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Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-6 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
In response to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, over 200 vaccine candidates against coronavirus disease 2019 (COVID-2019) are under development and currently moving forward at an unparalleled speed. The avail
Autor:
John Patrick Aggleton, Emma Jane Kidd, Jilu P. Mole, John Evans, Claudia Metzler-Baddeley, Fabrizio Fasano, Rebecca Sims
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-25 (2020)
Scientific Reports
Scientific Reports
APOE-ε4 is a main genetic risk factor for developing late onset Alzheimer’s disease (LOAD) and is thought to interact adversely with other risk factors on the brain. However, evidence regarding the impact of APOE-ε4 on grey matter structure in as
Autor:
Dalia A. Gaber, Karim Montasser, Wael M. Elayat, Mohamed I. El-Moazen, Rita Wassef, Sherif A. Swar, Hebat Allah A. Amin
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Urinary bladder cancer is a common malignancy in Egypt, thus reliable methodologies are required for screening and early detection. In this study, we analyzed the gene expression of a Schistosoma hematobium specific microRNA “Sha-miR-71a” and mit
Autor:
C. M. Broughton, Arturas Grauslys, Rebecca Jennings, S. Siner, Stéphane Paulus, Paul Baines, Marie M. Phelan, Enitan D. Carrol
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
SCIENTIFIC REPORTS
Scientific Reports
SCIENTIFIC REPORTS
Sepsis, defined as life-threatening organ dysfunction caused by infection is difficult to distinguish clinically from infection or post-operative inflammation. We hypothesized that in a heterogeneous group of critically ill children, there would be d
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Measuring the Parathyroid hormone (PTH) levels assists in the investigation and management of patients with parathyroid disorders. Rapid PTH monitoring is a valid tool for accurate assessment intraoperatively. Rapid Electro-Analytical Device (READ) i
Autor:
Ruey Hsing Chou, Shao Sung Huang, Po Hsun Huang, Chun Chin Chang, Shing Jong Lin, Ya Wen Lu, Shen-Chih Wang, Yi Lin Tsai, Chin Sung Kuo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Galectin-1, a β-galactoside-binding lectin mediating inflammation and neovascularization, is reported to attenuate ventricular remodeling after myocardial infarction. But its role in stable coronary artery disease (CAD) has not been fully elucidated
Autor:
Soon Jun Hong, Cheol Woong Yu, Jae Hyoung Park, Jae Young Cho, Duck Hyun Jang, Jong-Ho Kim, Hyung Joon Joo, Sang A. Cho, Do Sun Lim, Hyungdon Kook
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1), neutrophil gelatinase-associated lipocalin (NGAL), and matrix metalloproteinase-9 (MMP-9) are inflammatory biomarkers involved in plaque destabilization resulting in acute coro
Autor:
Anastasia Xourafa, Rosario Rapisarda, Luca Zanoli, Agostino Gaudio, Pietro Castellino, Salvatore Santo Signorelli, Antonino Catalano
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Osteoporosis and atherosclerosis are significant public health problems that often coexist, especially in the elderly. Although some studies have reported an age-dependent relationship, others have suggested a causal relationship between osteoporosis
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
This study aimed to determine the risk factors related to regression and progression of metabolic syndrome, in a 4-year cohort study. A total of 540 individuals (≥ 18 years old) participated in both phase of the study. Participants were categorized
Autor:
Yuqiao Cen, Ahyeon Koh, Lina Begdache, Nicholas Linehan, Peter Pearlmutter, Cheyenne Samson, Daehan Won, Gia Derose
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Cortisol is a biomarker for stress monitoring; however, the biomedical and clinical relevance is still controversial due to the complexity of cortisol secretion mechanisms and their circadian cycles as well as environmental factors that affect physio