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Publikováno v:
Thrombosis Research. 202:24-30
Introduction Following successful phase-III trials, direct oral anticoagulants such as rivaroxaban have largely replaced warfarin for stroke prevention in atrial fibrillation (SPAF). However, data from randomized trials should be confirmed in unselec
Autor:
Hugo ten Cate, Moniek P.M. de Maat, Diederik W.J. Dippel, Samantha J. Donkel, Frank W.G. Leebeek, Karmen Pater
Publikováno v:
Thrombosis Research, 202, 139-144. Elsevier Ltd.
Thrombosis Research, 202, 139-144. Elsevier Science
Thrombosis Research, 202, 139-144. Elsevier Science
Introduction Understanding the underlying mechanisms in ischemic stroke (IS) in young adults remains challenging. Thrombin activates processes that contribute to the development and progression of arterial diseases. We investigated the association be
Autor:
James Gordon Payne, Martha L Louzada, Michael J. Kovacs, Dou-Anne Siew, Eri Kawata, Alejandro Lazo-Langner
Publikováno v:
Thrombosis Research. 202:90-95
Background Clinical manifestations and optimal management strategies in patients with splanchnic vein thrombosis (SVT) are not well characterized. Methods We conducted a retrospective cohort study including all newly diagnosed SVT evaluated between J
Autor:
Alexandre Soares Ferreira Júnior, Oluwatoyosi A. Onwuemene, Maragatha Kuchibhatla, Stephen H. Boyle
Publikováno v:
Thrombosis Research. 201:6-14
Introduction In heparin-induced thrombocytopenia (HIT), selected patients are treated with therapies directed at the immune response, intravenous immunoglobulin (IVIG) and therapeutic plasma exchange (TPE). To determine IVIG and TPE characteristics a
Autor:
Yvonne M. C. Henskens, Jan-Willem E M Sels, Bas C. T. van Bussel, Magdolna Nagy, Tom Van De Berg, Rene van Oerle, Henri M. H. Spronk, Hugo ten Cate, Anne-Marije Hulshof
Publikováno v:
Thrombosis Research, 201, 84-89. Elsevier Science
Thrombosis Research
Thrombosis Research
INTRODUCTION: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection is associated with a clear prothrombotic phenotype. Although the exact pathophysiological mechanisms are not yet fully understood, thrombosis is clearly a highly impo
Autor:
Keisuke Tsuda, Yasuo Terayama, Kiyotaka Oi, Shinsuke Narumi, Tetsuya Maeda, Asami Kamada, Kazumasa Oura, Yoko Ishigaku, Mie Shimizu, Tatsunori Natori, Makiko Yoshida
Publikováno v:
Thrombosis Research. 201:123-130
Introduction Dabigatran, a direct thrombin inhibitor, has been widely used in patients with non-valvular atrial fibrillation (NVAF) and is considered to have an antiplatelet effect. However, the mechanisms remain unclear. We evaluated protease-activa
Publikováno v:
Thrombosis Research. 208:230-232
Autor:
Tanvi Patil, Jesse Hobson
Publikováno v:
Thrombosis Research. 200:56-63
Oral anticoagulants (OAC) have shown to affect bone mineral density and cause osteoporosis. Limited studies have investigated the relationship between its use and risk of osteoporosis. We aim to compare the risk of osteoporosis in patients on warfari
Autor:
Peter Busch-Østergren, Shivam Patel, Samuel Jaimian Church, Thomas W. Wakefield, Mackenzie Adams, James Henderson, Benjamin E. Tourdot, Adriana Yamaguchi, Tadas Kasputis, Ajjai Alva, Michael Holinstat, Aaron M. Udager, Zachery R. Reichert, Xiu Cao, Ganesh S. Palapattu, Alexander Zaslavsky, Samantha K. Lee, Sydney Ohl, Todd M. Morgan, Sethuramasundaram Pitchiaya
Publikováno v:
Thromb Res
INTRODUCTION: Despite the great promise for therapies using antisense oligonucleotides (ASOs), their adverse effects, which include pro-inflammatory effects and thrombocytopenia, have limited their use. Previously, these effects have been linked to t
Publikováno v:
Voukalis, C, Lip, G Y H & Shantsila, E 2021, ' Effects of antithrombotic drugs on the prothrombotic state in patients with atrial fibrillation : The west Birmingham atrial fibrillation project ', Thrombosis Research, vol. 200, pp. 149-155 . https://doi.org/10.1016/j.thromres.2021.02.005
THROMBOSIS RESEARCH
THROMBOSIS RESEARCH
Background: Direct oral anticoagulants (DOACs) are known to prevent thrombosis but there is limited information about their activity on the clot formation and lysis cascade. Objectives: This study assesses the role of apixaban, one of the four licenc