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Autor:
Tong Shen, Youlutuziayi Rixiati, Ling-Dong Cai, Jian-Ming Li, Jing-Lin Liu, Chu-Yi Wang, Yuan-Yuan Zhao, Shi Li
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-18 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
The mechanisms and key factors involved in tumor environments for lung metastasis of CRC are still unclear. Here, using clinical samples from lung metastases of CRC patients, we found that intestinal immune network for IgA production was significantl
Autor:
Yan Gao, Jun Cai, Yi Xia, Qingqing Cai, Shuyun Ma, Yuchen Zhang, Lirong Li, Xiaopeng Tian, Hang Yang, Panpan Liu, Yajun Li, Xuanye Zhang, Hui Zhou, Huiqiang Huang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-9 (2020)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Advanced natural killer/T cell lymphoma (NKTL) has demonstrated poor prognosis with currently available therapies. Here, we report the efficacy of anti-programmed death 1 (PD-1) antibody with the P-GEMOX (pegaspargase, gemcitabine, and oxaliplatin) r
Autor:
Katsumi Shozugawa, Thomas E. Johnson, Motoyuki Matsuo, Naoto Takahata, Norbert Kávási, Mayumi Hori, Sarata Kumar Sahoo, Yuji Sano
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
There has been tritium groundwater leakage to the land side of Fukushima Dai-ichi nuclear power plants since 2013. Groundwater was continuously collected from the end of 2013 to 2019, with an average tritium concentration of approximately 20 Bq/L. Ba
Autor:
Michael Nilsson, Lin Kooi Ong, Murielle G. Kluge, Wei Zhen Chow, Frederick R. Walker, Prajwal Gyawali
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
For many chronic stroke survivors, persisting cognitive dysfunction leads to significantly reduced quality of life. Translation of promising therapeutic strategies aimed at improving cognitive function is hampered by existing, disparate cognitive ass
Autor:
John Patrick Aggleton, Emma Jane Kidd, Jilu P. Mole, John Evans, Claudia Metzler-Baddeley, Fabrizio Fasano, Rebecca Sims
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-25 (2020)
Scientific Reports
Scientific Reports
APOE-ε4 is a main genetic risk factor for developing late onset Alzheimer’s disease (LOAD) and is thought to interact adversely with other risk factors on the brain. However, evidence regarding the impact of APOE-ε4 on grey matter structure in as
Autor:
Akira Fukuya, Yasuo Takahashi, Masahiro Hirakawa, Yasushi Sato, Hiroshi Miyamoto, Kyoko Hamaguchi, Tetsuji Takayama, Naoki Muguruma, Tamotsu Sagawa, Koshi Fujikawa, Koichi Okamoto
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The primary tumour location is an important prognostic factor for previously untreated metastatic colorectal cancer (mCRC). However, the predictive efficacies of primary tumour location, early tumour shrinkage (ETS), and depth of response (DpR) on mC
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Scientific Reports
Scientific Reports
A three dimensional (3D) numerical solution of unsteady, Ag-MgO hybrid nanoliquid flow with heat and mass transmission caused by upward/downward moving of wavy spinning disk has been scrutinized. The magnetic field has been also considered. The hybri
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
In this work, the tip convolution effect in atomic force microscopy is revisited to illustrate the capabilities of cubic objects for determination of the tip shape and size. Using molecular-based cubic nanoparticles as a reference, a two-step tip rec
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Cannabidiol (CBD) has anti-tumorigenic activity. However, the anti-cancer effect of CBD on head and neck squamous cell carcinoma (HNSCC) remains unclear. The cytotoxicity of CBD on HNSCC was analyzed using cell survival and colony-forming assays in v
Autor:
Anthony J. Ricci, Z Jason Qian
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Current clinical interest lies in the relationship between hearing loss and cognitive impairment. Previous work demonstrated that noise exposure, a common cause of sensorineural hearing loss (SNHL), leads to cognitive impairments in mice. However, in