Zobrazeno 131 - 140
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Publikováno v:
European Journal of Hospital Pharmacy. 29:e91-e94
Piperacillin-tazobactam is a broad-spectrum antimicrobial agent that is commonly used in clinical practice. The development of delayed drug hypersensitivity reaction (DHR) has been reported in several cases previously. Here we describe an unusual cas
Autor:
Steven Yeh, Rahul N. Khurana, Pouya Dayani, Lana Rifkin, Milan Shah, Colette Hall, Christopher R. Henry, Mark R Barakat, Robert C Wang, Thomas A. Ciulla
Publikováno v:
British Journal of Ophthalmology. 106:802-806
PurposeTo evaluate local and systemic safety of suprachoroidal (SC) triamcinolone acetonide injectable suspension (CLS-TA) injections in subjects with non-infectious uveitis (NIU).DesignOpen-label, prospective multicentre safety study.ParticipantsThi
Autor:
Teddy Y. Wu, Johannes Kaesmacher, Duncan Wilson, Urs Fischer, David J. Seiffge, Jan C. Purrucker, Thomas Raphael Meinel
Publikováno v:
Seiffge, David J.; Meinel, Thomas; Purrucker, Jan Christoph; Kaesmacher, Johannes; Fischer, Urs; Wilson, Duncan; Wu, Teddy Y (2021). Recanalisation therapies for acute ischaemic stroke in patients on direct oral anticoagulants. Journal of neurology, neurosurgery, and psychiatry, 92(5), pp. 534-541. BMJ Publishing Group 10.1136/jnnp-2020-325456
Journal of Neurology, Neurosurgery, and Psychiatry
Journal of Neurology, Neurosurgery, and Psychiatry
Direct oral anticoagulants (DOACs) have emerged as primary therapeutic option for stroke prevention in patients with atrial fibrillation. However, patients may have ischaemic stroke despite DOAC therapy and there is uncertainty whether those patients
Autor:
Catherine Luedke, Jerald Z. Gong, Lian-He Yang, Yue Zhao, Rachel Jug, Jenna McCracken, Jonathan Galeotti, Jake Maule, Imran Siddiqi, Endi Wang, Chuanyi M. Lu
Publikováno v:
Journal of Clinical Pathology. 75:292-301
AimsMyeloid neoplasms occur in the setting of chronic lymphocytic leukaemia (CLL)/CLL-like disease. The underlying pathogenesis has not been elucidated.MethodsRetrospectively analysed 66 cases of myeloid neoplasms in patients with CLL/CLL-like diseas
Autor:
Katja Giersch, Marc Lütgehetmann, Stephan Urban, Rudolf K. F. Beran, A Pirosu, Tassilo Volz, Maura Dandri, Lena Allweiss, Robert C Muench, Simon P. Fletcher, Hassan Javanbakht
Publikováno v:
Gut
ObjectiveTherapeutic strategies silencing and reducing the hepatitis B virus (HBV) reservoir, the covalently closed circular DNA (cccDNA), have the potential to cure chronic HBV infection. We aimed to investigate the impact of small interferring RNA
Autor:
Robert B. Hufnagel, Raphaela Goldbach-Mansky, Priyam Jani, Edward W. Cowen, Rachael Wasikowski, Antonette Souto El Husny, Marcus Y. Chen, J. Michelle Kahlenberg, Johann E. Gudjonsson, Sayoko E. Moroi, Adriana Almeida de Jesus, Blake M. Warner, Allison C. Billi, Haitao Wang, Izabela Almeida, Brian P. Brooks, Sarah J. Garnai, Lev Prasov, Edmundo Frota de Almeida, Carlos Ferreira, Shahzad I. Mian, Lam C. Tsoi, Julia E. Richards, Brenda L. Bohnsack, Luciana Negrão Frota de Almeida, Fernando Kok, Bin Guan, Sun Hur
Publikováno v:
J Med Genet
BackgroundSingleton-Merten syndrome (SGMRT) is a rare immunogenetic disorder that variably features juvenile open-angle glaucoma (JOAG), psoriasiform skin rash, aortic calcifications and skeletal and dental dysplasia. Few families have been described
Autor:
Ying Wang, Arlene M. Correa, Boyi Gan, Randy L. Johnson, Ailing W. Scott, Cordelia Y Li, Melissa Pool Pizzi, Jeannelyn S. Estrella, Longfei Huo, Shaozhong Wei, Lianchun Xiao, Brian Weston, Namita Shanbhag, Shumei Song, Yuan Li, Wayne L. Hofstetter, Guang Lei, Lang Ma, Jaffer A. Ajani, Manoop S. Bhutani, Bin Liu, Jeffrey H. Lee, Qiongrong Chen, Jiankang Jin
Publikováno v:
Gut
ObjectiveGastro-oesophageal cancers (GEC) are resistant to therapy and lead to poor prognosis. The cancer stem cells (CSCs) and antiapoptotic pathways often confer therapy resistance. We sought to elucidate the antitumour action of a BCL-2 inhibitor,
Autor:
Kyungjoo Cho, June-Young Koh, Ha Seok Lee, Jae Geun Lee, Dong Jin Joo, Soon Il Kim, Jun Yong Park, Ji Won Han, Myoung Soo Kim, Jong Hoon Kim, Min-Seok Rha, Su-Hyung Park, Eui-Cheol Shin
Publikováno v:
Gut. 71:605-615
ObjectiveThe liver acts as a frontline barrier against diverse gut-derived pathogens, and the sinusoid is the primary site of liver immune surveillance. However, little is known about liver sinusoidal immune cells in the context of chronic liver dise
Autor:
Neelufar Mozaffarian, Daniel W. T Ching, Jonathan Kay, Z. Yin, Rene Westhovens, Chantal Tasset, John S. Sundy, Robert Landewé, Gerd R Burmester, Tatsuya Atsumi, William Stohl, Franziska Matzkies, Désirée van der Heijde, William F. C. Rigby, Osvaldo D. Messina, Arvind Chopra, Ying Guo, Beatrix Bartok, Angelika Jahreis
Publikováno v:
Annals of the Rheumatic Diseases
Objectives To investigate efficacy and safety of the Janus kinase-1 inhibitor filgotinib in patients with active rheumatoid arthritis (RA) with limited or no prior methotrexate (MTX) exposure. Methods This 52-week, phase 3, multicentre, double-blind
Autor:
Monique R.M. Jongbloed, Berto J. Bouma, Hubert W. Vliegen, Philippine Kiès, Tjitske E Zandstra, Anastasia D Egorova, Martin J. Schalij, Laurens F. Tops, Marieke Nederend
Publikováno v:
Heart, 107, 1725-1730. BMJ Publishing Group
Heart
Heart, 107(21), 1725-1730. BMJ PUBLISHING GROUP
Heart
Heart, 107(21), 1725-1730. BMJ PUBLISHING GROUP
ObjectivePharmacological options for patients with a failing systemic right ventricle (RV) in the context of transposition of the great arteries (TGA) after atrial switch or congenitally corrected TGA (ccTGA) are not well defined. This study aims to