Zobrazeno 41 - 50
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Autor:
Ulrike Bingel, Johannes Wilhelmi, Johannes Kratel, Katharina Schmidt, Matthias Zunhammer, Frederik Baumann, Julian Kleine-Borgmann
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1997-2007 (2021)
Clinical and Translational Science
Clinical and Translational Science
The cold pressor test (CPT) is widely implemented and offers a simple, experimental acute pain model utilizing cold pain. Previous trials have frequently paired the CPT with opioids in order to investigate the mechanisms underlying pharmacological an
Autor:
Sofia Pedro, Michael D. George, Kaleb Michaud, Andrew Stokes, Harlan Sayles, Frederick Wolfe, Joshua F. Baker, Bryant R. England, Ted R. Mikuls
Publikováno v:
Arthritis Care Res (Hoboken)
OBJECTIVE The present study was undertaken to evaluate whether the rate of incident chronic opioid use is higher in obese patients with rheumatoid arthritis (RA). METHODS Participants with RA in the FORWARD databank were asked about their use of weak
Autor:
Başak Toğar, Selcuk Butuner, Numan Taspinar, Gokhan Arslan, Ufuk Okkay, Ahmet Hacimuftuoglu, A. M. Abd El-Aty, Erdal Agar, Ali Taghizadehghalehjoughi, Hasan Turkez, Robert L. Stephens
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 48:1662-1673
Epilepsy is a neurological disorder resulting from abnormal neuronal firing in the brain. Glutamate transporters and the glutamate-glutamine cycle play crucial roles in the development of seizures. In the present study, the correlation of epilepsy wi
Autor:
Marco A. M. Prado, Vania F. Prado, Monica S. Guzman, Helena Janickova, Mohammed A. Al-Onaizi, Ornela Kljakic, Kevin S. Chen
Publikováno v:
European Journal of Neuroscience. 54:6075-6092
Disruptions in social behaviour are prevalent in many neuropsychiatric disorders such as schizophrenia, bipolar disorder and autism spectrum disorders. However, the underlying neurochemical regulation of social behaviour is still not well understood.
Publikováno v:
Drug Alcohol Rev
Introduction Buprenorphine and methadone are highly effective first-line medications for opioid agonist treatment (OAT) but are not acceptable to all patients. We aimed to assess the uptake of slow-release oral morphine (SROM) as second-line OAT amon
Autor:
Chris G. Gill, Armin Saatchi, Scott A. Borden, Mark Lysyshyn, Gregory W. Vandergrift, Jan Palaty
Publikováno v:
Drug and Alcohol Review. 41:410-418
Introduction. Drug checking services for harm reduction and overdose prevention have been implemented in many jurisdictions as a public health intervention in response to the opioid overdose crisis. This study demonstrates the first on-site use of pa
Autor:
Adrian Lutz, Devi Stuart-Fox, Andrew F. Hugall, Iliana Medina, Katrina J. Rankin, Adam Elliott, Claire A. McLean
Publikováno v:
Ecology Letters. 24:2207-2218
Carotenoids are important pigments producing integument coloration; however, their dietary availability may be limited in some environments. Many species produce red to yellow hues using a combination of carotenoids and self-synthesised pteridine pig
Autor:
Sebastian Schneeweiss, Antonios Douros, Kristian B. Filion, Laurent Azoulay, Karine Suissa, Hui Yin, Elisabetta Patorno
Publikováno v:
Diabetes, Obesity and Metabolism. 23:2502-2512
Aims To determine whether adiposity modified the effect on the cardiovascular safety of sulfonylureas as a first-line therapy compared with metformin among patients with type 2 diabetes. Materials and methods Using the UK Clinical Practice Research D
Autor:
Anna Jöud, Jon Lampa, Sofia Ernestam, Tor Olofsson, Maria E. C. Schelin, Johan K. Wallman, Saedis Saevarsdottir, Ronald F van Vollenhoven
Publikováno v:
Arthritis Care & Research. 73:1312-1321
OBJECTIVE To compare the pain course between methotrexate (MTX)-refractory early rheumatoid arthritis (RA) patients randomized to infliximab (IFX) versus sulfasalazine (SSZ) plus hydroxychloroquine (HCQ). METHODS The randomized, controlled, open-labe
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics
What is known and objective Methotrexate‐associated lymphoproliferative disorder (MTX‐LPD) is a rare complication that develops in patients treated with methotrexate (MTX). Case summary A 76‐year‐old male patient had been taking MTX for his r