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Publikováno v:
Cancer Biomarkers. 16:89-97
Background Chemotherapy-related hepatic dysfunction affected the prognosis of non-small cell lung cancer (NSCLC). However, predictive factors of chemotherapy-related hepatic dysfunction remained undefined. Objective To identify the predictive factors
Autor:
Ting Xu, Bin Yu, Qing Zou, Pu Li, Hai Zhou, Jin Zhou, Changjun Yin, Hongzhou Cai, Xiao Li, Shen Wenyi, Zicheng Xu, Gao Yang, Weizhang Xu
Publikováno v:
Cancer Biomarkers. 16:11-17
OBJECTIVE A functional -94 insertion/deletion polymorphism (rs28362491) in the promoter of the NF-κ B1 gene was reported to influence NF-κ B1 expression and confer susceptibility to different types of cancer. This study aims to determine whether th
Autor:
Manal Mohamed Makhlouf
Publikováno v:
Cancer Biomarkers. 16:181-189
BACKGROUND Abnormalities in the control of apoptosis play an important role in leukemogenesis. Survivin is a member of inhibitor of apoptosis proteins family, it prevents apoptosis by blocking caspase activity and play a role in cell proliferation. W
Autor:
Manoel Odorico de Moraes Filho, Antero Gomes Neto, Guilherme Pinheiro Ferreira da Silva, Herbert Costa, Clarissa Bentes de Araujo Magalhães, Ingrid Correia Nogueira, Israel Lopes Medeiros, Flávia A. Santos, Maria Tereza A. P. Morano, Eanes Delgado Barros Pereira, Amanda Souza Araújo
Publikováno v:
Cancer Biomarkers. 16:47-53
BACKGROUND: Major thoracic surgery is characterized by release of inflammatory markers.The objective of this study was to assess the preoperative and postoperative systemic inflammatory markers of patients undergoing lung cancer resection. METHODS: T
Autor:
Jia Fan, Xuemei Tao, Wenxin Qin, Xisong Huo, Zhouhong Ge, Meilin Qin, Xiaomeng Sun, Juan Yang, Gang Liu, Lei Liu
Publikováno v:
Cancer Biomarkers. 16:161-169
Background It has been shown that circular RNA (circRNA) is associated with human cancers, however, few studies have been reported in hepatocellular carcinoma (HCC). Objective To estimate clinical values of a circular RNA, Hsa_circ_0001649, in HCC. M
Autor:
Deliang Cao, Chenfei Huang, Huai Tao, Fang-Qing Tang, Yi Shen, Fang-guo Lu, Bo Zhang, Yu Cao, Duan-Fang Liao, Yingchun He, Dao-fa Tian, Fangliang Zhou, Lan Song, Li-Mei Lin, Lan He
Publikováno v:
Cancer Biomarkers. 16:127-135
Background Nasopharyngeal carcinoma (NPC) is one of the most common cancers in Southern China. Aldo-keto reductase 1B10 (AKR1B10) is upregulated in multiple tumors and plays an oncogenic role. Objective To examine the expression of AKR1B10 at mRNA an
Publikováno v:
Cancer Biomarkers. 15:909-913
Background The thyroperoxidase (TPO) genetic variants in thyroid carcinoma is scarcely reported. Objective We report on a pedigree of thyroid papillary carcinoma and hypoechoic thyroid nodules with the TPO gene mutations. Methods The compound heteroz
Publikováno v:
Cancer Biomarkers. 15:725-734
Hyperlactatemia with or without type B lactic acidosis is a rare complication of cancer, previously observed most often in hematological malignancies. The aim of this study was to assess the prognostic value of lactic acid (LA) in patients with metas
Autor:
Gerasimos Aravantinos, Dimitrios Pektasides, Maria Gazouli, Theodoros Karantanos, Anna Sioziou, Athina Isaakidou, George Theodoropoulos
Publikováno v:
Cancer Biomarkers. 15:843-850
Background Bevacizumab, an angiogenesis inhibitor is used in regimens for metastatic colorectal cancer (CRC). A minority of cancer cells with characteristics of cancer stem cells (CSC) may be responsible for progression and development of chemotherap
Autor:
Ryuji Suzuki, Yoshiki Hamada, Kazutaka Kitaura, Goro Kaneda, Tomoko Nagaoka, Yukinaga Miyata, Hideki Kanazawa, Satsuki Suzuki, Kenichi Kumagai
Publikováno v:
Cancer Biomarkers. 15:789-797
Background Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, and novel effective treatments and diagnostic tools are urgently required. Objective The selection of appropriate targeting tumor-associated antigens (TAAs) is critical