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Autor:
Susan A. Greenfield
Publikováno v:
BMJ. 317:1698-1701
People have been using drugs to alter brain states since the dawn of time. But the use of specific drugs to combat specific brain problems is a hallmark of this century. In previous eras doctors reached for laudanum to combat hysteria, oblivious to t
Autor:
V Sainio, Eero Kivilaakso, Ulf-Håkan Stenman, Jari Leinonen, Reijo Haapiainen, Tom Schröder, Esko Kemppainen, J Hedström
Publikováno v:
BMJ. 313:333-337
Objective: To estimate the usefulness of serum concentrations of the complex of trypsin 2 and (alpha)1 antitrypsin in diagnosing and assessing the severity of acute pancreatitis in comparison with serum C reactive protein, amylase, and trypsinogen 2
Autor:
Trevor Baglin
Publikováno v:
BMJ. 312:683-686
Summary points Disseminated intravascular coagulation is primarily a clinical diagnosis, and laboratory tests are used to confirm the diagnosis and monitor replacement of blood components Tests required are platelet count, prothrombin time, activated
Autor:
Joan Austoker
Publikováno v:
BMJ. 309:517-520
Cancer control encompasses the whole spectrum from prevention and early diagnosis to treatment and palliation. The key to the future of cancer control will be to establish multidisciplinary approaches to each type of cancer across this spectrum. For
EDITOR—O'Beirne and Cairns reported a case of cholestatic hepatitis in association with celecoxib.1 This case does not, however, fulfil the accepted international criteria for cholestatic hepatitis as it was not confirmed histologically.2 Biochemic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814e9477d8548098ec153a9bb35e63d7
https://europepmc.org/articles/PMC1122719/
https://europepmc.org/articles/PMC1122719/
Publikováno v:
BMJ. 328:629-630
Phaeochromocytoma, a rare endocrine disorder causing arterial hypertension, is found in less than 0.1% of patients with hypertension.1 The diagnosis is excluded by the repeated finding of normal catecholamine (for example, dopamine) concentrations in
Autor:
Chi K Yeung, Karen S.L. Lam, Annette W.K. Tso, Michele M A Yuen, Chi-Hung Chau, Johnny C. Y. Chan, Wing Sun Chow, Chi Ho Lee
Publikováno v:
BMJ. 344:d8351-d8351
A 59 year old Chinese man was admitted for a blistering eruption. He had stopped using injected drugs and drinking alcohol three years ago after having previously drunk two cans of beer, equivalent to 2-3 units of alcohol, a week. Two years ago, he h
Autor:
Ned Stafford
Publikováno v:
BMJ. 338:a3091-a3091
A decision by Switzerland’s highest court to overturn a doctor’s conviction for failing to treat effectively “several patients” with cancer has been described as “a judicial scandal with disastrous ethical and medical implications” by a p
Autor:
Alison L Jones, Nicholas C. Turner
Publikováno v:
BMJ. 337:a421-a421
Summary points Breast cancer comprises a spectrum of related but different cancer subtypes, which have different causal genetic changes, may follow different clinical courses, and require different treatments tailored to the phenotype (fig 1⇓). Her
Autor:
Lynn Eaton
Publikováno v:
BMJ. 331:1287.2
Healthcare organisations should not rush into using trastuzumab (Herceptin) for early breast cancer without first examining the implications on budgets of doing so, warns a Belgian health economist. Mattias Neyt of Ghent University had carried out an