Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Smith, David A."'
Autor:
Karen L Locker, Smith David W, Timothy Harrison, Christopher John Swain, Nadia M.J. Rupniak, Michael J Cumberbatch, Rachel K. Conley, Karen A. Maubach, Louise Hewson, David J. Williamson, Michael Rigby, G Mason, Ruth O'Donnell
Publikováno v:
The Journal of Neuroscience. 22:7730-7736
Substance P receptor [neurokinin 1 (NK(1))] antagonists (SPAs) represent a novel mechanistic approach to antidepressant therapy with comparable clinical efficacy to selective serotonin reuptake inhibitors (SSRIs). Because SSRIs are thought to exert t
Autor:
Thomas W. Rosahl, Robin A. Morton, Frederick M. Kuenzi, Stephen M. Fitzjohn, Graham L. Collingridge, Ceri H. Davies, Huw D. Lewis, Guy R. Seabrook, Smith David W, Mark S. Shearman, David S. Reynolds
Publikováno v:
The Journal of Neuroscience. 21:4691-4698
We have studied synaptic function in a transgenic mouse strain relevant to Alzheimer's disease (AD), overexpressing the 695 amino acid isoform of human amyloid precursor protein with K670N and M671L mutations (APP695SWE mice), which is associated wit
Autor:
Sally A. Thompson, Louise Hewson, Ruth O'Donnell, Dalip J. S. Sirinathsinghji, George McAllister, Keith A. Wafford, Demetrios K. Vassilatis, Michael Rigby, Paul J. Whiting, Robert P. Heavens, George R. Marshall, Smith David W, Timothy P. Bonnert
Publikováno v:
The Journal of Neuroscience. 17:5027-5037
We report the isolation and characterization of a cDNA encoding a novel member of the GABA receptor gene family, ε. This polypeptide is 506 amino acids in length and exhibits its greatest amino acid sequence identity with the GABAAreceptor γ3 subun