Zobrazeno 1 - 10
of 36 498
pro vyhledávání: ''
Autor:
Efthymia Skafida, Meletios-Athanasios Dimopoulos, Kleoniki Apostolidou, Angeliki Rouvalis, Garyfallia Bletsa, Maria Kaparelou, Angeliki Andrikopoulou, F. Zagouri, Konstantinos Koutsoukos, Michalis Liontos
Publikováno v:
International Journal of Gynecologic Cancer. 33:571-576
Background: Immune checkpoint inhibitors (ICIs) have been widely implemented in the treatment of solid tumors. Although epithelial ovarian carcinoma is considered as scarcely immunogenic, the presence of tumor-infiltrating T lymphocytes (TILs) in the
Publikováno v:
BMJ Case Rep
A male term neonate was admitted to the neonatal intensive care unit in the first hours of life with central cyanosis. Echocardiogram showed severe biventricular hypertrophy, markedly right-sided, tricuspid regurgitation, a patent foramen ovale and a
Publikováno v:
European Journal of Hospital Pharmacy. 30:64-69
OBJECTIVES Outpatient parenteral antimicrobial therapy (OPAT) services using continuous infusions (CIs) of antimicrobial agents in elastomeric devices require evidence of acceptable stability of the agent over the infusion period. A period of refrige
Autor:
Caradoc Morris
Publikováno v:
BMJ Supportive & Palliative Care. 12:53-57
Diamorphine is a strong opioid licensed in the UK for many uses, including moderate and severe pain. In the early 2000s, its use in palliative medicine was widespread before a supply disruption led to preferential use of alternative, cheaper opioids.
Autor:
Su-Hyung Park, Eui-Soon Kim, Jin Gu Lee, Yong Joon Lee, Seongjin Choi, Kun Woo Kim, Hyo Sup Shim, Minwoo Jeon, Eui-Cheol Shin, Jae-Ik Lee, Seongju Jeong, Seung Yeon Ha, Galam Leem, Shin Myung Kang
Publikováno v:
Thorax. 77:769-780
BackgroundTumour-unrelated, virus-specific bystander CD8+T cells were recently shown to be abundant among tumour-infiltrating lymphocytes (TILs). However, their roles in tumour immunity have not been elucidated yet.MethodsWe studied the characteristi
Publikováno v:
Thorax. 77:1079-1087
BackgroundLow-dose oral azithromycin therapy is recommended as a preventive treatment for acute exacerbations of COPD. However, the overall benefit–harm balance of this treatment has not been well studied.MethodsA probabilistic Markov model of COPD
Autor:
Daniela Bohr, K. Manger, Bernhard Manger, Georg Schett, Verena Schoenau, Thomas Harrer, Gerhard Krönke, Arnd Kleyer, David Simon, Koray Tascilar, Filippo Fagni, Johannes Knitza, Katja Schmidt, Andreas Ramming
Publikováno v:
Annal of the Rheumatic Diseases
ObjectivesTotestwhether patients with immune-mediated inflammatory disease (IMIDs), who did not respond to two doses of the SARS-CoV-2 vaccine, develop protective immunity, if a third vaccine dose is administered.MethodsPatients with IMID who failed
Autor:
Catherine J. Harmer, Ilina Singh, Ly-Mee Yu, Judit Simon, Paul Harrison, Glyn Lewis, Chloe Edwards, Sophie Roberts, Phil J. Cowen, Jennifer M Rendell, Sheena K. Au-Yeung, James Griffiths, Fiona Chan, Stuart Watson, Rafal Bogacz, Michael Browning, Anthony J. Cleare, Jonathan Evans, Milensu Shanyinde, John R. Geddes, David Kessler, Andrea Cipriani, M J Attenburrow
Publikováno v:
Au-Yeung, S K, Griffiths, J, Roberts, S, Edwards, C, Yu, L-M, Bogacz, R, Rendell, J, Attenburrow, M-J, Watson, S, Chan, F, Cipriani, A, Cleare, A, Harmer, C J, Kessler, D, Evans, J, Lewis, G, Singh, I, Simon, J, Harrison, P J, Cowen, P, Shanyinde, M, Geddes, J & Browning, M 2021, ' PAX-D : study protocol for a randomised placebo-controlled trial evaluating the efficacy and mechanism of pramipexole as add-on treatment for people with treatment resistant depression ', Evidence-Based Mental Health . https://doi.org/10.1136/ebmental-2021-300282
IntroductionClinical depression is usually treated in primary care with psychological therapies and antidepressant medication. However, when patients do not respond to at least two or more antidepressants within a depressive episode, they are conside
Autor:
José Antonio Martínez, Aina Moll-Udina, Ines Hernanz, Alfredo Adán, Gerard Espinosa, Maite Sainz de la Maza, Marina Mesquida, Victor Llorenç
Publikováno v:
British Journal of Ophthalmology. 107:495-499
AimsTo evaluate the clinical characteristics and therapeutic outcome of patients with recurrent scleritis of unknown demonstrable aetiology and positive QuantiFERON-TB Gold In-Tube test (QFT).MethodsRetrospective chart review of the demographic, clin
Autor:
Adam T. Hill, Kerstin Ziegler, Adriano G. Rossi, Donald J. Davidson, Phil D Whitfield, Pallavi Bedi
Publikováno v:
Bedi, P, Zeigler, K, Whitfield, P D, Davidson, D J, Rossi, A G & Hill, A 2021, ' Dysregulation of Prostaglandins, Leukotrienes and Lipoxin A4 in Bronchiectasis ', Thorax . https://doi.org/10.1136/thoraxjnl-2020-216475
IntroductionBronchiectasis is characterised by excessive neutrophilic inflammation. Lipid mediators such as prostaglandins and leukotrienes have crucial roles in the inflammatory response. Further characterisation of these lipids and understanding th