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Autor:
Lu Lu, Hou Guojun, Yong Zhou, Lu Sun, Yu Jiajian, Fengling Huang, Yadong Zhou, Zhixian Guo, Yize Zhang, Zihui Dong, Yu Ting, Wang Bibo
Publikováno v:
Cellular Oncology (Dordrecht)
Purpose Lenvatinib is a long-awaited alternative to Sorafenib for first-line targeted therapy of patients with advanced hepatocellular carcinoma (HCC). However, resistance to Lenvatinib results in tumor progression and has become a major obstacle to
Publikováno v:
Mycopathologia
Tinea capitis is a type of dermatophyte infection primarily affecting children. We report a case of an elderly woman with well-controlled diabetes mellitus presenting with a six-month history of erythema with yellow crusts on her scalp and extensive
Publikováno v:
Biotechnology Letters
Objective Evaluation of morphology and secondary metabolites production in Aspergillus terreus ATCC 20542 cultures over a wide range of lactose and yeast extract concentrations from 0.2 up to an extremely high level of 200 g l−l. Results The morpho
Autor:
Nina N. Seel, Verena Liu, Mario H. Müller, Ioannis Pozios, Martin E. Kreis, Christiane J. Bruns, Lisa Hartmann, Nina A. Hering, Hendrik Seeliger, Peter Camaj, Lucas D. Lee
Publikováno v:
Cellular Oncology (Dordrecht)
Purpose Currently, the exact role of estrogen receptor (ER) signaling in pancreatic cancer is unknown. Recently, we showed that expression of phosphorylated ERβ correlates with a poor prognosis in patients with pancreatic ductal adenocarcinoma (PDAC
Publikováno v:
Biotechnology Letters
Objective Regio- and stereoselective hydroxylation of lithocholic acid (LCA) using CYP107D1 (OleP), a cytochrome P450 monooxygenase from the oleandomycin synthesis pathway of Streptomyces antibioticus. Results Co-expression of CYP107D1 from S. antibi
Autor:
Nathieli B. Bottari, Mateus Fracasso, Anielen D. Silva, Maria Rosa Chitolina Schetinger, Silvia Gonzalez Monteiro, Karine Paula Reichert, Aleksandro Schafer da Silva
Publikováno v:
Purinergic Signal
Chagas disease (CD) is caused by the parasite Trypanosoma cruzi. CD affects people worldwide, primarily in tropical areas. The central nervous system (CNS) is an essential site for T. cruzi persistence during infection. The protozoan may pass through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71ea08140bd427f31eecaf0f82254825
https://europepmc.org/articles/PMC8410899/
https://europepmc.org/articles/PMC8410899/
Publikováno v:
Purinergic Signal
Adenosine triphosphate (ATP) and its metabolites adenosine diphosphate, adenosine monophosphate, and adenosine in purinergic signaling pathway play important roles in many diseases. Activation of P2 receptors (P2R) channels and subsequent membrane de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8e7567dfb641597ce56353cbe8def7
https://europepmc.org/articles/PMC8155138/
https://europepmc.org/articles/PMC8155138/
Publikováno v:
Molecular Biology Reports
Mol Biol Rep
Mol Biol Rep
Pancreatic β cell damage is one of the crucial factors responsible for the development of type 2 diabetes mellitus (T2DM). Previous studies have suggested that puerarin (PR) could regulate the activities of the mitochondrial respiratory chain comple
Autor:
Yan Li, Jian Suo, Harshul Pandit, Xuanyi Li, Russell W. Farmer, Xuan Sun, Robert C. G. Martin, Kevin Jacob, Qianqian Zheng
Publikováno v:
Cellular Oncology (Dordrecht)
Background With a less than 5% overall survival rate, esophageal adenocarcinoma (EAC) is one of the leading causes of death in the United States. Epithelial cell adhesion molecule (EpCAM) is a cancer stem cell (CSC) marker that is expressed in variou
Publikováno v:
Cell Stress Chaperones
Diabetic retinopathy (DR) is a serious microvascular complication of diabetes. Gambogic acid has been reported to have anti-inflammatory effect. However, the effect of GA on inflammatory response of ARPE-19 cells remains unclear. In our study, ARPE-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8e1f984b8c4ebfdca5a21f46b2f1c4
https://europepmc.org/articles/PMC7925800/
https://europepmc.org/articles/PMC7925800/