Zobrazeno 1 - 10
of 142
pro vyhledávání: ''
Autor:
Xiaoping Li, Wenwen Wang, Yu Shao, Ji Zhou, Jiaqi Huang, Fei Xu, Xiu Gao, Mengyun Wu, Yongli Dong, Wenyan Wu, Jiamin Cai, Junyao Wang, Yunfei Ye, Zhengrong Chen, Chuangli Hao, Yi Yang, Jinping Zhang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 12, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Long non-coding RNAs (lncRNAs) play a crucial role in macrophage development but little is known about their role in asthma. Here, we investigated the role of lncRNA lncTRPM2-AS in asthma and found that lncTRPM2-AS participates in the promotion of ma
Autor:
Xin Wang, Longyan Yang, Bin Cao, Ruili Yin, Lingling Wei, Jing Ke, Li-Jie Zhang, Dong Zhao, Yan Wang, Ying-Jun Zhu
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery
Cell Death Discovery
As a common chronic metabolic disease, the development of diabetes mellitus (DM) may also be accompanied by liver damage and inflammatory disorders. Sitagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP4, also known as CD26), which is clinically
Autor:
Feng Xinxin, Hailin Jia, Dongxiao Cai, Jing Wang, Huanlong Liu, Diandong Jiang, Bo Han, Li Zhang, Wei Sun
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-18 (2021)
Cell Death & Disease
Cell Death & Disease
Myocarditis (MC) is a common, potentially life-threatening inflammatory disease of the myocardium. A growing body of evidence has shown that mitogen-activated protein kinase 14 (MAPK14) participates in the pathogenesis of MC. However, the upstream re
Autor:
Alexei Verkhratsky, Peter Illes, Na Xie, Zhao Huang, Yong Tang, Beáta Sperlágh, Shu-Guang Yu, Francesco Di Virgilio, Henning Ulrich, Alexey Semyanov, Canhua Huang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-20 (2021)
Signal Transduction and Targeted Therapy
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Signal Transduction and Targeted Therapy
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Purines and their derivatives, most notably adenosine and ATP, are the key molecules controlling intracellular energy homoeostasis and nucleotide synthesis. Besides, these purines support, as chemical messengers, purinergic transmission throughout ti
Autor:
Wan Seok Kang, Meeyoung Cho, Hye-jin Kang, Goo Taeg Oh, Mi Ra Kim, Hyang Hee Cho, Bo Gyeong Kang, Soo Yeon Lim, Youngkeun Ahn, Ju Hee Jun, Yong Sook Kim, Hye yun Jeong, Dong Im Cho
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
Resistin-like alpha (Retnla) is a member of the resistin family and known to modulate fibrosis and inflammation. Here, we investigated the role of Retnla in the cardiac injury model. Myocardial infarction (MI) was induced in wild type (WT), Retnla kn
Autor:
Yonggang Ma, Jia Li, Shiqing Liu, Yan Zhou, Ming Deng, Zhonghui Chen, Yubiao Zhang, Yaming Li, Jianghua Ming, Bochun Li
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-15 (2021)
Cell Death Discovery
Cell Death Discovery
MicroRNAs (miRNAs) encapsulated within exosomes can serve as essential regulators of intercellular communication and represent promising biomarkers of several aging-associated disorders. However, the relationship between exosomal miRNAs and osteoarth
Publikováno v:
Cell Death and Disease, Vol 12, Iss 2, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Fulminant hepatitis (FH) is an incurable clinical syndrome where novel therapeutics are warranted. Withaferin A (WA), isolated from herb Withania Somnifera, is a hepatoprotective agent. Whether and how WA improves D-galactosamine (GalN)/lipopolysacch
Publikováno v:
Scientific Reports. 12(1)
Coronary artery disease (CAD) is a long-lasting inflammatory disease characterized by monocyte migration into the vessel wall leading to clinical events like myocardial infarction (MI). However, the role of monocyte subsets, especially their miRNA-dr
Autor:
Xiaohua Gong, Rongrong Le, Xiaojun Chen, Ke Xu, Shi Yujuan, Hongjin Chen, Xiaozhong Huang, Zimiao Chen, Gu Xuemei, Qihan Zhu, Feixia Shen, Chen Xiong
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigated the ef
Autor:
Jie-hui Tan, Jia Xu, Guo-wei Zhang, Yang-chen Jin, Min Luo, Xue-mei Chen, Jun-ling Zeng, Lei Zhou, Shu-ji Li, Rong-chang Cao, Guo-dong Hu, Jin Jin, Jia-yu Lin, Zhao-chang Qi, Huo-ji Chen, Zhi-tao Zhou
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
Treatment of acute pancreatitis (AP) and chronic pancreatitis (CP) remains problematic due to a lack of knowledge about disease-specific regulatory targets and mechanisms. The purpose of this study was to screen proteins related to endoplasmic reticu