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Publikováno v:
Nutr Neurosci
Diets high in saturated fat (HFD) disrupt dopamine neurotransmission, whereas fasting alters tonic and phasic dopamine release to drive motivation and food consumption. However, functional compartments in the nucleus accumbens (NAc) influencing these
Publikováno v:
BMJ Case Rep
A 57-year-old man with a history of hypertension was admitted to the emergency department with septic shock and was therefore intubated and transferred to our intensive care unit (ICU). The patient had a supracondylar knee fracture 4 months ago, and
Publikováno v:
Cold Spring Harb Perspect Med
While commendable strides have been made in reducing smoking initiation and improving smoking cessation rates, current available smoking cessation treatment options are still only mildly efficacious and show substantial interindividual variability in
Publikováno v:
Advances in Wound Care. 11:622-638
Significance: Nonhealing wounds are a significant burden for the health care system all over the world. Existing treatment options are not enough to promote healing, highlighting the urgent need for improved therapies. In addition, the current advanc
Autor:
Valina L. Dawson, Guo Li Ming, Kimberly M. Christian, Stephanie J. Temme, Weidong Li, Stephen M. Eacker, Kuei Sen Hsu, Stefan Canzar, Ki Jun Yoon, Francisca Rojas Ringeling, Ted M. Dawson, Ha Nam Nguyen, Bo Xiao, Paul F. Worley, Yu Ting Lin, Namshik Kim, Hongjun Song, Ying Zhou
Publikováno v:
Biological Psychiatry. 92:815-826
Background Gene dosage imbalance caused by copy number variations (CNVs) is a prominent contributor to brain disorders. In particular, 15q11.2 CNV duplications and deletions have been associated with autism spectrum disorder and schizophrenia, respec
Autor:
Gulce Naz Yazici, Halis Suleyman, Ercument Keskin, Mehmet Gül, Abdullah Erdogan, Mukadder Sunar
Publikováno v:
Revista Internacional de Andrología. 20:S17-S23
This study aimed to biochemically and histopathologically investigate the effect of sunitinib on oxidative testicular damage induced by ischemia/reperfusion in rats.Experimental animals were divided into three groups of six rats each: testicular tors
Autor:
Jin Jiang
Publikováno v:
Semin Cancer Biol
Cell-cell communication through evolutionarily conserved signaling pathways governs embryonic development and adult tissue homeostasis. Deregulation of these signaling pathways has been implicated in a wide range of human diseases including cancer. O
Autor:
Alice Stack, Caitriona M. Long-Smith, Yvonne M. Nolan, Denise M. O'Gorman, Stefanie Grabrucker, Erin K. Crowley
Publikováno v:
Journal of Medicinal Food. 25:924-929
Middle age is increasingly accepted as a key period during which individuals are susceptible to the effect of environmental and lifestyle factors. Emerging research indicates that dietary factors play a crucial role in brain health and cognitive func
Publikováno v:
Brazilian Journal of Otorhinolaryngology
Brazilian Journal of Otorhinolaryngology v.88 n.5 2022
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
Brazilian Journal of Otorhinolaryngology v.88 n.5 2022
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial (ABORL-CCF)
instacron:ABORL-CCF
Introduction SARS-CoV-2 is the pathogen of COVID-19. The virus is composed of the spike, membrane and envelope. On physiological smell, odoriferous substances bind to proteins secreted by sustentacular cells in order to be processed by olfactory rece
Autor:
Semra Etyemez, Akira Sawa, Usuy D. Leon Tolosa, Jay A. Gottfried, Atsushi Kamiya, Emma Janke, Hanna Jaaro-Peled, Janardhan P. Bhattarai, Minghong Ma
Publikováno v:
Seminars in Cell & Developmental Biology. 129:31-39
Olfactory dysfunction is manifested in a wide range of neurological and psychiatric diseases, and often emerges prior to the onset of more classical symptoms and signs. From a behavioral perspective, olfactory deficits typically arise in conjunction