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pro vyhledávání: '"Pedro R. Lowenstein"'
Autor:
Pedro R. Lowenstein, Patrick Dunn, Maria G. Castro, Padma Kadiyala, Andrea Comba, Phillip E. Kish, Alon Kahana
Publikováno v:
J Vis Exp
Gliomas are primary brain tumors characterized by their invasiveness and heterogeneity. Specific histological patterns such as pseudopalisades, microvascular proliferation, mesenchymal transformation and necrosis characterize the histological heterog
Autor:
Flor M. Mendez, Felipe J Nunez, Rocío I. Zorrilla-Veloz, Maria G. Castro, Pedro R. Lowenstein
Publikováno v:
Journal of Visualized Experiments.
Epigenetic modifications may be involved in the development and progression of glioma. Changes in methylation and acetylation of promoters and regulatory regions of oncogenes and tumor suppressors can lead to changes in gene expression and play an im
Publikováno v:
Journal of Visualized Experiments.
Our laboratory has recently demonstrated that natural killer (NK) cells are capable of eradicating orthotopically implanted mouse GL26 and rat CNS-1 malignant gliomas soon after intracranial engraftment if the cancer cells are rendered deficient in t