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Autor:
Kai Qin, Danni Jian, Yaqiang Xue, Yi Cheng, Peng Zhang, Yaxun Wei, Jing Zhang, Huihua Xiong, Yi Zhang, Xianglin Yuan
Publikováno v:
Oncology Reports
DEAD‑box helicase 41 (DDX41) is an RNA helicase and accumulating evidence has suggested that DDX41 is involved in pre‑mRNA splicing during tumor development. However, the role of DDX41 in tumorigenesis remains unclear. In order to determine the f
Publikováno v:
Oncology Reports
Rho family GTPase 3 (RND3) is involved in multiple physiological activities involving the Rho kinase‑dependent signaling pathway. The present study revealed a novel role of RND3 in the regulation of apoptosis in the brain. Using immunofluorescence
Autor:
Kyu Hyung Han, Su Bin Cho, Jong Kook Park, Won Sik Eum, Yeon Joo Choi, Keun Wook Lee, Duk Soo Kim, Dae Won Kim, Hyun Jung Kwon, Min Jea Shin, Hyeon Ji Yeo, Soo Young Choi, Sung-Woo Cho, Jinseu Park, Eun Ji Yeo
Publikováno v:
International Journal of Molecular Medicine. 47:751-760
Aldose reductase (AR) is known to detoxify aldehydes and prevent oxidative stress. Although AR exerts antioxidant effects, the role of AR in Parkinson's disease (PD) remains unclear. The objective of the present study was to investigate the protectiv
Autor:
Xuanxiang Luo, Zhe Qu, Menghan Cao, Feng Yuan, Tianqun Huo, Hu Feng, Li Jing, Bin Pan, Kaijin Guo
Publikováno v:
International Journal of Molecular Medicine
Ligamentum flavum hypertrophy (LFH) is an important cause of spinal canal stenosis and posterior longitudinal ligament ossification. Although a number of studies have focused on the mechanisms responsible for LFH, the cellular mechanisms remain poorl
Publikováno v:
International Journal of Molecular Medicine
The mitochondria have been proven to be involved in processes of aging; however, the mechansims through which mitoepigenetics affect the cytological behaviors of cardiomyocytes during the aging process are not yet fully understood. In the present stu
Autor:
Kuida Chen, Tianqi Xu, Dangdang Li, Jialiang Li, Ke Shi, Jingru Hu, Guangyue Li, Guangchao Sui, Tianxin Li, Kazushi Inoue
Publikováno v:
International Journal of Oncology
The cyclin D binding myb‑like transcription factor 1 (DMTF1), a haplo‑insufficient tumor suppressor gene, has 3 alternatively spliced mRNA isoforms encoding DMTF1α, β and γ proteins. Previous studies have indicated a tumor suppressive role of
Publikováno v:
International Journal of Molecular Medicine
The erythroid differentiation regulator 1 (Erdr1) protein has been studied for its role in various inflammatory skin diseases, including skin cancer, actinic keratosis and psoriasis. However, the therapeutic effects of Erdr1 on wound repair and its u
Autor:
Lirong Xu, Xiaoli Xu, Zhixiao Lin, Nan Pang, Xueyong Li, Rong Huang, Xiaolin Wang, Xingxing Li, Jinqing Li
Publikováno v:
Molecular Medicine Reports
Wound healing is a complex physiological process in which fibrocytes serve a vital role. However, the mechanism underlying the recruitment of fibrocytes during wound healing remains largely unknown. The present study aimed to investigate whether endo
Publikováno v:
Molecular Medicine Reports
Oxyresveratrol (ORES) is a natural phenolic compound with multiple biological functions including antioxidation, anti‑inflammation and neuroprotection; however, the inhibitory effect of ORES on osteosarcoma remains largely unknown. The present stud
Autor:
Songping Yu, Xu Yang, Cai Xinyong, Lang Hong, Hong Zeng, Liang Shao, Bin Li, Ping Zhang, Shu Wang
Publikováno v:
Molecular Medicine Reports
FGD5 antisense RNA 1 (FGD5‑AS1) is a long non‑coding RNA in acute myocardial infarction (AMI), which is primarily caused by myocardial ischemia‑hypoxia. Retinoid acid receptor‑related orphan receptor α (RORA) is a key protector in maintainin