijano, David A. Suarez-Zamora, Felipe Ordoñez-Guerrero, Rocío del Pilar López-Panqueva
Publikováno v:
Revista Española de Patología. 56:113-118
Lysosomal acid lipase (LAL) deficiency is a rare, autosomal recessive disease caused by mutations in the LIPA gene, which produces cholesteryl ester and triglyceride accumulation predominantly in hepatocytes, adrenal glands, and gastrointestinal trac