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pro vyhledávání: '"929"'
Autor:
Xiefan Fang, Lu Zhao, Scott A. Rivkees, Christopher C. Wendler, Ryan R. Poulsen, Jingjing Wang
Publikováno v:
FEBS Open Bio, Vol 11, Iss 8, Pp 2364-2382 (2021)
FEBS Open Bio
FEBS Open Bio
We previously found that DNA methyltransferase 3a (DNMT3a) plays an important role in regulating embryonic cardiomyocyte gene expression, morphology, and function. In this study, we investigated the role of the most abundant DNMT in mammalian cells,
Autor:
Barry I. Freedman, Mary E. Comeau, Carl D. Langefeld, Swapan K Das, Donald W. Bowden, Neeraj K. Sharma
Publikováno v:
Obesity. 26:559-569
OBJECTIVE Tissue-specific gene expression is associated with individual metabolic measures. However, these measures may not reflect the true but latent underlying biological phenotype. This study reports gene expression associations with multidimensi
Autor:
Nathan E. Wineinger, Takahisa Sasho, Andrew I. Su, Kathleen M. Fisch, R. Akagi, Masahiko Saito, Martin Lotz, Oscar Alvarez-Garcia
Publikováno v:
Arthritis & Rheumatology. 68:1876-1886
Objective To analyze the methylome of normal and osteoarthritic (OA) knee articular cartilage and to determine the role of DNA methylation in the regulation of gene expression in vitro. Methods DNA was isolated from human normal (n = 11) and OA (n =