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Autor:
Alan A. Dombkowski, Larry H. Matherly, Yubin Ge, Jeffrey W. Taub, Yaddanapudi Ravindranath, David L. Becton, Katherine M. LaFiura, Ravikiran S. Yedidi, Gita Massey, Howard J. Weinstein, Steven Buck, Mark Stout, Dana Tatman
Publikováno v:
Blood. 107:1570-1581
Children with Down syndrome (DS) with acute megakaryocytic leukemia (AMkL) have very high survival rates compared with non-DS AMkL patients. Somatic mutations identified in the X-linked transcription factor gene, GATA1, in essentially all DS AMkL cas