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Publikováno v:
The American Journal of Medicine. 134:1465-1475
Bariatric surgery has emerged as a therapy for obesity and the associated comorbidities. Obesity has been shown to be a risk factor for atrial fibrillation as well as venous thromboembolism, both of which are conditions that warrant anticoagulation.
Publikováno v:
The American Journal of Medicine. 134:1330-1338
Overt hepatic encephalopathy is a generally reversible neurologic complication of cirrhosis. Overt hepatic encephalopathy has been associated with poor hospitalization- and mortality-related outcomes, which is important given increasing hepatic encep
Autor:
Gregor Lindner, Svenja Ravioli, Shawki Bahmad, Aristomenis K. Exadaktylos, Christoph Schwarz, Georg-Christian Funk
Publikováno v:
The American Journal of Medicine. 134:1148-1154
Background: Thiazide diuretics are a mainstay in the management of hypertension and often associated with dyselectrolytemias. We investigated the prevalence of and risk factors for hyponatremia and hypokalemia in thiazide users, substance-specific di
Publikováno v:
The American Journal of Medicine. 134:926-929
Background Intrathoracic involvement with lymphomas is common and manifests lymphadenopathy as well as a wide spectrum of imaging abnormalities in the lungs. Intravascular large B-cell lymphoma (IVLBCL) is a rare extranodal subtype of large B-cell ly
Autor:
Pradyumna Agasthi, Nirat Beohar, David R. Holmes, Mohamed Allam, Pattara Rattanawong, Sai Harika Pujari, Komandoor Srivathsan, Dan Sorajja, Win Kuang Shen, William K. Freeman, Ramila A. Mehta, Hicham El Masry, Farouk Mookadam, Eric H. Yang, Hasan Ashraf, Xiaoxi Yao, Anusha Shanbhag, Reza Arsanjani, Siva K. Mulpuru, Peter A. Noseworthy
Publikováno v:
The American Journal of Medicine. 134:788-796
Background Although direct oral anticoagulants (DOACs) have been shown to be effective at reducing the risk of stroke in patients with atrial fibrillation/flutter (AF), they are sometimes underdosed off-label to mitigate their associated higher bleed
Publikováno v:
The American Journal of Medicine. 134:477-481
Autor:
Charity J. Morgan, Hans Moore, Markus S. Anker, Cherinne Arundel, Prakash Deedwania, Richard M. Allman, Samuel Wopperer, Steven N. Singh, Charles Faselis, Gregg C. Fonarow, Qing Zeng, Phillip H. Lam, Lakshmi Tummala, Pamela Karasik, Ali Ahmed
Publikováno v:
The American Journal of Medicine. 133:1460-1470
Background Digoxin reduces the risk of heart failure hospitalization but has no effect on mortality in patients with heart failure without atrial fibrillation in the randomized controlled trial setting. Observational studies of digoxin use in patient
Publikováno v:
The American Journal of Medicine. 133:1209-1218
Background Chronic opioid use and dependence is common in patients with chronic pancreatitis. Patients with acute pancreatitis are frequently treated with opioids, but their risk for ongoing use is not well known. The aim of our study is to character
Autor:
Cherinne Arundel, Milton Packer, Steven N. Singh, Yan Cheng, Wayne C. Levy, Richard M. Allman, Vijaywant Brar, Wen-Chih Wu, Gregg C. Fonarow, Phillip H. Lam, Michael R. Zile, Ali Ahmed, Gauravpal S. Gill
Publikováno v:
The American Journal of Medicine. 133:1187-1194
Background Digoxin reduces the risk of heart failure hospitalization in patients with heart failure with reduced ejection fraction. Less is known about this association in patients with heart failure with preserved ejection fraction (HFpEF), the exam
Autor:
Jack Mardekian, W. Schuyler Jones, Renato D. Lopes, Keith Friend, Xianying Pan, Allison Keshishian, Xuemei Luo, Jan Steffel, Xiaoyan Li, Kiran Gupta, Cristina Masseria, Onur Baser, Melissa Hamilton, Manuela Di Fusco
Publikováno v:
The American Journal of Medicine. 133:1229-1238
Results There were 33,269 apixaban-warfarin, 9,345 dabigatran-warfarin, and 42,156 rivaroxaban-warfarin matched pairs, with a median follow-up of 4-5 months. Compared with warfarin, apixaban was associated with lower rates of stroke/systemic embolism