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Autor:
Anne M. Nixon, Craig Horbinski, Nupur K. Das, James R. Connor, Paul L. Fox, Petra Hamerlik, James S. Hale, Tyler E. Miller, David L. Schonberg, Awad Jarrar, Robert T. Karl, Stephen C. Mack, Justin D. Lathia, Bjarne Winther Kristensen, William A. Flavahan, Ann Mari Rosager, Paul J. Tesar, Qiulian Wu, Christopher G. Hubert, Jeremy N. Rich
Publikováno v:
Schonberg, D L, Miller, T E, Wu, Q, Flavahan, W A, Das, N K, Hale, J S, Hubert, C G, Mack, S C, Jarrar, A M, Karl, R T, Rosager, A M, Nixon, A M, Tesar, P J, Hamerlik, P, Kristensen, B W, Horbinski, C, Connor, J R, Fox, P L, Lathia, J D & Rich, J N 2015, ' Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells ', Cancer Cell, vol. 28, no. 4, pp. 441-455 . https://doi.org/10.1016/j.ccell.2015.09.002
Glioblastomas display hierarchies with self-renewing cancer stem-like cells (CSCs). RNA sequencing and enhancer mapping revealed regulatory programs unique to CSCs causing upregulation of the iron transporter transferrin, the top differentially expre