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Autor:
Henny J. M. Beckers, Hellen C S Römkens, Tos T. J. M. Berendschot, Carroll A.B. Webers, Jan S. A. G. Schouten
Publikováno v:
Eye, 36, 167-174. Nature Publishing Group
Eye (Lond)
Eye, 36(1), 167-174. Nature Publishing Group
Eye (Lond)
Eye, 36(1), 167-174. Nature Publishing Group
PURPOSE: To assess the usefulness of water drinking test and dark room provocative testing (WDT + DRPT) in current clinical practice by evaluating input parameters from Swept-source Optical Coherence Tomography (SS-OCT) images, and to determine if cl
Autor:
Gordon D. Waiter, Claire Green, Mathew A. Harris, J. Douglas Steele, Anca-Larisa Sandu, Joanna M. Wardlaw, David J. Porteous, Heather C. Whalley, Liana Romaniuk, Emma L. Hawkins, Rebecca M. Reynolds, Xueyi Shen, Miruna C. Barbu, Aleks Stolicyn, Jonathan R. Seckl, Andrew M. McIntosh, Stephen M. Lawrie, Jonathan Cavanagh, Archie Campbell
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry
Green, C, Stolicyn, A, Harris, M A, Shen, X, Romaniuk, L, Barbu, M C, Hawkins, E L, Wardlaw, J M, Steele, J D, Waiter, G D, Sandu, A, Campbell, A, Porteous, D J, Seckl, J R, Lawrie, S M, Reynolds, R M, Cavanagh, J, Mcintosh, A M & Whalley, H C 2021, ' Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland ', Translational Psychiatry, vol. 11, no. 1 . https://doi.org/10.1038/s41398-021-01644-9
Translational Psychiatry
Green, C, Stolicyn, A, Harris, M A, Shen, X, Romaniuk, L, Barbu, M C, Hawkins, E L, Wardlaw, J M, Steele, J D, Waiter, G D, Sandu, A, Campbell, A, Porteous, D J, Seckl, J R, Lawrie, S M, Reynolds, R M, Cavanagh, J, Mcintosh, A M & Whalley, H C 2021, ' Hair glucocorticoids are associated with childhood adversity, depressive symptoms and reduced global and lobar grey matter in Generation Scotland ', Translational Psychiatry, vol. 11, no. 1 . https://doi.org/10.1038/s41398-021-01644-9
Hypothalamic–pituitary–adrenal (HPA) axis dysregulation has been commonly reported in major depressive disorder (MDD), but with considerable heterogeneity of results; potentially due to the predominant use of acute measures of an inherently varia
Autor:
Froukje Vanweert, Dennis O. Mook-Kanamori, Esther Phielix, Renée de Mutsert, Patrick Schrauwen, Frits R. Rosendaal, Hildo J. Lamb, Sebastiaan C. Boone, Bram Brouwers, Matthijs K. C. Hesselink, Vera B. Schrauwen-Hinderling
Publikováno v:
International Journal of Obesity (2005)
International Journal of Obesity, 45(7), 1510-1520. Nature Publishing Group
International Journal of Obesity, 45(7), 1510-1520. SPRINGERNATURE
International Journal of Obesity, 45(7), 1510-1520. Nature Publishing Group
International Journal of Obesity, 45(7), 1510-1520. SPRINGERNATURE
Aims To evaluate whether the association between plasma branched-chain amino acids (BCAA) and intrahepatic lipid (IHL) was affected by physical activity level. Furthermore, to investigate if a conventional exercise training program, a subcategory of
Autor:
Yucai Wang, Arushi Khurana, Thomas M. Habermann, Jose C. Villasboas, Brian K. Link, William R. Macon, Stephen M. Ansell, Matthew J. Maurer, Raphael Mwangi, James R. Cerhan, Rebecca L. King, Christopher Strouse, Grzegorz S. Nowakowski, Thomas E. Witzig
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 7, Pp 1-6 (2021)
Blood Cancer Journal
Blood Cancer Journal
Immediate treatment for asymptomatic, low-tumor burden follicular lymphoma (FL) has not shown an overall survival benefit over “watch and wait” (W/W) strategy. We estimated incidence of treatment initiation at specific time points and assessed it
Autor:
Jia-Ying Wu, Yi Xiao, Yicheng Zhang, Jianfeng Zhou, Fankai Meng, Yang Cao, Na Wang, Xiaojian Zhu, Jue Wang, Lifang Huang
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 7, Pp 1-8 (2021)
Blood Cancer Journal
Blood Cancer Journal
Chimeric antigen receptor (CAR) T-cell immunotherapy following autologous stem cell transplantation (ASCT) is a promising method for refractory or relapsed multiple myeloma, but explicit data for central nervous system lymphoma (CNSL) are lacking. He
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-10 (2021)
Cell Death & Disease
Cell Death & Disease
Chemotherapy remains the primary treatment of advanced solid cancer, including lung cancer. However, as first-line treatment, cisplatin-based therapy is restricted by the frequent development of drug resistance. Increasing data showed that the progra
Autor:
Angang Yang, Baile Zuo, Wenjin Xi, Rui Zhang, Wei-Hong Wen, Zhangyan Guo, Lin-Tao Jia, Weimiao Li, Guoxu Zheng
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-15 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Despite the successful use of the humanized monoclonal antibody trastuzumab (Herceptin) in the clinical treatment of human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer, the frequently occurring drug resistance remains to be
Autor:
Yan Zheng, Haoting Sun, Mo Chen, Yuan-Yuan Sheng, Lun-Xiu Qin, Qiongzhu Dong, Xudong Ren, Qin Luo, Bei-Yuan Hu, Yan Geng, Tiantian Zou, Xiao-Mei Gao, Kai-Li Zhang, Chaoqun Wang, Lu-Yu Yang, Shican Yan, Yan Fu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-12 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Intercellular cross-talk plays important roles in cancer progression and metastasis. Yet how these cancer cells interact with each other is still largely unknown. Exosomes released by tumor cells have been proved to be effective cell-to-cell signal m
Autor:
Margaret R. Flanigan, Sarah K. Royse, Rajesh Narendran, Michael L. Himes, Davneet S. Minhas, Meryl A. Butters, Clara J. Stoughton, David P. Cenkner, Brian J. Lopresti, Katelyn M. Kozinski
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Translational Psychiatry
Translational Psychiatry
No in vivo human studies have examined the prevalence of Alzheimer’s disease (AD) neuropathology in individuals with alcohol-use disorder (AUD), although recent research suggests that a relationship between the two exists. Therefore, this study use
Autor:
Senlin Zhao, Congcong Zhu, Long Zhang, Yun Xu, Ye Xu, Yuqin Zhang, Weiqi Sheng, Hongtu Zheng, Weixing Dai
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
UPF1 is proved to dysregulate in multiple tumors and influence carcinogenesis. However, the role of UPF1 in oxaliplatin resistance in colorectal cancer (CRC) remains unknown. In our study, UPF1 is upregulated in CRC in mRNA and protein levels and ove