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Autor:
Jacques U. Baenziger, Jeremy J. Keusch, Stephen M. Manzella, Kwame Nyame, Richard D. Cummings
Publikováno v:
The Journal of biological chemistry. 275(33)
The large array of different glycolipids described in mammalian tissues is a reflection, in part, of diverse glycosyltransferase expression. Herein, we describe the cloning of a UDP-galactose: beta-d-galactosyl-1,4-glucosylceramide alpha-1, 3-galacto
Autor:
S E, Devine, P W, Melera
Publikováno v:
The Journal of biological chemistry. 269(8)
Mammalian cells displaying the multidrug resistance (mdr) phenotype are refractory to the toxic effects of a group of unrelated natural product drugs, many of which are used for cancer chemotherapy. The pattern of cross-resistance can be extremely va
Publikováno v:
The Journal of biological chemistry. 260(1)
We present and evaluate a model for the secondary structure and membrane orientation of 3-hydroxy-3-methylglutaryl coenzyme A reductase, the glycoprotein of the endoplasmic reticulum that controls the rate of cholesterol biosynthesis. This model is d