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Autor:
Salvatore Sciacchitano, Arianna Di Napoli, Benjamin Terrier, Carlo Capalbo, Frauke Goeman, Francesca De Nicola, Michela D'Ascanio, Alberto Ricci, Christian Napoli, Simona di Martino, Giulia Piaggio, Agostino Tafuri, Andrea Sacconi, Maurizio Fanciulli, Luisa de Latouliere, Darragh Duffy, Luciano De Biase, Andrea Negro, Valentina Salvati, Claudia De Vitis, Carla Mottini, Rita Mancini, Francesca Paolini, Giovanni Blandino, Paolo Anibaldi, Paolo Marchetti, Gennaro Ciliberto
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-14 (2021)
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2021, 12 (11), pp.1019. ⟨10.1038/s41419-021-04299-y⟩
Cell Death and Disease, 2021, 12 (11), pp.1019. ⟨10.1038/s41419-021-04299-y⟩
Cell Death & Disease
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2021, 12 (11), pp.1019. ⟨10.1038/s41419-021-04299-y⟩
Cell Death and Disease, 2021, 12 (11), pp.1019. ⟨10.1038/s41419-021-04299-y⟩
Cell Death & Disease
Clinical outcomes of COVID-19 patients are worsened by the presence of co-morbidities, especially cancer leading to elevated mortality rates. SARS-CoV-2 infection is known to alter immune system homeostasis. Whether cancer patients developing COVID-1
Autor:
Ben Liu, Yufan Ying, Xueyou Ma, Xiao Wang, Xiangyi Zheng, Weiyu Wang, Liping Xie, Bo Xie, Haiyun Xie, Jiangfeng Li, Jian Wu, Jiajie Fang, Shiming Chen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Emerging discoveries of dynamic and reversible N6-methyladenosine (m6A) modification on RNA in mammals have revealed the key roles of the modification in human tumorigenesis. As known m6A readers, insulin-like growth factor 2 mRNA-binding proteins (I
Autor:
Shengnan Yang, Ziyang Hong, Qinglin Tan, Jinke Zhuge, Qiang Zuo, Xuxian Zhong, Jing Guo, Qiong Deng, Jiaqi Liao
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Trastuzumab resistance negatively influences the clinical efficacy of the therapy for human epidermal growth factor receptor 2 (HER2) positive gastric cancer (GC), and the underlying mechanisms remain elusive. Exploring the mechanisms and finding eff
Autor:
Xiaoyuan Chu, Mengxi Huang, Xiaolong Liu, Jialong Zhu, Yadi Huang, Chao Liu, Gongbo Fu, Yanyan Chen, Zengjie Lei
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-16 (2021)
Cell Death & Disease
Cell Death & Disease
Alternative splicing (AS) is an important event that contributes to posttranscriptional gene regulation. This process leads to several mature transcript variants with diverse physiological functions. Indeed, disruption of various aspects of this mult
Autor:
Benkui Zou, Chao Zhang, Jiasheng Bian, Guo Renbo, Mingshan Yang, Wang Huansheng, Qian Zhou, Zhonghua Xu, Yiran Liang, Jian Xu, Tao Chen, Fajun Pei
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Renal cell carcinoma is the second malignant tumors in the urinary system with high mortality and morbidity. Increasing evidence suggests that long non-coding RNAs (lncRNAs) play critical roles in tumor development and progression. In the current stu
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery
Cell Death Discovery
p53 and NF-κBp65 are essential transcription factors (TFs) in the cellular response to stress. Two signaling systems can often be entwined together and generally produce opposing biological outcomes in a cell context-dependent manner. Inhibitor of a
Autor:
Kailun Xu, Lijun Zhu, Xueping Xiang, Qian Liu, Lijuan Guo, Jimin Shao, Meng Lou, Lingdan Xie, Yongfeng Ding, Chen Li, Hongyan Qi, Jing Shen, Boning Hai, Rui Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Ribonucleotide reductase (RR) is a unique enzyme for the reduction of NDPs to dNDPs, the building blocks for DNA synthesis and thus essential for cell proliferation. Pan-cancer profiling studies showed that RRM2, the small subunit M2 of RR, is abnorm
Autor:
Jianping Zhang, Tian Zhan, Haojun Yang, Fan Li, Yi Dai, Yuwen Jiao, Yunwei Xia, Liming Tang, Guoguang Wang, Hanyang Liu
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Cell Death Discovery
Cell Death Discovery
Platinum drug treatment is one of the most predominant chemotherapeutic strategies for patients with gastric cancer (GC). However, the therapeutic effect is less than satisfactory, largely due to the acquired resistance to platinum drugs. Therefore,
Autor:
Mengyuan Niu, Li Li, Yibing Ding, Lulu Wei, Wangsen Cao, Wenyuan Pu, Zhonglan Su, Shiyu Song, Qian Gao, Hongwei Wang, Chen Zhao, Junaid Wazir
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Cancer cachexia is a multifactorial metabolic syndrome that causes up to 20% of cancer-related deaths. Muscle atrophy, the hallmark of cancer cachexia, strongly impairs the quality of life of cancer patients; however, the underlying pathological proc
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery
Cell Death Discovery
Lung adenocarcinoma (LUAD) remains the most common deadly disease and has a poor prognosis. Pyroptosis could regulate tumour cell proliferation, invasion, and metastasis, thereby affecting the prognosis of cancer patients. However, the role of pyropt