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Autor:
Xiaohua Gong, Rongrong Le, Xiaojun Chen, Ke Xu, Shi Yujuan, Hongjin Chen, Xiaozhong Huang, Zimiao Chen, Gu Xuemei, Qihan Zhu, Feixia Shen, Chen Xiong
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Diabetic nephropathy (DN) as a global health concern is closely related to inflammation and oxidation. Isoliquiritigenin (ISL), a natural flavonoid compound, has been demonstrated to inhibit inflammation in macrophages. Herein, we investigated the ef
Autor:
Jie-hui Tan, Jia Xu, Guo-wei Zhang, Yang-chen Jin, Min Luo, Xue-mei Chen, Jun-ling Zeng, Lei Zhou, Shu-ji Li, Rong-chang Cao, Guo-dong Hu, Jin Jin, Jia-yu Lin, Zhao-chang Qi, Huo-ji Chen, Zhi-tao Zhou
Publikováno v:
Cell Death and Disease, Vol 11, Iss 11, Pp 1-13 (2020)
Cell Death & Disease
Cell Death & Disease
Treatment of acute pancreatitis (AP) and chronic pancreatitis (CP) remains problematic due to a lack of knowledge about disease-specific regulatory targets and mechanisms. The purpose of this study was to screen proteins related to endoplasmic reticu
Autor:
Xuetao Cao, Ye Zhou, Suyuan Wang, Zhenyang Li, Nan Li, Jin Hou, Mu Wang, Kaiwei Jia, Yizhi Yu, Liyuan Zhang
Publikováno v:
Oncogenesis, Vol 9, Iss 10, Pp 1-14 (2020)
Oncogenesis
Oncogenesis
Hepatic apoptosis and the initiated liver inflammation play the initial roles in inflammation-induced hepatocarcinogenesis. Molecular mechanisms underlying the regulation of hepatocyte apoptosis and their roles in hepatocarcinogenesis have attracted
Autor:
Watcharamat Muangkaew, Kanchana Kengkoom, Passanesh Sukphopetch, Sumate Ampawong, Tapanee Kanjanapruthipong, Theerapong Buaban, Pornanong Aramwit
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Psoriasis is mainly caused because of inappropriate immune responses in the epidermis. Rice (Oryza sativa L.: SRNC05053-6-2) consists of anthocyanin, which exhibits strong antioxidative and anti-inflammatory properties. This study aimed to evaluate t
Autor:
Yijian Li, Xiangfeng Liu, Guangdi Li, Huiling Li, Jian Pan, Bohao Liu, Yunchang Yuan, Xiaozhou Li, Peilin Zheng, Xudong Xiang, Xiangping Chai, Zhengyu Peng, Zhibiao He, Feng Liu, Hongliang Zhang, Dongshan Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Recent studies have reported that upregulation of disulfide-bond A oxidoreductase-like protein (DsbA-L) prevented lipid-induced renal injury in diabetic nephropathy (DN). However, the role and regulation of proximal tubular DsbA-L for renal tubuloint
Autor:
Francis Migneault, Alexandre Brodeur, Nicolas Thibodeau, Mélanie Dieudé, Marie-Pierre Hardy, Deborah Beillevaire, Claude Perreault, Julie Turgeon, Marie-Josée Hébert
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Persistent endothelial injury promotes maladaptive responses by favoring the release of factors leading to perturbation in vascular homeostasis and tissue architecture. Caspase-3 dependent death of microvascular endothelial cells leads to the release
Autor:
Youn-Ho Lee, Jina Oh, Young-Joon Lee, Sae-Kwang Ku, Phil Hyun Song, Choong-Gon Kim, Dae-Geon Lee, Chang-Hyun Song
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Balneotherapy is a common non-pharmacological treatment for osteoarthritis (OA), however, the efficacy is controversial in knee OA. Jeju magma-seawater (JMS) has high contents of various minerals, which has anti-inflammatory and antioxidant propertie
Autor:
Olga Stenina-Adognravi, Edward F. Plow, Dmitry Solovjev, Irene Krukovets, Dmitriy Verbovetskiy, Chioma Obiako, Jiahui Wu, Mohammed Tanjimur Rahman, Santoshi Muppala
Publikováno v:
Cell Death and Disease, Vol 11, Iss 1, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Thrombospondin-4 (TSP-4) attracted renewed attention recently as a result of assignment of new functions to this matricellular protein in cardiovascular, muscular, and nervous systems. We have previously reported that TSP-4 promotes local vascular in
Autor:
Qiaona Niu, Ying Liao, Cuiping Song, Chan Ding, Chunchun Meng, Yanrong Li, Lei Tan, Xusheng Qiu, Sun Yingjie, Weiyu Jiang
Publikováno v:
Cell Death and Disease, Vol 10, Iss 12, Pp 1-15 (2019)
Cell Death & Disease
Cell Death & Disease
Newcastle disease virus (NDV) causes severe infectious disease in poultry and selectively kills tumor cells, by inducing apoptosis and cytokines secretion. In this report, we study the mechanisms underlying NDV-induced apoptosis by investigating the
Autor:
Irene Romayor, Alba Herrero, Bård Smedsrød, Beatriz Arteta, Aitor Benedicto, Joana Marquez, Elvira Olaso
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Addi. Archivo Digital para la Docencia y la Investigación
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Scientific Reports
Addi. Archivo Digital para la Docencia y la Investigación
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Scientific Reports
The prometastatic stroma generated through tumor cells/host cells interaction is critical for metastatic growth. To elucidate the role of ICAM-1 on the crosstalk between tumor and primary liver sinusoidal endothelial cells (LSECs) and hepatic stellat