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Autor:
Gregory S. Park, James S. Hodges, Paul Bangirana, Estela Shabani, Thomas Lavstsen, Weihua Guan, Gregory M. Vercellotti, Chandy C. John, Robert O. Opoka
Publikováno v:
Scientific Reports
Shabani, E, Opoka, R O, Bangirana, P, Park, G S, Vercellotti, G M, Guan, W, Hodges, J S, Lavstsen, T & John, C C 2016, ' The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria ', Scientific Reports, vol. 6, 27084 . https://doi.org/10.1038/srep27084
Shabani, E, Opoka, R O, Bangirana, P, Park, G S, Vercellotti, G M, Guan, W, Hodges, J S, Lavstsen, T & John, C C 2016, ' The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria ', Scientific Reports, vol. 6, 27084 . https://doi.org/10.1038/srep27084
The endothelial protein C receptor (EPCR) appears to play an important role in Plasmodium falciparum endothelial cell binding in severe malaria (SM). Despite consistent findings of elevated soluble EPCR (sEPCR) in other infectious diseases, field stu