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Publikováno v:
Biochemical and Biophysical Research Communications. 573:19-26
As a common treatment of human glioma, ionizing radiation (IR) was reported to result in cell cycle arrest. However, the mechanisms underlying IR-induced abnormal cell cycle remain largely unclear. Here we found that IR caused an elevated expression
Autor:
Shinobu Yamaguchi, Junko Tachi, Woo Kim, Rie Matsushima-Nishiwaki, Haruhiko Tokuda, Hiroki Iida, Takashi Onuma, Kumiko Tanabe, Tomoyuki Hioki, Osamu Kozawa
Publikováno v:
Biochemistry and Cell Biology. 99:578-586
Duloxetine, a selective serotonin-norepinephrine reuptake inhibitor, is currently recommended for the treatment of chronic painful disorders such as fibromyalgia, chronic musculoskeletal pain, and diabetic peripheral neuropathy. We previously demonst
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-8 (2021)
Journal of Hematology and Oncology
Journal of Hematology and Oncology, BioMed Central, 2021, 14 (1), ⟨10.1186/s13045-021-01172-5⟩
Journal of Hematology and Oncology, 2021, 14 (1), ⟨10.1186/s13045-021-01172-5⟩
Journal of Hematology & Oncology
Journal of Hematology and Oncology
Journal of Hematology and Oncology, BioMed Central, 2021, 14 (1), ⟨10.1186/s13045-021-01172-5⟩
Journal of Hematology and Oncology, 2021, 14 (1), ⟨10.1186/s13045-021-01172-5⟩
Journal of Hematology & Oncology
Background New targeted antibody–drug conjugates (ADCs) against multiple myeloma are known to induce adverse effects that may lead to treatment discontinuation. Preclinical studies reported early severe ocular damage related to the use of belantama
Autor:
Noriko Mochizuki-Oda, Kazumasa Minami, Shigeru Miyagawa, Emiko Ito, Yoshiki Sawa, Maki Takeda, Akima Harada
Publikováno v:
Biochemical and Biophysical Research Communications. 574:91-96
A major concern in the clinical application of induced pluripotent stem cells (iPSCs) is the prevention of tumorigenesis after implantation. Stem cells with high proliferative and differentiation potential are sensitive to radiation. Therefore, we hy
Autor:
Yu-Lung Lau, Alan Kwok Shing Chiang, Daniel Ka Leung Cheuk, Alex Wing Kwan Leung, Wing Leung, Marco Ho, Shau Yin Ha, Ian C. K. Wong, Janette Kwok, Godfrey Chi-Fung Chan, P Ip, Wai Keung Chu, Jaime S. Rosa Duque, Chun Wing Luk, Alvin Siu-Cheung Ling, Wilfred Hing Sang Wong, Y.S. Chan, Gilbert T. Chua, Chi Kong Li, Anthony P.Y. Liu, Pamela P. W. Lee, Mike Yat Wah Kwan, Oscar Kuen Fong Yiu
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-4 (2021)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
Asparaginase is an important drug to treat childhood haematological malignancies. Data on the association between human leukocyte antigens (HLA) and asparaginase hypersensitivity among Chinese are lacking. We conducted a retrospective study to identi
Autor:
Christopher A. Girkin, Rafael Grytz, Seyed Mohammadali Rahmati, Alireza Karimi, J. Crawford Downs
Publikováno v:
Acta Biomater
Glaucoma is among the leading causes of blindness worldwide that is characterized by irreversible damage to the retinal ganglion cell axons in the lamina cribrosa (LC) region of the optic nerve head (ONH), most often associated with elevated intraocu
Autor:
Kenji Oritani, Ryuta Muromoto, Nao Koizumi, Kota Kagohashi, Tadashi Matsuda, Yuichi Kitai, Shoya Kawahara, Yukie Yamauchi, Fuki Kobayashi, Yuto Sasaki, Kodai Saitoh, Jun-ichi Kashiwakura
Publikováno v:
Biochemical and biophysical research communications. 572:80-85
Signal-transducing adaptor protein (STAP)-2 is one of the STAP family adaptor proteins and ubiquitously expressed in a variety types of cells. Although STAP-2 is required for modification of Fc epsilon RI signal transduction in mast cells, other invo
Autor:
Zhijie Zhang, Jiaxing Liu, Liang Huang, Anqi Ren, Xiqin Tong, You Qin, Yingqi Leng, Zhu Haichuan, Zhang Zijian, Tong-Cun Zhang, Zhe Li, Shangkun Zhang, Han Wu, Hong Cen, Xiyu Liu, Kunyu Yang, Jinjue Liang, Shi Jiangzhou, Fuling Zhou
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-5 (2021)
Journal of Hematology & Oncology
Journal of Hematology & Oncology
CAR T cell therapy has shown dramatic clinical success in relapsed or refractory (r/r) B-ALL and other haematological malignancies. However, the loss of specific antigens, cell fratricide, T cell aplasia, and normal T cell separation are challenges i
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Background. Acute myocardial infarction (AMI) is a common cardiovascular disease with high disability and mortality. Circular RNAs (circRNAs) are implicated in the pathomechanism of multiple human diseases, including AMI. This study intended to explo
Autor:
Jae Wook Jeong, Kyong Hye Joung, Hyun-Jin Kim, Sorim Choung, Seon Mee Kang, Ji Min Kim, Bon Jeong Ku
Publikováno v:
Biochemical and Biophysical Research Communications. 572:92-97
Brown adipose tissue (BAT) is an anti-obese and anti-diabetic tissue that stimulates energy expenditure in the form of adaptive thermogenesis through uncoupling protein 1 (UCP1). Mitogen-inducible gene-6 (Mig-6) is a negative regulator of epidermal g