Zobrazeno 1 - 10
of 155
pro vyhledávání: ''
Publikováno v:
The American Journal of Medicine. 131:134-140
Lifestyle modification is the cornerstone of preventing atherosclerotic cardiovascular disease. When this is not sufficient in reducing risk, statin therapy is first line. Heart Outcomes Prevention Evaluation (HOPE-3) was a randomized controlled tria
Publikováno v:
The American Journal of Medicine. 132:1295-1304.e3
Background The role of aspirin for primary prevention of cardiovascular diseases remains controversial, particularly in the context of contemporary aggressive preventive strategies. Methods Relevant randomized clinical trials were included, and risk
Autor:
Savitha Subramanian, Janet B. McGill
Publikováno v:
The American Journal of Medicine. 132:S49-S57.e5
Sodium-glucose co-transporter 2 (SGLT2) inhibitors have a well-defined safety profile based on data obtained from numerous clinical trials, including cardiovascular outcomes trials (CVOTs) and postmarketing pharmacovigilance reporting. Adverse events
Autor:
Melissa Loeks, Cathy Y. Lu, Nathan E. Wineinger, Thomas J. McCarthy, Stuti J. Jaiswal, Janet Song, Solana Garcia, Christoffel J. van Niekerk, Dae Y. Kang, Robert L. Owens
Publikováno v:
The American Journal of Medicine. 131:1110-1117.e4
Purpose Studies suggest that melatonin may prevent delirium, a condition of acute brain dysfunction occurring in 20%-30% of hospitalized older adults that is associated with increased morbidity and mortality. We examined the effect of melatonin on de
Autor:
Gholamhosein R. Omrani, Mohammadreza Kalantarhormozi, Kamyar Asadipooya, Iraj Nabipour, Mohammad Reza Ravanbod
Publikováno v:
The American Journal of Medicine. 126:420-424
Objective Subclinical hypothyroidism is a health state that is associated with hypercholesterolemia, infertility, iron-deficiency anemia, and poor obstetric outcome. This article summarizes the results of a prospective clinical investigation of wheth
Autor:
Peter Sheehan, Cyrus V. Desouza, Douglas S. Denham, Lawrence A. Lavery, Tina K. Thethi, Julio Rosenstock, Teodoro Bottiglieri, Yahya Daoud, Vivian Fonseca, Fernando Ovalle
Publikováno v:
The American Journal of Medicine. 126:141-149
Purpose To determine whether a combination of L-methylfolate, methylcobalamin, and pyridoxal-5′-phosphate (LMF-MC-PLP [Metanx; Pamlab LLC, Covington, La]) improves sensory neuropathy. Research Design and Methods This multicenter, randomized, double
Autor:
Claudio Cirenza, Felipe Martini, Adauto Castelo Filho, João Batista Petracco, João Carlos Vieira da Costa Guaragna, Luiz Carlos Bodanese, Angelo Amato Vicenzo de Paola, Stevie Jorge Horbach, Renato D. Lopes, Rajendra H. Mehta, Nafarm Investigators
Publikováno v:
Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
PURPOSE: We sought to assess the effect of naproxen versus placebo on prevention of atrial fibrillation after coronary artery bypass graft (CABG) surgery.METHODS: in this randomized, double-blind, placebo-controlled, single-center trial of 161 consec
Autor:
Simon Heller, Christopher P. Cannon, Richard M. Bergenstal, William B. White, Kamlesh Khunti, Heena Howitt
Publikováno v:
The American Journal of Medicine. 131:813-819.e5
We evaluated the antihyperglycemic efficacy and safety of adding the dipeptidyl dipeptidase-4 inhibitor alogliptin to metformin and sulphonylurea in the treatment of type 2 diabetes in the Examination of Cardiovascular Outcomes with Alogliptin versus
Publikováno v:
The American Journal of Medicine. 122:290-300
Objective To quantify the incremental effect of combining blood pressure-lowering drugs from any 2 classes of thiazides, beta-blockers, angiotensin-converting enzyme inhibitors, and calcium channel blockers over 1 drug alone and to compare the effect
Autor:
Susan H. Swartz, Daniel E. Singer, Richard C. Pasternak, Nancy A. Rigotti, Nancy Torres-Finnerty, Karen M. Emmons, Kathleen M. McKool, Yuchiao Chang, Anne N. Thorndike, Susan Regan
Publikováno v:
The American Journal of Medicine. 119:1080-1087
Purpose Smoking cessation after myocardial infarction reduces cardiovascular mortality, but many smokers cannot quit despite state-of-the-art counseling intervention. Bupropion is effective for smoking cessation, but its safety and efficacy in hospit