Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Smith, David A."'
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 14, Iss 2, p e1006012 (2018)
PLoS Computational Biology, Vol 14, Iss 2, p e1006012 (2018)
Here we formulate a mechanistic mathematical model to describe the growth dynamics of P. aeruginosa in the presence of the β-lactam antibiotic meropenem. The model is mechanistic in the sense that carrying capacity is taken into account through the
Autor:
Greggio, Elisa, Leong, Su Ling, Hinds, Mark G., Connor, Andrea R., Smith, David, Illes-Toth, Eva, Pham, Chi L. L., Barnham, Kevin J., Cappai, Roberto
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 2, p e0116497 (2015)
PLoS ONE, Vol 10, Iss 2, p e0116497 (2015)
α-synuclein (α-syn) is a major component of the intracellular inclusions called Lewy bodies, which are a key pathological feature in the brains of Parkinson's disease patients. The neurotransmitter dopamine (DA) inhibits the fibrillisation of α-sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ea5858d4eebad0ebefabd701a23caf
https://shura.shu.ac.uk/9508/1/Smith_N_terminal_residues_43_to_60.pdf
https://shura.shu.ac.uk/9508/1/Smith_N_terminal_residues_43_to_60.pdf
Autor:
Leonenko, Zoya, Smith, Rachel A. S., Nabok, Aleksey, Blakeman, Ben J. F., Xue, Wei-Feng, Abell, Benjamin, Smith, David P.
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 7, p e0132309 (2015)
PLoS ONE, Vol 10, Iss 7, p e0132309 (2015)
There is an ongoing debate regarding the culprits of cytotoxicity associated with amyloid disorders. Although small pre-fibrillar amyloid oligomers have been implicated as the primary toxic species, the fibrillar amyloid material itself can also indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1dbda1079fbdd249a4d5a243304c677
Autor:
Christopher A. Gilligan, João A. N. Filipe, Christopher A. Lee, Richard Cobb, Yana Valachovic, Alex R. Cook, Ross K. Meentemeyer, David M. Rizzo
Publikováno v:
PLoS Computational Biology
PLoS computational biology, vol 8, iss 1
PLoS Computational Biology, Vol 8, Iss 1, p e1002328 (2012)
PLoS computational biology, vol 8, iss 1
PLoS Computational Biology, Vol 8, Iss 1, p e1002328 (2012)
Exotic pathogens and pests threaten ecosystem service, biodiversity, and crop security globally. If an invasive agent can disperse asymptomatically over long distances, multiple spatial and temporal scales interplay, making identification of effectiv