Zobrazeno 1 - 10
of 671
pro vyhledávání: ''
Autor:
Salvatore Sciacchitano, Arianna Di Napoli, Benjamin Terrier, Carlo Capalbo, Frauke Goeman, Francesca De Nicola, Michela D'Ascanio, Alberto Ricci, Christian Napoli, Simona di Martino, Giulia Piaggio, Agostino Tafuri, Andrea Sacconi, Maurizio Fanciulli, Luisa de Latouliere, Darragh Duffy, Luciano De Biase, Andrea Negro, Valentina Salvati, Claudia De Vitis, Carla Mottini, Rita Mancini, Francesca Paolini, Giovanni Blandino, Paolo Anibaldi, Paolo Marchetti, Gennaro Ciliberto
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-14 (2021)
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2021, 12 (11), pp.1019. ⟨10.1038/s41419-021-04299-y⟩
Cell Death and Disease, 2021, 12 (11), pp.1019. ⟨10.1038/s41419-021-04299-y⟩
Cell Death & Disease
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2021, 12 (11), pp.1019. ⟨10.1038/s41419-021-04299-y⟩
Cell Death and Disease, 2021, 12 (11), pp.1019. ⟨10.1038/s41419-021-04299-y⟩
Cell Death & Disease
Clinical outcomes of COVID-19 patients are worsened by the presence of co-morbidities, especially cancer leading to elevated mortality rates. SARS-CoV-2 infection is known to alter immune system homeostasis. Whether cancer patients developing COVID-1
Autor:
Shengnan Yang, Ziyang Hong, Qinglin Tan, Jinke Zhuge, Qiang Zuo, Xuxian Zhong, Jing Guo, Qiong Deng, Jiaqi Liao
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Trastuzumab resistance negatively influences the clinical efficacy of the therapy for human epidermal growth factor receptor 2 (HER2) positive gastric cancer (GC), and the underlying mechanisms remain elusive. Exploring the mechanisms and finding eff
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Pyruvate kinase M2 as a key rate-limiting enzyme in glycolysis, it plays a critical role in metabolic reprogramming and carcinogenesis. However, whether PKM2 can promote immunosuppressive microenvironment formation remains unknown in head and neck sq
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it remains a top priority. Drug-induced mitochondrial apoptotic priming, measured by dynamic BH3 profiling (DBP), has been shown in multiple
Autor:
Zhigang Zhang, Zhihuang Zheng, Zhonghua Zhao, Huijuan Wu, Chuanlei Li, Jun Liu, Guangze Shao, Kexin Xu, Jinqing Li
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-13 (2021)
Cell Death & Disease
Cell Death & Disease
Acute kidney injury (AKI) is associated with significant morbidity and its chronic inflammation contributes to subsequent chronic kidney disease (CKD) development. Yes-associated protein (YAP), the major transcriptional coactivator of the Hippo pathw
Autor:
Song Wu, Anli Yang, Cheng Peng, Shunling Ou, Xing Li, Zhongying Huang, Lewei Zhu, Peng Liu, Fu Peng, Yanan Kong
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Melatonin has been reported to have tumor-suppressive effects via comprehensive molecular mechanisms, and long non-coding RNAs (lncRNAs) may participate in this process. However, the mechanism by which melatonin affects the function of lncRNAs in tri
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Afatinib, a second-generation tyrosine kinase inhibitor (TKI), exerts its antitumor effects in head and neck squamous cell carcinoma (HNSCC) by inducing intrinsic apoptosis through suppression of mTORC1. However, the detailed mechanism and biological
Autor:
Xiaoyuan Chu, Mengxi Huang, Xiaolong Liu, Jialong Zhu, Yadi Huang, Chao Liu, Gongbo Fu, Yanyan Chen, Zengjie Lei
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
Alternative splicing (AS) is an important event that contributes to posttranscriptional gene regulation. This process leads to several mature transcript variants with diverse physiological functions. Indeed, disruption of various aspects of this mult
Autor:
Chuanyin Li, Taowei Yang, Kaihui Wu, Xiao Tan, Zixian Wang, Jianming Lu, Xiangming Mao, Zining Long, Chuanfan Zhong, Weibo Zhong, Shuo Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Prostate cancer (PCa) is a common high-incidence malignancy in men, some of whom develop biochemical recurrence (BCR) in the advanced stage. However, there are currently no accurate prognostic indicators of BCR in PCa. The aim of our study was to ide
Autor:
Jing Ji, Yue Li, Bin Liu, Xiaotian Huang, Mei Ji, Zhao Zhao, Wei Liu, Zhe Li, Kaige Wang, Penglin Xu, Jia Shi
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Heterogeneous nuclear ribonucleoprotein L (hnRNPL) is a type of RNA binding protein that highly expressed in a variety of tumors and plays a vital role in tumor progression. However, its post-translational regulation through ubiquitin-mediated proteo