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Autor:
Hongli Li, Ruijun Feng, Chonggao Yin, Yuanhang Zheng, Lihong Shi, Wenhao Wang, Zhimei Sheng, Chong Hao, Qinpei Xiao, Ziqian Yan, Baogang Zhang, Hao Luo
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Studies have shown that cancer-associated fibroblasts (CAFs) play an irreplaceable role in the occurrence and development of tumors. Therefore, exploring the action and mechanism of CAFs on tumor cells is particularly important. In this study, we com
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
While long noncoding RNAs (lncRNAs) have been reported to play an important role in human cancer types, they remain poorly understood in papillary thyroid carcinoma (PTC). The aim of this study was to use genome-wide expression profiling to identify
Publikováno v:
Experimental and Molecular Medicine, Vol 53, Iss 11, Pp 1792-1806 (2021)
Experimental & Molecular Medicine
Experimental & Molecular Medicine
In vitro fertilization (IVF) increases the risk of tumorigenesis in offspring. The increased oxidative damage during IVF may be involved in tumor formation. However, the molecular mechanisms underlying this phenomenon remain largely unclear. Using a
Autor:
Wen-Jie Luo, Dingwei Ye, Yongqiang Huang, Yuan-Yuan Qu, Wenhao Xu, Mengfei Yao, Jun Wang, Chunguang Ma, Yiping Zhu, Hailiang Zhang, Fangning Wan
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and development in bladder cancer. However, the underlying molecular mechanisms remain elusive. We previously identified a novel lncRNA signature related to immunity and prog
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
STEAP3 (Six-transmembrane epithelial antigen of the prostate 3, TSAP6, dudulin-2) has been reported to be involved in tumor progression in human malignancies. Nevertheless, how it participates in the progression of human cancers, especially HCC, is s
Autor:
Ming Shen, Haiting Dai, Runming Wang, Lixin Xie, Suhong Zhang, Hanyu Wu, Ye Hu, Wenya Li, Yiming Xing
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Transmembrane protein (TMEM) is a family of protein that spans cytoplasmic membranes and allows cell–cell and cell–environment communication. Dysregulation of TMEMs has been observed in multiple cancers. However, little is known about TMEM116 in
Autor:
Sara Hultberg, Kurt Wahlstedt, Margareta Reis, Jörgen Rosén, Kristoffer N.T. Månsson, Olof R. Hjorth, Malin Gingnell, Vanda Faria, Andreas Frick, Johanna M. Hoppe, Mark Lubberink, Mats Fredrikson, Iman Alaie, Tomas Furmark, Gunnar Antoni, My Jonasson
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Translational Psychiatry
Translational Psychiatry
It has been extensively debated whether selective serotonin reuptake inhibitors (SSRIs) are more efficacious than placebo in affective disorders, and it is not fully understood how SSRIs exert their beneficial effects. Along with serotonin transporte
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Expounding the heterogeneity for ovarian cancer (OC) with the cognition in developmental biology might be helpful to search for robust prognostic markers and effective treatments. In the present study, we employed single-cell RNA-seq with ovarian can
Autor:
Zhili Ren, Ligong Lu, Xiaohong Li, Wei Ge, Chon Lok Lei, Weiwei Liu, Xiangyu Yang, Meixiao Zhan, Chengcheng Song, Dongjin Wang, Nana Ai, Jiaxian Wang, Yang Yang, Guokai Chen, Ya Meng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Nicotinamide, the amide form of Vitamin B3, is a common nutrient supplement that plays important role in human fetal development. Nicotinamide has been widely used in clinical treatments, including the treatment of diseases during pregnancy. However,
Identification of histone methyltransferase NSD2 as an important oncogenic gene in colorectal cancer
Autor:
Zhi-Jun Huang, Jing-jing Lu, Quan Li, Lihao Zhao, Gang Li, Fang Wu, Xiaohua Zhang, Mi-Xue Sun
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Colorectal cancer (CRC) is the second common cause of cancer-related human mortalities. Dysregulation of histone 3 (H3) methylation could lead to transcriptional activation of multiple oncogenes, which is closely associated with CRC tumorigenesis and