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Publikováno v:
BMJ. 336:701-704
Objectives To determine and quantify differences in efficacy between treatment regimens for brucellosis. Design Systematic review and meta-analysis of randomised controlled trials assessing different antibiotic regimens and durations of treatment for
Autor:
Barbara Burke, Nathalie Nicolay, Cathy Hewison, Isaac Badi Fursa, Guillaume Grillet, Gerardo Priotto, Manica Balasegaram, Loretxu Pinoges
Publikováno v:
BMJ. 336:705-708
Objective: To assess the safety and effectiveness of eflornithine as first line treatment for human African trypanosomiasis. Design: Cohort study. Setting: Control programme in Ibba, southern Sudan. Participants: 1055 adults and children newly diagno
Publikováno v:
Scopus-Elsevier
British Medical Journal
British Medical Journal
Is monitoring initial response to treatment always helpful in clinical management of patients? Bell and colleagues have developed a framework for deciding whether surrogate outcomes should be used to monitor initial response to treatment in chronic d
Publikováno v:
BMJ. 336:195-198
Objective To determine if there is a relation between aspirin “resistance” and clinical outcomes in patients with cardiovascular disease. Design Systematic review and meta-analysis. Data source Electronic literature search without language restri
Autor:
Jonathon L Simon, Sunit Singhi, Samir K. Saha, Shamim Qazi, Irene Maulen-Radovan, Paul A. Law, Donald M. Thea, Josefina Egas, Salem Banajeh, Rai Asghar, Imran Iqbal, Greta Mino, Fernando Sempértegui, Mathuram Santosham, William B. MacLeod, Patricia L. Hibberd, Zafarullah Kundi, Mary Katep-Bwalya
Publikováno v:
BMJ. 336:80-84
Objective To evaluate whether five days’ treatment with injectable ampicillin plus gentamicin compared with chloramphenicol reduces treatment failure in children aged 2-59 months with community acquired very severe pneumonia in low resource setting
Publikováno v:
BMJ. 335:1248-1251
Objective To evaluate the benefits and harms of antithrombin III in critically ill patients. Design Systematic review and meta-analysis of randomised trials. Data sources CENTRAL, Medline, Embase, International Web of Science, LILACS, the Chinese Bio
Publikováno v:
BMJ. 335:508-512
Many patients with type 2 diabetes are denied treatment with metformin because of “contraindications” such as cardiac failure, which may not be absolute contraindications
Autor:
Paul Aveyard, Robert West
Publikováno v:
BMJ. 335:37-41
Cross sectional studies show that most smokers in countries such as the United Kingdom and the United States report that they want to stop and intend to stop at some point.1 The rate of attempts to stop is high—78 attempts per 100 smokers per year
Autor:
John M. Davison, Roy Taylor
Publikováno v:
BMJ. 334:742-745
Pregnancy in women with type 1 diabetes remains a challenge for the patient and healthcare team alike. The scenario box on this page highlights some of the problems in achieving satisfactory pregnancy outcomes in women with diabetes. We discuss in th
Autor:
Helen Roberts
Publikováno v:
BMJ. 334:736-741
The transition into the menopause usually begins with elongation of cycle length, the term postmenopausal being used after one year with no periods.1 Most women experience menopause between 40 and 58 years of age.1 No menopausal symptom is universal.