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Autor:
Mirjam Plantinga, Marjolein Y. Berger, Irene M. van Langen, Erwin Birnie, Kristin M. Abbott, Anneke Lucassen, Adelita V. Ranchor, Juliette Schuurmans, Angela Fenwick
Publikováno v:
Genetics in Medicine
Genetics in Medicine, 23(9), 1761-1768. Nature Publishing Group
Genetics in Medicine, 23(9), 1761-1768. Nature Publishing Group
Purpose: the aim of expanded preconception carrier screening (ECS) is to inform any couple wishing to conceive about their chances of having children with severe autosomal or X-linked recessive conditions. Responsible implementation of ECS as reprodu
Publikováno v:
International Journal of Oral Science, Vol 13, Iss 1, Pp 1-11 (2021)
International Journal of Oral Science
International Journal of Oral Science
Head and neck squamous cell carcinoma (HNSCC), an aggressive malignancy, is characterized by high morbidity and low survival rates with limited therapeutic options outside of regional surgery, conventional cytotoxic chemotherapy, and irradiation. Inc
Autor:
Xueyan Wang, Valentin David, Samantha Neuburg, Claire Gerber, Guillaume Courbon, Emily Lynch, Connor Francis, Myles Wolf, Jodie L. Babitt, Tamara Isakova, Aline Martin
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Bone Research
Bone Research
Bone-produced fibroblast growth factor 23 (FGF23) increases in response to inflammation and iron deficiency and contributes to cardiovascular mortality in chronic kidney disease (CKD). Neutrophil gelatinase-associated lipocalin (NGAL or lipocalin 2;
Autor:
Velthorst E., Mollon J., Murray R. M., de Haan L., Germeys I. M., Glahn D. C., Arango C., van der Ven E., Di Forti M., Bernardo M., Guloksuz S., Delespaul P., Mezquida G., Amoretti S., Bobes J., Saiz P. A., Garcia-Portilla M. P., Santos J. L., Jimenez-Lopez E., Sanjuan J., Aguilar E. J., Arrojo M., Carracedo A., Lopez G., Gonzalez-Penas J., Parellada M., Atbasoglu C., Saka M. C., Ucok A., Alptekin K., Akdede B., Binbay T., Altinyazar V., Ulas H., Yalincetin B., Gumus-Akay G., Beyaz B. C., Soygur H., Cankurtaran E. S., Kaymak S. U., Maric N. P., Mihaljevic M. M., Petrovic S. A., Mirjanic T., Del-Ben C. M., Ferraro L., Gayer-Anderson C., Jones P. B., Jongsma H. E., Kirkbride J. B., La Cascia C., Lasalvia A., Tosato S., Llorca P. -M., Menezes P. R., Morgan C., Quattrone D., Menchetti M., Selten J. -P., Szoke A., Tarricone I., Tortelli A., McGuire P., Valmaggia L., Kempton M. J., van der Gaag M., Riecher-Rossler A., Bressan R. A., Barrantes-Vidal N., Nelson B., McGorry P., Pantelis C., Krebs M. -O., Ruhrmann S., Sachs G., Rutten B. P. F., van Os J., Alizadeh B. Z., van Amelsvoort T., Bartels-Velthuis A. A., Bruggeman R., van Beveren N. J., Luykx J. J., Cahn W., Simons C. J. P., Kahn R. S., Schirmbeck F., van Winkel R., Calem M., Tognin S., Modinos G., Pisani S., Kraan T. C., van Dam D. S., Burger N., Amminger G. P., Politis A., Goodall J., Borgwardt S., Studerus E., Gadelha A., Brietzke E., Asevedo G., Asevedo E., Zugman A., Dominguez-Martinez T., Monsonet M., Cristobal-Narvaez P., Racioppi A., Kwapil T. R., Kazes M., Daban C., Bourgin J., Gay O., Mam-Lam-Fook C., Nordholm D., Rander L., Krakauer K., Glenthoj L. B., Glenthoj B., Gebhard D., Arnhold J., Klosterkotter J., Lasser I., Winklbaur B., Reichenberg A.
