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Publikováno v:
Developmental Biology. 498:35-48
Fibroblasts play an important role in maintaining tissue integrity by secreting components of the extracellular matrix and initiating response to injury. Although the function of fibroblasts has been extensively studied in adults, the embryonic origi
Autor:
Jane C Fenelon, Alistair R. Evans, Michael Pyne, Stephen D. Johnston, Neal Anthwal, Abigail S. Tucker, Abbie Bennetts, Marilyn B. Renfree
Publikováno v:
Developmental Biology. 495:8-18
In the short-beaked echidna, Tachyglossus aculeatus, after an initial period of in utero development, the egg is laid in the pouch and incubated for 10 days. During this time, the fetuses develop an egg tooth and caruncle to help them hatch. However,
Autor:
Kwang Wook Min, Namsuk Kim, Jae Hoon Lee, Younghoon Sung, Museong Kim, Eun Jung Lee, Jong-Myeong Kim, Jae-Hyun Kim, Jaeyoung Lee, Wonjin Cho, Jee Myung Yang, Nury Kim, Jaehoon Kim, C. Justin Lee, Young-Gyun Park, Seung-Hee Lee, Han-Woong Lee, Jin Woo Kim
Publikováno v:
Experimental & Molecular Medicine. 55:385-400
In binocular animals that exhibit stereoscopic visual responses, the axons of retinal ganglion cells (RGCs) connect to brain areas bilaterally by forming a commissure called the optic chiasm (OC). Ventral anterior homeobox 1 (Vax1) contributes to the
Publikováno v:
The Journal of Gene Medicine.
Background Prostate cancer (PCa) is a heavy health-threat for human worldwide. Recent studies revealed that microRNAs (miRNAs) are associated with the progression of human cancers, including PCa. However, no study has been performed to investigate th
Autor:
Emily S. Bell, Pragya Shah, Noam Zuela-Sopilniak, Dongsung Kim, Alice-Anais Varlet, Julien L.P. Morival, Alexandra L. McGregor, Philipp Isermann, Patricia M. Davidson, Joshua J. Elacqua, Jonathan N. Lakins, Linda Vahdat, Valerie M. Weaver, Marcus B. Smolka, Paul N. Span, Jan Lammerding
Publikováno v:
Oncogene, 41, 4211-4230
Oncogene, 41, 36, pp. 4211-4230
Oncogene
Oncogene, 41, 36, pp. 4211-4230
Oncogene
Contains fulltext : 283431.pdf (Publisher’s version ) (Closed access) Aberrations in nuclear size and shape are commonly used to identify cancerous tissue. However, it remains unclear whether the disturbed nuclear structure directly contributes to
Autor:
Wanning Zhang, Ziguang Liu, Yanqing Ding, Xin Peng, Zhicheng Zeng, Yizhi Zhan, Li Liang, Feifei Wang, Shaowan Xu
Publikováno v:
Oncogene. 41:3719-3731
Background Metabolic reprogramming has been shown to be involved in cancer-induced PMN formation, but the underlying mechanisms have been insufficiently explored. Methods HAO1 expression in lung tissues and alveolar epithelial cells were deteted by q
Publikováno v:
Differentiation. 125:35-44
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal lung disease that is characterized by enhanced changes in stem cell differentiation and fibroblast proliferation. Lung resident mesenchymal stem cells (LR-MSCs) are im
Autor:
Samuel Long, Brian Berkemeier
Publikováno v:
Methods. 201:49-64
Sensitive detection of viral nucleic acids is critically important for diagnosis and monitoring of the progression of infectious diseases such as those caused by SARS-CoV2, HIV-1, and other viruses. In HIV-1 infection cases, assessing the efficacy of
Publikováno v:
The Journal of Gene Medicine. 25
Background Osteoarthritis (OA) represents a significant disabling condition that has been well documented as a significant health burden. Lymphocyte-specific kinase (LCK) has been reported to exhibit differential expression in OA. However, the specif
Publikováno v:
The Journal of Gene Medicine. 25
Background Glucocorticoid Modulatory Element-Binding protein 1 (GMEB1) suppresses caspase-mediated cell apoptosis. microRNA-320 (miR-320a) can inhibit tumor development by arresting tumor cell invasion. To our best knowledge, no previous study focuse