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Autor:
Giovanni Pierorazio, Francesco Pavese, Giampiero Porzio, Katia Cannita, V. Cocciolone, Lucilla Verna, Silvia Rotondaro, Corrado Ficorella, Tina Sidoni, Alessandro Parisi
Publikováno v:
Breast Disease. 40:257-262
BACKGROUND: Despite the increase in chances of cure for early breast cancer (EBC) patients, approximately 20–45% of them will experience a disease recurrence, particularly bone metastases in 60–80% of cases, which occur more frequently in luminal
Publikováno v:
Breast Disease. 40:177-182
BACKGROUND: Of the most common imaging modalities for breast cancer diagnosis – mammogram (MAM), ultrasound (US), magnetic resonance imaging (MRI) – it has not been well established which of these most accurately corresponds to the histological t
Publikováno v:
Breast Disease. 40:S33-S37
BACKGROUND: Increased plasma aldehyde dehydrogenase 1 (ALDH1) levels have been proposed to predict cancer chemoresistance. However, studies have reported inconsistent results, depending on the type of cancer cells used. OBJECTIVE: This study aimed to
Autor:
Gita Vita Soraya, Prihantono Prihantono, Muhammad Faruk, Salman Ardy Syamsu, John Pieter Junior, Septiman Septiman, Okto Sampe Padang, Elridho Sampepajung
Publikováno v:
Breast Disease. 40:S77-S84
BACKGROUND: Breast cancer, a global health problem with a high mortality rate, has several risk factors, including obesity and increased lipid profile. Postmenopausal obesity is associated with estrogen production from adipose tissue, while abnormal
Autor:
Marcello Ferreti Fanelli, Marcia Torresan Delamain, Fernando Augusto Soares, Carmen Silvia Passos Lima, Angelo Borsarelli Carvalho Brito, Carmino Antonio De Souza, José Vassallo
Publikováno v:
Tumor Biology. 43:129-140
OBJECTIVES: Single nucleotide variants (SNVs) in vascular endothelial growth factor A (VEGFA) and VEGFA receptor (KDR) genes confer different inherited abilities in angiogenesis (AG) pathway. We aimed in the present study to evaluate influence of six
Publikováno v:
Breast Disease. 40:25-31
AIM OF THE STUDY: The microenvironment depicts the relationship between tumour cells and immune response, and every insight into stromal lymphocytes could contribute to explain their role and activity. E26 transformation specific-1 (ETS-1) is a trans
Publikováno v:
Cancer Biomarkers. 21:179-186
PI3K/Akt/mTOR signaling pathway plays an important role in tumor development. mTOR overexpression and PI3K/ Akt/mTOR signaling pathway enhancement were found in endometrial cancer (EC). MiR-101 was found downregulated in EC. Bioinformatics analysis s
Publikováno v:
Cancer Biomarkers. 28:293-299
Background/objective CD133 is the molecular marker of normal stem cells and progenitor cells and also confirmed as a marker for cancer stem cells in various tumors. The aim of this study is to examine the expression of CD133 and assess its clinicopat
Autor:
Nicolas Kuritzky, Robert J. Poppiti, Lydia Howard, Christopher A. Febres-Aldana, Kritika Krishnamurthy
Publikováno v:
Breast Disease. 39:51-59
BACKGROUND Hormone-receptor-negative breast carcinoma (HRNBC), including triple-negative and HER-2 amplified tumors, can overexpress P16INK4a with substantial contribution to tumor progression. In nonneoplastic cells, P16INK4a mediates growth arrest
Autor:
Suk Jung Kim, Young Mi Park
Publikováno v:
Breast Disease. 39:71-83
Background With an aging society, Korean women ≥70 years of age are increasingly being diagnosed with breast cancer. Objective To investigate the clinicopathological and biological characteristics of breast cancer in elderly Korean women and compar