Publikováno v:
EU-GEI High Risk Study 2021, ' Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings ', Molecular Psychiatry, vol. 26, no. 8, pp. 4529-4543 . https://doi.org/10.1038/s41380-020-00969-z
Molecular Psychiatry, 26(8), 4529-4543. Nature Publishing Group
Scopus
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Molecular Psychiatry, 26, 4529-4543. Nature Publishing Group
Velthorst, E, Mollon, J, Murray, R M, de Haan, L, Germeys, I M, Glahn, D C, Arango, C, van der Ven, E, Di Forti, M, Bernardo, M, Guloksuz, S, Delespaul, P, Mezquida, G, Amoretti, S, Bobes, J, Saiz, P A, García-Portilla, M P, Santos, J L, Jiménez-López, E, Sanjuan, J, Aguilar, E J, Arrojo, M, Carracedo, A, López, G, González-Peñas, J, Parellada, M, Atbaşoğlu, C, Saka, M C, Üçok, A, Alptekin, K, Akdede, B, Binbay, T, Altınyazar, V, Ulaş, H, Yalınçetin, B, Gümüş-Akay, G, Beyaz, B C, Soygür, H, Cankurtaran, E Ş, Kaymak, S U, Maric, N P, Mihaljevic, M M, Petrovic, S A, Mirjanic, T, Del-Ben, C M, Ferraro, L, Gayer-Anderson, C, Jones, P B, Nordholm, D, Glenthøj, B & EU-GEI High Risk Study 2021, ' Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings ', Molecular Psychiatry, vol. 26, pp. 4529–4543 . https://doi.org/10.1038/s41380-020-00969-z
Molecular psychiatry, 26(8), 4529-4543. Nature Publishing Group
Molecular Psychiatry, 26(8), 4529-4543. Nature Publishing Group
Scopus
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Molecular Psychiatry, 26, 4529-4543. Nature Publishing Group
Velthorst, E, Mollon, J, Murray, R M, de Haan, L, Germeys, I M, Glahn, D C, Arango, C, van der Ven, E, Di Forti, M, Bernardo, M, Guloksuz, S, Delespaul, P, Mezquida, G, Amoretti, S, Bobes, J, Saiz, P A, García-Portilla, M P, Santos, J L, Jiménez-López, E, Sanjuan, J, Aguilar, E J, Arrojo, M, Carracedo, A, López, G, González-Peñas, J, Parellada, M, Atbaşoğlu, C, Saka, M C, Üçok, A, Alptekin, K, Akdede, B, Binbay, T, Altınyazar, V, Ulaş, H, Yalınçetin, B, Gümüş-Akay, G, Beyaz, B C, Soygür, H, Cankurtaran, E Ş, Kaymak, S U, Maric, N P, Mihaljevic, M M, Petrovic, S A, Mirjanic, T, Del-Ben, C M, Ferraro, L, Gayer-Anderson, C, Jones, P B, Nordholm, D, Glenthøj, B & EU-GEI High Risk Study 2021, ' Cognitive functioning throughout adulthood and illness stages in individuals with psychotic disorders and their unaffected siblings ', Molecular Psychiatry, vol. 26, pp. 4529–4543 . https://doi.org/10.1038/s41380-020-00969-z
Molecular psychiatry, 26(8), 4529-4543. Nature Publishing Group
The European Community’s Seventh Framework Programme under grant agreement No. HEALTH-F2-2010-241909 (EUGEI); The Spanish sample was supported by the Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III (SAM16PE07CP1, PI16/0201
Autor:
Shengnan Yang, Ziyang Hong, Qinglin Tan, Jinke Zhuge, Qiang Zuo, Xuxian Zhong, Jing Guo, Qiong Deng, Jiaqi Liao
Publikováno v:
Cell Death and Disease, Vol 12, Iss 7, Pp 1-14 (2021)
Cell Death & Disease
Cell Death & Disease
Trastuzumab resistance negatively influences the clinical efficacy of the therapy for human epidermal growth factor receptor 2 (HER2) positive gastric cancer (GC), and the underlying mechanisms remain elusive. Exploring the mechanisms and finding eff
Autor:
David C. Yeomans, Daniel I. Jacobs, Brendan J. Tunstall, Alexander Tzabazis, Dean S. Carson, Mary R. Lee, William H. Frey, Leah R. Hanson
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Translational Psychiatry
Translational Psychiatry
There is evidence of the therapeutic potential of intranasal oxytocin for the treatment of pain and various psychiatric disorders, however, there is scant evidence that oxytocin reaches the brain. We quantified the concentration and distribution patt
Publikováno v:
Light: Science & Applications, Vol 10, Iss 1, Pp 1-12 (2021)
Light, Science & Applications
Light, Science & Applications
Light field microscopy (LFM) has been widely used for recording 3D biological dynamics at camera frame rate. However, LFM suffers from artifact contaminations due to the illness of the reconstruction problem via naïve Richardson–Lucy (RL) deconvol
Autor:
Guo-Dong Zhu, Jiewen Zhang, Feng-Min Shao, Guo-Long Liu, Hong-Mei Zheng, Jing Yu, Yan Chen, Shi Ou-Yang, Mei-Lan Lin, Zheng-Yu Sun
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-9 (2021)
Cell Death & Disease
Cell Death & Disease
Glioblastomas (GBM) is the most common primary malignant brain tumor, and radiotherapy plays a critical role in its therapeutic management. Unfortunately, the development of radioresistance is universal. Here, we identified calcium-regulated heat-sta
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-12 (2021)
Cell Death & Disease
Cell Death & Disease
Conventional chemotherapy is still of great utility in oncology and rationally constructing combinations with it remains a top priority. Drug-induced mitochondrial apoptotic priming, measured by dynamic BH3 profiling (DBP), has been shown in multiple
Autor:
Jiewei Liu, Zihan Qu, Jiang Chen, Lu Li, Xianzhe Yu, Lingling Zhu, Qinghua Zhou, Hong-e Zhang, Li Wang
Publikováno v:
Oncogenesis, Vol 10, Iss 7, Pp 1-12 (2021)
Oncogenesis
Oncogenesis
Several immune checkpoint blockades (ICBs) capable of overcoming the immunosuppressive roles of the tumor immune microenvironment have been approved by the US Food and Drug Administration as front-line treatments of various tumor types. However, due