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Autor:
Marko Lilic, Eamonn F. Healy
Publikováno v:
Biochemical and Biophysical Research Communications
The angiotensin Converting Enzyme 2 (ACE2) receptor is a key component of the renin-angiotensin-aldesterone system (RAAS) that mediates numerous effects in the cardiovascular system. It is also the cellular point of contact for the coronavirus spike
Autor:
Yingyi Long, Wang Wang, Aishun Jin, Chao Hu, Shuyi Song, Huajun Zhang, Xiaojian Han, Shenglong Li, Bo Zhang, Feiyang Luo, Yingming Wang, Tingting Li
Publikováno v:
Biochemical and Biophysical Research Communications
Potent neutralizing antibodies (Abs) have been proven with therapeutic efficacy for the intervention against SARS-CoV-2. Majority of these Abs function by directly interfering with the virus entry to host cells. Here, we identified a receptor binding
Publikováno v:
Biochemical and Biophysical Research Communications
A newly-emergent beta-coronavirus, SARS-CoV-2, rapidly has become a pandemic since 2020. It is a serious respiratory disease and caused more than 100 million of deaths in the world. WHO named it COVIA-19 and there is no effective targeted drug for it
Publikováno v:
Biochemical and Biophysical Research Communications
The current COVID-19 pandemic is caused by infections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A sex-bias has been observed, with increased susceptibility and mortality in male compared to female patients. The gene for t
Autor:
Filipe Pereira
Publikováno v:
Biochemical and Biophysical Research Communications
The SARS-CoV-2 Variant of Concern 202012/01 (VOC-202012/01) emerged in southeast England and rapidly spread worldwide. This variant is believed to be more transmissible, with all attention being given to its spike mutations. However, VOC-202012/01 ha
Publikováno v:
Experimental Hematology, 93, 14-24. Elsevier Inc.
B-Cell receptor (BCR) sequencing has been the force driving many recent advances in chronic lymphocytic leukemia (CLL) research. Here, we discuss the general principles, revelations, and applications of reading the BCR immunome in the context of CLL.
Autor:
Luca Fierro, Manisha Balwani, Praveena Narayanan, Nora Nesheiwat, Pramod K. Mistry, Hetanshi Naik
Publikováno v:
Molecular Genetics and Metabolism
SARS-CoV-2 infection carries high morbidity and mortality in individuals with chronic disorders. Its impact in rare disease populations such as Gaucher disease (GD) is unknown. In GD, decreased acid β-glucosidase activity leads to the accumulation o
Publikováno v:
Virology
This study focused on intestinal restitution including phenotype switching of absorptive enterocytes and the abundance of different enterocyte subtypes in weaned pigs after porcine epidemic diarrhea virus (PEDV) infection. At 10 days post-PEDV-inocul
Germ cells develop into eggs and sperms and represent a lineage that survives through multiple generations. Germ cell specification during embryogenesis proceeds through one of two basic modes: either the cell-autonomous mode or the inductive mode. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48dd2af97d534dff67300fb9cf8ba189
http://hdl.handle.net/11577/3419850
http://hdl.handle.net/11577/3419850
Publikováno v:
Experimental Gerontology, 156:111597. Elsevier Inc.
Guan, L, Tuttle, C S L, Reijnierse, E M, Lim, W K & Maier, A B 2021, ' Unresolved inflammation during hospitalization is associated with post-discharge institutionalization and mortality in geriatric rehabilitation inpatients : The RESORT cohort ', Experimental Gerontology, vol. 156, 111597 . https://doi.org/10.1016/j.exger.2021.111597
Guan, L, Tuttle, C S L, Reijnierse, E M, Lim, W K & Maier, A B 2021, ' Unresolved inflammation during hospitalization is associated with post-discharge institutionalization and mortality in geriatric rehabilitation inpatients : The RESORT cohort ', Experimental Gerontology, vol. 156, 111597 . https://doi.org/10.1016/j.exger.2021.111597
Background Inflammation contributes to adverse health outcomes in community-dwelling populations. Little is known about inflammation in hospitalized older adults and its association with adverse outcomes. This study aimed to evaluate the association