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Autor:
Henny J. M. Beckers, Hellen C S Römkens, Tos T. J. M. Berendschot, Carroll A.B. Webers, Jan S. A. G. Schouten
Publikováno v:
Eye, 36, 167-174. Nature Publishing Group
Eye (Lond)
Eye, 36(1), 167-174. Nature Publishing Group
Eye (Lond)
Eye, 36(1), 167-174. Nature Publishing Group
PURPOSE: To assess the usefulness of water drinking test and dark room provocative testing (WDT + DRPT) in current clinical practice by evaluating input parameters from Swept-source Optical Coherence Tomography (SS-OCT) images, and to determine if cl
Autor:
Alissa Visram, Francis K. Buadi, Wilson I. Gonsalves, S. Vincent Rajkumar, Angela Dispenzieri, Martha Q. Lacy, Rahma Warsame, Morie A. Gertz, Eli Muchtar, Shaji Kumar, Robert A. Kyle, Nelson Leung, David Dingli, Linda B. Baughn, Suzanne R. Hayman, Prashant Kapoor, Taxiarchis Kourelis
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 11, Pp 1-8 (2021)
Blood Cancer Journal
Blood Cancer Journal
The Mayo-2018 smoldering multiple myeloma (SMM) risk score is used routinely in the clinical setting but has only been validated at diagnosis. In SMM patients, the progression risk decreases over time. However, the utility of applying risk stratifica
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
STEAP3 (Six-transmembrane epithelial antigen of the prostate 3, TSAP6, dudulin-2) has been reported to be involved in tumor progression in human malignancies. Nevertheless, how it participates in the progression of human cancers, especially HCC, is s
Autor:
Martin Binks, John A. Dawson, Allison Childress, Chathurika S. Dhanasekara, Nikhil V. Dhurandhar
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-8 (2021)
Nutrition & Diabetes
Nutrition & Diabetes
Background/Objectives High egg consumption is associated with poor glycemic control. Considering the widespread consumption of eggs, it is crucial to determine causality in this association. We tested if egg consumption acutely alters glucose disposa
Autor:
Mark-David Levin, Paula F. Ypma, Sonja Zweegman, Monique C. Minnema, Pieter Sonneveld, Esther G. M. de Waal, Eduardus F. M. Posthuma, Mirian Brink, Kaz Groen, Niels W.C.J. van de Donk, Ellen van der Spek, Avinash G Dinmohamed, Annemiek Broijl
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 11, Pp 1-7 (2021)
Blood Cancer Journal, 11(11):178. Nature Publishing Group
Blood Cancer Journal
Brink, M, Groen, K, Sonneveld, P, Minnema, M C, Broijl, A, Dinmohamed, A G, van der Spek, E, Levin, M D, Ypma, P F, de Waal, E, Posthuma, E F M W, Zweegman, S & van de Donk, N W C J 2021, ' Decrease in early mortality for newly diagnosed multiple myeloma patients in the Netherlands : a population-based study ', Blood cancer journal, vol. 11, no. 11, 178 . https://doi.org/10.1038/s41408-021-00571-8
Blood cancer journal, 11(11):178. Nature Publishing Group
Blood Cancer Journal, 11(11):178. Nature Publishing Group
Blood Cancer Journal
Brink, M, Groen, K, Sonneveld, P, Minnema, M C, Broijl, A, Dinmohamed, A G, van der Spek, E, Levin, M D, Ypma, P F, de Waal, E, Posthuma, E F M W, Zweegman, S & van de Donk, N W C J 2021, ' Decrease in early mortality for newly diagnosed multiple myeloma patients in the Netherlands : a population-based study ', Blood cancer journal, vol. 11, no. 11, 178 . https://doi.org/10.1038/s41408-021-00571-8
Blood cancer journal, 11(11):178. Nature Publishing Group
