Zobrazeno 1 - 10
of 25
pro vyhledávání: ''
Autor:
Drew W. Rasco, Amita Patnaik, Kristen McEachern, Sharon Lu, Wei Guo, Lisa Blaydorn, Murali Beeram, Ellie Im, Amy Mirabella, Jasgit C. Sachdev, Hadi Danaee, Glen J. Weiss
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose New immuno-oncology therapies targeting programmed cell death receptor 1 (PD-1) have improved patient outcomes in a broad range of cancers. The objective of this analysis was to evaluate the PK, pharmacodynamics (PDy), and safety of dostarlim
Autor:
Yusuke Kaida, Naoki Inui, Kazuki Furuhashi, Yusuke Inoue, Tomohiro Uto, Katsuhiro Yoshimura, Kazutaka Mori, Noriyuki Enomoto, Mitsuru Niwa, Hiroyuki Matsuda, Shun Matsuura, Yuzo Suzuki, Yutaro Nakamura, Masato Fujii, Masato Karayama, Hironao Hozumi, Mikio Toyoshima, Yasuhiro Ito, Takafumi Suda, Dai Hashimoto, Tomoyuki Fujisawa, Hideki Kusagaya, Takashi Matsui, Nao Inami, Kazuhiro Asada
Publikováno v:
Cancer Immunology, Immunotherapy
Background Lipids have immunomodulatory functions and the potential to affect cancer immunity. Methods The associations of pretreatment serum cholesterol and long-chain fatty acids with the objective response rate (ORR), progression-free survival (PF
Autor:
Antonia Strippoli, Alessandra Cocomazzi, Carmelo Pozzo, Maria Alessandra Calegari, Michele Basso, Riccardo Ricci, Carlo Barone, Mariantonietta Di Salvatore, I. Zurlo, Mattia Schino, Giampaolo Tortora, Maurizio Martini, Alessandra Cassano, Luigi Maria Larocca, Emilio Bria
Publikováno v:
Cancer Immunology, Immunotherapy
The combination of perioperative chemotherapy plus complete surgical resection is currently accounted as the first-choice strategy in patients with locally advanced Gastric Cancer (LAGC). Nevertheless, the partial response rate makes it necessary to
Autor:
Jürgen C. Becker, Stephan Grabbe, Ulrike Leiter, Henner Stege, Claudia Pföhler, Peter Mohr, Jessica C. Hassel, Carmen Loquai, S. Schultheis, Felix Kiecker, S. Ugurel, Maximilian Haist, Patrick Terheyden, Markus Meissner, Maria Isabel Fleischer, J. Kleeman, A. Thiem
Publikováno v:
Cancer Immunology, Immunotherapy
Background Immune checkpoint inhibitors (ICI) have led to a prolongation of progression-free and overall survival in patients with metastatic Merkel cell carcinoma (MCC). However, immune-mediated adverse events due to ICI therapy are common and often
Autor:
Oliver Bähr, Katharina Filipski, Michael W. Ronellenfitsch, Iris Divé, Joachim P. Steinbach, Marie Therese Forster, Pia S. Zeiner, Patrick N. Harter, Emmanouil Fokas, Marlies Wagner, Eike Steidl
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Classification and treatment of WHO grade II/III gliomas have dramatically changed. Implementing molecular markers into the WHO classification raised discussions about the significance of grading and clinical trials showed overall survival (O
Autor:
Cornelia Becker, Wolfram Pönisch, Maik Schwarz, Markus Scholz, Madlen Jentzsch, Uwe Platzbecker, Andreas Schwarzer, Bruno Holzvogt, Georg-Nikolaus Franke, Uta Schönfelder-Fricke, Juliane Grimm, Leanthe Braunert, Yvonne Remane, Marc Andrea, Thomas Zehrfeld, Sebastian Schwind, Thomas Edelmann, Franz Albert Hoffmann, Tanja Holzhey, Song-Yau Wang, Doreen Hammerschmidt, Markus Bill, Madlen Holzvogt
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Introduction Light chain involvement is observed in almost every patient (pt) with newly diagnosed multiple myeloma (MM). Owing to a relatively short half-life, rapid reduction in the involved free light chain (iFLC) is of potential prognostic value.
Autor:
Darshana Patil, Sewanti Limaye, Amit Bhatt, Prashant Kumar, Tim Crook, Sanket Patil, Raymond L. Page, Anantbhushan Ranade, Dadasaheb Akolkar, Andrew Gaya
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose Selection of cytotoxic chemotherapy agents (CCA) based on pre-treatment evaluation of drug sensitivities is a desirable but unmet goal for personalized anticancer treatment strategies. Prior attempts to correlate in vitro Chemo-Response Profi
Autor:
Alex Federico, Francesco Legge, Francesco Fanfani, Giovanni Scambia, Francesca Ciccarone, Martina Arcieri, Francesco Cosentino, Enrico Vizza, Luigi Carlo Turco, Camilla Certelli, Andrea Rosati, Gabriella Ferrandina, Giacomo Corrado
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Objective The aim of this retrospective study was to compare surgical and survival outcome in only patients with early-stage UCSs managed by laparotomic surgery (LPT) versus minimally invasive surgery (MIS). Methods Data were retrospectively collecte
Autor:
Utz Settmacher, Herman Kissler, Annelore Altendorf-Hofmann, A. Bauschke, Michael Ardelt, Hans-Michael Tautenhahn
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Background It has been shown that local ablative procedures enable downsizing, reduce drop-out from the waiting list and improve prognosis after liver transplantation. It is still unclear whether a response to the local ablative therapy is due to a f
Autor:
Bei Wang, Rong Deng, Stefanie Hennig, Tanja Badovinac Crnjevic, Monika Kaewphluk, Matts Kågedal, Angelica L. Quartino, Sandhya Girish, Chunze Li, Whitney P. Kirschbrown
Publikováno v:
Cancer Chemother Pharmacol
To characterize pertuzumab pharmacokinetics (PK) in FeDeriCa (NCT03493854: fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection [PH FDC SC] versus intravenous pertuzumab plus trastuzumab); derive individual pertuzumab expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538e107dbe76eb417f4a52751c79fdf6
https://europepmc.org/articles/PMC9172816/
https://europepmc.org/articles/PMC9172816/