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Publikováno v:
Internal Medicine Journal. 53:68-73
Low molecular weight heparins (LMWH) are used extensively for prophylaxis and treatment of venous thromboembolism (VTE), bridging therapy for warfarin, and standard of care in cancer-associated VTE. Tinzaparin has the highest molecular weight of all
Publikováno v:
Arthritis Care & Research. 74:1451-1458
BACKGROUND The existing guidelines for lupus nephritis (LN) recommend initial prednisone doses of 0.3-1mg/kg/day. However, recent studies reported non-inferior outcomes with lower doses. The aim of this study was to compare the complete renal respons
Publikováno v:
Arthritis Care & Research. 74:1122-1132
We aimed at determining the predictors of osteonecrosis (ON) in a longitudinal lupus cohort.Data were reviewed from the initiation of the cohort in 1987 until October 2019. In total, 2,428 patients were included in the analysis based on 224,295 perso
Autor:
Benjamin Chaigne, Mickael Martin, Bénédicte Watelet, Elisabeth Diot, Claire Le Jeunne, François Maurier, Jérémie Dion, Luc Mouthon, Cloé Giret, Jean François Viallard, Sabine Berthier, Pascal Priollet, Marie-Elise Truchetet, Alain Lescoat, Olivier Cerles, Dorothée Fagedet, Cyril Cosse, Loic Raffray, Brigitte Granel, Christelle Nguyen, J. Bertolino, Ségolène Toquet, Solen Kernéis, David Luque Paz, Wendy Jourde, Christian Agard, Grégory Pugnet
Publikováno v:
Arthritis Care & Research. 74:809-817
Systemic sclerosis (SSc) is an autoimmune connective tissue disorder characterized by skin fibrosis, vasculopathy, and dysimmunity. Data regarding osteitis in SSc are scarce.We performed a nationwide multicenter, retrospective, case-control study inc
Autor:
Kateřina Sheardová, Gustavo Sevlever, Victoria David-Dirgo, Marian Hajduch, Patrick Pirrotte, Clara Limbäck-Stokin, Ritin Sharma, Durga Jha, Robert A. Rissman, Lucia Pertierra, Maria Carna, Richard A. G. Smith, Petr Kaňovsky, Nadine Bakkar, Valentina Lacovich, Hana Markova, Mojmir Vinkler, Giancarlo Forte, Jiri Damborsky, Jan Fric, Silvie Belaskova, Krystine Garcia-Mansfield, Hernan Chaves, Eric B. Dammer, Marketa Nezvedova, Ruben Houbrechts, Gorazd B. Stokin, Nicholas T. Seyfried, Robert Bowser, Martin Vyhnalek, Zuzana Nedelska, Stanislav Katina, Kateřina Texlova, Jan Laczó, Isaac G. Onyango, Thijs Vande Vyvere, Dusan Holub, Zdenek Spacil, Jakub Hort
Publikováno v:
Alzheimer´s & Dementia
Alzheimer’s disease is a neurodegenerative disorder characterized clinically by cognitive decline and pathologically by amyloid deposition and neurofibrillary changes. These neuropathological hallmarks are accompanied by reactive events including m
Autor:
Juergen Rech, Andreas Ramming, David Simon, Cong Duy Bui, Holger Bang, Axel J. Hueber, Georg Schett, Arnd Kleyer
Publikováno v:
Arthritis and Rheumatology
To assess if microstructural bone lesions in individuals at risk of developing rheumatoid arthritis (RA) are related to the spectrum of anti-modified protein antibodies (AMPAs) and affect the risk of developing RA.Cortical microchannels as well as co
Autor:
Edith Borcoman, Christophe Le Tourneau, Grégoire Vuagniaux, Sébastien Vergez, Jérôme Sarini, Neus Baste, Philippe Rochaix, Franck Brichory, Annick Menetrey, Stéphane Temam, Claudio Zanna, Elisabeth Rouits, Carlos Gomez-Roca, Jean-Pierre Delord, Daniela Purcea, Caroline Hoffmann, Caroline Even, Bruno Gavillet
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 1, Pp 55-62 (2022)
Clinical and Translational Science
Clinical and Translational Science
Inhibitor of apoptosis proteins (IAPs) regulate apoptosis and modulate NF‐κB signaling thereby driving expression of genes involved in immune/inflammatory responses. The orally available IAP antagonist Debio 1143 has potential to enhance tumor res
Autor:
Peter Gibbs, Margaret Lee, Lara Lipton, Belinda Lee, Sumitra Ananda, Rachel Wong, Prasad Cooray, Jeremy Shapiro, Azim Jalali, Amy Body, Sue-Anne McLachlan
Publikováno v:
Internal Medicine Journal. 52:49-56
BACKGROUND: Metastatic pancreatic ductal adenocarcinoma (mPDAC) is highly lethal. Combination chemotherapy regimens improve overall survival (OS). Historically, only one third of mPDAC patients in Victoria received chemotherapy (1) . AIM: To describe
Autor:
Alicia Probst, Emilie De Carli, Isabelle Aerts, Pascal Chastagner, Natacha Entz-Werle, Caroline Solas, Anne-Isabelle Bertozzi-Salamon, Nicolas André, Anne Pagnier, Emmanuelle Tresch-Bruneel, Pierre Leblond, Jacques Grill, Didier Frappaz, Mourad Hamimed, Florence Gattacceca
Publikováno v:
British Journal of Clinical Pharmacology
British Journal of Clinical Pharmacology, 2021, ⟨10.1111/bcp.15131⟩
British Journal of Clinical Pharmacology, Wiley, 2021, ⟨10.1111/bcp.15131⟩
British Journal of Clinical Pharmacology, 2021, ⟨10.1111/bcp.15131⟩
British Journal of Clinical Pharmacology, Wiley, 2021, ⟨10.1111/bcp.15131⟩
AIM There is a crucial need for pharmacokinetic (PK) data of oral vinorelbine (VNR) in pediatric population. The aim of this work was to assess the PK profile of orally administered VNR in children with recurrent/progressive primary low-grade glioma
Autor:
Antti Mäkitie, Karin Blomgren, Markus Lilja, Ida Kotisalmi, Maija Hytönen, Sara Sainio, Marie Lundberg
Publikováno v:
Clinical Otolaryngology. 47:174-180
Publisher Copyright: © 2021 John Wiley & Sons Ltd Objectives Postoperative infection is the most common complication after septoplasty. Pre- or postoperative prophylactic antibiotics are commonly used, although no official guidelines exist. Design W