Identification of risk factors for early mortality (EM) in multiple myeloma (MM) patients may contribute to different therapeutic approaches in patients at risk for EM. This population-based study aimed to assess trends in EM and risk factors for EM
Autor:
Zhigang Tian, Xiaokun Shen, Rui Sun, Chuang Guo, Binqing Fu, Haiming Wei, Jiabin Li, Dongyao Wang, Ying Ye, Junfei Zhang, Yanyan Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Patients with chronic hepatitis B (CHB) undergoing interferon (IFN)-α-based therapies often exhibit a poor HBeAg serological response. Thus, there is an unmet need for new therapies aimed at CHB. This study comprised two clinical trials, including 1
Autor:
Walter J.F.M. van der Velden, Anton F.J. de Haan, Nicole M. A. Blijlevens, Suzanne van Dorp, Jürgen Kuball, Moniek de Witte, Goda Choi, Arnold van der Meer, Gerwin Huls
Publikováno v:
Bone Marrow Transplantation, 56, 2651-2655
Bone Marrow Transplantation, 56, 11, pp. 2651-2655
Bone Marrow Transplantation
Bone marrow transplantation, 56(11), 2651-2655. Nature Publishing Group
Bone Marrow Transplantation, 56, 11, pp. 2651-2655
Bone Marrow Transplantation
Bone marrow transplantation, 56(11), 2651-2655. Nature Publishing Group
Contains fulltext : 241342.pdf (Publisher’s version ) (Closed access) Nonmyeloablative regimens are used for allogeneic hematopoietic cell transplantation (HCT) of older or medically unfit patients, but successful outcome is still hindered by graft
Autor:
Gordon D. Waiter, Claire Green, Mathew A. Harris, J. Douglas Steele, Anca-Larisa Sandu, Joanna M. Wardlaw, David J. Porteous, Heather C. Whalley, Liana Romaniuk, Emma L. Hawkins, Rebecca M. Reynolds, Xueyi Shen, Miruna C. Barbu, Aleks Stolicyn, Jonathan R. Seckl, Andrew M. McIntosh, Stephen M. Lawrie, Jonathan Cavanagh, Archie Campbell
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Green, C, Stolicyn, A, Harris, M A, Shen, X, Romaniuk, L, Barbu, M C, Hawkins, E L, Wardlaw, J M, Steele, J D, Waiter, G D, Sandu, A, Campbell, A, Porteous, D J, Seckl, J R, Lawrie, S M, Reynolds, R M, Cavanagh, J, Mcintosh, A M & Whalley, H C 2021, ' Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland ', Translational Psychiatry, vol. 11, no. 1 . https://doi.org/10.1038/s41398-021-01644-9
Translational Psychiatry
Green, C, Stolicyn, A, Harris, M A, Shen, X, Romaniuk, L, Barbu, M C, Hawkins, E L, Wardlaw, J M, Steele, J D, Waiter, G D, Sandu, A, Campbell, A, Porteous, D J, Seckl, J R, Lawrie, S M, Reynolds, R M, Cavanagh, J, Mcintosh, A M & Whalley, H C 2021, ' Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland ', Translational Psychiatry, vol. 11, no. 1 . https://doi.org/10.1038/s41398-021-01644-9
Hypothalamic–pituitary–adrenal (HPA) axis dysregulation has been commonly reported in major depressive disorder (MDD), but with considerable heterogeneity of results; potentially due to the predominant use of acute measures of an inherently varia
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-7 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
This study (ORIENT-4) aimed to assess the efficacy and safety of sintilimab, a humanized anti-PD-1 antibody, in patients with relapsed/refractory extranodal NK/T cell lymphoma (r/r ENKTL). ORIENT-4 is a multicenter, single-arm, phase 2 clinical trial
Autor:
Xiangkai Zhang, Shuli Liu, Jiong Deng, Yong Han, Liu Liu, Yang Wang, Shengming Xu, Zhiyuan Zhang, Weimin Ye
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive tumor with poor clinical outcomes due to recurrence, metastasis, and treatment resistance. Cancer stem cells (CSCs), a small population among tumor cells, are proposed to be respons