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Autor:
Thita Chiasakul, Jeffrey I. Zwicker
Publikováno v:
Thromb Res
Venous thromboembolism (VTE) is a common complication in patients with cancer. Warfarin has largely been replaced by low-molecular-weight heparin (LMWHs) and direct oral anticoagulants (DOACs) as the standard of care in cancer-associated VTE. The sur
Autor:
Sandrine Accassat, Isabelle Mahé, Laurent Bertoletti, Hélène Helfer, Lucile Cognet, Marie Giraud, Céline Chapelle, Patrick Mismetti, Judith Catella, Silvy Laporte
Publikováno v:
Thrombosis Research. 208:156-161
Background Concomitant anticoagulant and antiplatelet therapy increases bleeding risk, but most data are derived from patients with atrial fibrillation. Patients with venous thromboembolism (VTE) may differ. Objective To study the management of patie
Autor:
Mimi Lo, Frank Oley, Richard Fong, Tiffany K. Pon, Mary McGann, Ila M Saunders, Angela Lee, Anjlee Mahajan, Shanna Block
Publikováno v:
Thrombosis Research. 208:148-155
Introduction Patients with central nervous system malignancies have limited representation in studies evaluating DOACs for VTE treatment. This study evaluated the safety and efficacy of DOACs in comparison with LMWH for cancer-associated VTE in patie
Publikováno v:
Thrombosis Research. 208:18-25
Introduction Continuous intravenous unfractionated heparin (UFH) is a mainstay of therapeutic anticoagulation in the acute setting. The two most common laboratory tests for monitoring UFH are the activated partial thromboplastin time (aPTT) and antif
Autor:
Marc Carrier, Philip S. Wells, Lana A Castellucci, Aurélien Delluc, Ameeta L. Nayak, Amin Zahrai, Tzu-Fei Wang, Ranjeeta Mallick
Publikováno v:
Thrombosis Research. 208:79-82
Background Apixaban has been shown to significantly decrease the rate of VTE among intermediate-to-high risk patients starting chemotherapy compared to placebo. This investigation sought to determine the impact of apixaban among different subgroups o
Autor:
Justine Brodard, Anne Angelillo-Scherrer, Andrea De Gottardi, Sara Calzavarini, Annalisa Berzigotti, Claudia Quarroz
Publikováno v:
Brodard, Justine; Calzavarini, Sara; Quarroz, Claudia; Berzigotti, Annalisa; De Gottardi, Andrea; Angelillo-Scherrer, Anne (2021). Resistance to thrombomodulin correlates with liver stiffness in chronic liver disease a prospective single-center cohort study. Thrombosis research, 207, pp. 40-49. Elsevier 10.1016/j.thromres.2021.09.007
INTRODUCTION Chronic liver disease (CLD) is characterized by changes in haemostasis, embracing both hypo- and hypercoagulability. Global hemostatic tests such as thrombin generation assays evaluate the hemostatic balance, to better assess bleeding an
Publikováno v:
Thrombosis Research, 207, 143-149. Elsevier Science
Introduction Hormonal contraception is a well-known risk factor for venous thromboembolism (VTE). APC resistance and impaired functions of protein S and TFPI are thought to play an important role in the pathogenesis of hormone-related VTE. It is unkn
Autor:
Mark Crowther, Catherine Anne Lovatt
Publikováno v:
Thrombosis Research. 207:58-61
Heparin-induced thrombocytopenia in pregnancy is an uncommon phenomenon which rarely occurs in the first trimester. Therapeutic options and duration of therapeutic anticoagulation are varied amongst reported published cases. We report a 41-year-old f
Autor:
Musa Sesay, Laurent Weinmann, Céline Delassasseigne, Thibaud Cavaillez, Christine Mouton, Stéphanie Roullet, Matthieu Biais, Chloé James
Publikováno v:
Thrombosis Research
Thrombosis Research, Elsevier, 2021, 206, pp.76-83. ⟨10.1016/j.thromres.2021.08.010⟩
Thrombosis Research, Elsevier, 2021, 206, pp.76-83. ⟨10.1016/j.thromres.2021.08.010⟩
Introduction The use of direct oral anticoagulants (DOAC) is increasing. Specific concentrations are available and have been proven to be reliable and reproducible in optimising patient care. This retrospective, monocentric study aimed to describe th
Autor:
Marguerite Neerman-Arbez, Timea Szanto, Alessandro Casini, Elina Lehtinen, Nathalie Trillot, Antoine Rauch, Maxime Arbez, Raquel Bártolo, Rui Vilar
Publikováno v:
Thrombosis Research, Vol. 206 (2021) pp. 5-8
This study describes the identification of two new mutations of the fibrinogen beta-chain in patients with inherited fibrinogen deficiency. Modelling of the impact of the mutations predict that these single amino acid substitutions are sufficient to