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Autor:
Young Chan Kim, Hye Ryun Kang, Jeonghyeon Kim, Boram Bae, Ruth Lee Kim, Eui-Man Jeong, Subin Kim, Sang Heon Cho
Publikováno v:
Experimental Lung Research. 47:465-475
Transforming growth factor beta 1 (TGF-β1) induces pulmonary fibrosis by enhancing epithelial apoptosis and affects the enzymatic activity of transglutaminase 2 (TG2). The aim of this study was to determine the role of TG2 in TGF-β1-induced lung re
Autor:
Masaki Hanibuchi, Toshifumi Tezuka, Hisanori Uehara, Yoshinori Aono, Masahiko Azuma, Mayo Kondo, Hirohisa Ogawa, Yasuhiko Nishioka
Publikováno v:
Experimental Lung Research. 47:451-463
Purpose: IL-33 is known to induce corticosteroid-resistant eosinophilic inflammation and airway remodeling by activating type 2 innate lymphoid cells (ILC2s). Although the RAS signal pathway plays an important role in IL-33-induced ILC2s activation a
Autor:
I Sogut, C S Elgormus, S G Gur, Bahattin Özkul, Yiğit Uyanıkgil, D Erisik Tanriover, Ibrahim Halil Sever, Oytun Erbaş, Emel Öykü Çetin, O Ozkul
Publikováno v:
Experimental Lung Research. 47:426-435
Purpose: Although several studies demonstrate the anti-inflammatory effect of oxytocin in different pathophysiological processes, there are limited data describing the impact of oxytocin on acute respiratory distress syndrome (ARDS). We aimed to eluc
Publikováno v:
Immunopharmacology and Immunotoxicology. 43:778-789
BACKGROUND Non-alcoholic steatohepatitis (NASH) is an extreme form of non-alcoholic fatty liver disease. The present study concentrated on the role of Capillin, a polyacetylene compound isolated from Artemisia capillaris Thunb., in NASH development.
Publikováno v:
Autoimmunity. 54:483-492
Infantile pneumonia is a common inflammatory disease with the infections of various pathogens in lower respiratory tracts. Here, the role and working mechanism of circular RNA (circRNA) ubiquinol-cytochrome c reductase core protein 2 (circ-UQCRC2; hs
Autor:
Yanhua Hou, Min Lai, Zhaojing Zhu, Xiaojing Zhang, Chunlei Zhang, Ke Shen, Qiang Tang, Xingtang Fang
Publikováno v:
Journal of Biomaterials Science, Polymer Edition. 32:1865-1881
Osteoporosis is the most common cause of fractures in middle-aged and elderly people. Fracture repair can be difficult due to the decreased bone volume in osteoporosis patients and implants are often required. In this study, a slow-release system for
Publikováno v:
Cancer Investigation. 39:721-733
This study evaluated the inhibitory effects of bilirubin on colony formation and cell migration of melanoma and non-melanoma skin cancer cell lines SK-MEL-3 and A431, compared with normal human dermal fibroblasts (HDF). The IC50 obtained from the MTT
Autor:
Yuan Wang, Chen Cheng, Jing-Chao Su, Yi Zhang, Xin-Fang Zhang, Zi-Bing Liu, Yong-Kang Sun, Yi-Nan Zhu, Shui-Ying Xiang, Yu-Meng Ye
Publikováno v:
Experimental Lung Research. 47:301-310
OBJECTIVE Chronic obstructive pulmonary disease (COPD) is a respiratory disease with high morbidity and mortality worldwide, so far there is no ideal treatment method. Previous studies have shown that hydrogen (H2) is involved in the treatment of COP
Autor:
Hossein Aghamollaei, Mohaddese Haddadi, Farshad Yazdani, Alireza Shahriary, Melad Sabzevare, Ali Karami
Publikováno v:
Immunopharmacology and Immunotoxicology. 43:452-460
Cornea injury of sulfur mustard (SM) is considered as the most devastating injuries to the eye. This study aimed to evaluate the single and combined effects of N-acetyl cysteine (NAC) and doxycycli...
Autor:
A. Rosinskiy, E. Vdovina, S. N. Bach, Valentin P. Volobaev, Alexey V. Larionov, E. Shchetnikova
Publikováno v:
Toxicology Mechanisms and Methods. 31:531-537
Single-cell gel electrophoresis (comet assay) is a valuable test that can be used in ecotoxicological, epidemiological, and biomonitoring contexts. We assessed the effects of short- (without cryopr...