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Autor:
Rene van Oerle, Natalie J Jooss, Linda Herfs, Yvonne M. C. Henskens, Johan W. M. Heemskerk, Mike Kozlowski, Patric Machiels, Floor C J I Heubel-Moenen, Frauke Swieringa
Publikováno v:
Thrombosis Research, 203, 46-56. Elsevier Science
Thrombosis Research
Thrombosis Research
Introduction: Current developments to assess qualitative and quantitative platelet traits in flowed whole-blood are based on microfluidic devices that mostly operate at room temperature. However, operation at physiological temperature (37 degrees;C)
Autor:
Keisuke Tsuda, Yasuo Terayama, Kiyotaka Oi, Shinsuke Narumi, Tetsuya Maeda, Asami Kamada, Kazumasa Oura, Yoko Ishigaku, Mie Shimizu, Tatsunori Natori, Makiko Yoshida
Publikováno v:
Thrombosis Research. 201:123-130
Introduction Dabigatran, a direct thrombin inhibitor, has been widely used in patients with non-valvular atrial fibrillation (NVAF) and is considered to have an antiplatelet effect. However, the mechanisms remain unclear. We evaluated protease-activa
Autor:
Peter Busch-Østergren, Shivam Patel, Samuel Jaimian Church, Thomas W. Wakefield, Mackenzie Adams, James Henderson, Benjamin E. Tourdot, Adriana Yamaguchi, Tadas Kasputis, Ajjai Alva, Michael Holinstat, Aaron M. Udager, Zachery R. Reichert, Xiu Cao, Ganesh S. Palapattu, Alexander Zaslavsky, Samantha K. Lee, Sydney Ohl, Todd M. Morgan, Sethuramasundaram Pitchiaya
Publikováno v:
Thromb Res
INTRODUCTION: Despite the great promise for therapies using antisense oligonucleotides (ASOs), their adverse effects, which include pro-inflammatory effects and thrombocytopenia, have limited their use. Previously, these effects have been linked to t
Publikováno v:
Thrombosis Research. 196:510-515
Introduction On-treatment platelet aggregability represents the major form of functional assessment for patients treated with P2Y12 receptor antagonists, with “high” on-treatment platelet aggregability (HTPA) predicting thrombotic risk. However H
Publikováno v:
Thrombosis Research. 196:175-185
AMP-activated protein kinase (AMPK) is a metabolic master switch that has critical role in wide range of pathologies including cardiovascular disorders. As AMPK-α2 knockout mice exhibit impaired thrombus stability, we asked whether pharmacological i
Autor:
Ido Weinberg, Giovanni Barillari, Justo Ruiz-Ruiz, Manuel Alejandro Lorente, Javier Trujillo-Santos, Riete Investigators, Ramón Lecumberri, Peter Verhamme, Manuel Monreal, Benjamin Brenner, Pedro Ruiz-Artacho, Fernando J. Vazquez
Publikováno v:
Thrombosis Research. 195:139-145
Introduction Treatment of venous thromboembolism (VTE) in cancer patients with thrombocytopenia is challenging due to perceived higher risk of bleeding. Material and methods We used the RIETE registry to compare the 10- and 30-day outcomes in cancer
Publikováno v:
Thrombosis Research. 193:15-21
Introduction Systemic hypercoagulation is often a severe complication of infective and inflammatory diseases, which overcome the hemostatic balance and lead to multiple thrombotic occlusions in the microvasculature and organ damage and is related to
Autor:
Lori-Ann Linkins, Kerstin de Wit
Publikováno v:
Thrombosis Research. 198:83-85
We present a case of acute pulmonary embolism in a patient with myelofibrosis and thrombocytopenia. The patient had a history of portal vein thrombosis and had taken warfarin for the past six years. At the time of his pulmonary embolism diagnosis, hi
Publikováno v:
Thrombosis Research. 187:186-196
Under normal conditions, the hemostatic system, that includes the involvement of the coagulation response and platelets, is anatomically and functionally inseparable from the vasculature. However, the hemostatic response always occurs in a wide range
Autor:
Jun Liu, Liuan Qin, Yangxun Wu, Jia Liu, Li Peng, Yuting Zou, Tong Yin, Rina Du, Ziqian Wang, Xuyun Wang
Publikováno v:
Thrombosis Research. 186:71-74