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Autor:
John Patrick Aggleton, Emma Jane Kidd, Jilu P. Mole, John Evans, Claudia Metzler-Baddeley, Fabrizio Fasano, Rebecca Sims
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-25 (2020)
Scientific Reports
Scientific Reports
APOE-ε4 is a main genetic risk factor for developing late onset Alzheimer’s disease (LOAD) and is thought to interact adversely with other risk factors on the brain. However, evidence regarding the impact of APOE-ε4 on grey matter structure in as
Autor:
Jung-Lung Hsu, Tzu-Chen Yen, Ing-Tsung Hsiao, Nobuyuki Okamura, Yi-Hsin Weng, Kun-Ju Lin, Chin-Song Lu, Shih-Hsin Chen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
The associations of 18F-THK5351 tau positron emission tomography (PET) findings with core domains of progressive supranuclear palsy (PSP) and its diagnostic certainty have yet to be fully elucidated. The 18F-THK5351 PET patterns of 17 patients with P
Autor:
Sung-Min Park, Jinhwan Baik, Chang Wook Jeong, Eue Keun Choi, Won Hoon Song, Hae Young Lee, Hyeon Hoe Kim
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Catheter-based renal denervation (RDN) was introduced to treat resistant hypertension. However, the reduction in blood pressure after the RDN was modest. Catheter-based RDN was performed only at main renal arteries, except for accessory and branch ar
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Acute cerebral ischaemia may lead to serious consequences, including brain injury caused by uncontrolled reperfusion, which occurs when circulation is re-established. The long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) pla
Autor:
Radovan Borojevic, Aline Silva da Cruz, Tatiana Coelho-Sampaio, Barbara Gomes da Rosa, Catarina Freitas, Marcos Assis Nascimento, Martín Hernán Bonamino, Maria Isabel D. Rossi, Daiana Vieira Lopes Alves, Raphael de Siqueira Santos, Karla Menezes
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-21 (2020)
Scientific Reports
Scientific Reports
Angiogenesis is considered to mediate the beneficial effects of mesenchymal cell therapy in spinal cord injury. After a moderate balloon-compression injury in rats, injections of either human adipose tissue-derived stromal/stem cells (hADSCs) or thei
Autor:
Alka Bhatia, Amanjit Bal, Neeraj Khatri, Shivani Jaiswal, Nayudu Nallabelli, Vivek Singh Malik, Deep Maheshwari, Rajesh Kumar, Neenu Jacob, Naresh Sachdeva, Savita Verma
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Type-1 diabetes (T1D) is an autoimmune disease caused by progressive loss of insulin-producing beta cells in the pancreas. Butyrate is a commensal microbial-derived metabolite, implicated in intestinal homeostasis and immune regulation. Here, we inve
Autor:
Yan Huang, Zhong-Yuan Hu, Hui Yang, Hong-Mei Yu, Wan-Xia Xie, Li-Min Tian, Na Jiang, Ai-Ai Chu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Obstructive sleep apnea syndrome (OSAS) can lead to alterations in right ventricular (RV) performance and pulmonary vascular haemodynamics. Additionally, altitude-related hypoxia is associated with pulmonary vasoconstriction, and the effect of high-a
Autor:
Russell P. Bowler, Stephanie Jeong, Victor Kim, Fernando J. Martinez, Richard C. Boucher, Robert Paine, Mark T. Dransfield, MeiLan K. Han, Igor Barjaktarevic, J. Michael Wells, Stephen I. Rennard, Mehmet Kesimer, Wanda K. O'Neal, Jeffrey L. Curtis, Huaqing Zhao, Robert J. Kaner, Sarah L. O’Beirne, Christopher B. Cooper, Stephanie A. Christenson, Prescott G. Woodruff
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
COPD, chronic bronchitis (CB) and active smoking have all been associated with goblet cell hyperplasia (GCH) in small studies. Active smoking is strongly associated with CB, but there is a disconnect between CB clinical symptoms and pathology. Chroni
Autor:
Edyta Lukasik, Jakub Smołka, Grzegorz Zieliński, Aleksandra Bys, Maria Skublewska-Paszkowska, Piotr Gawda, Magdalena Zawadka
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The purpose of this study is to compare recreationally physically active females and males with regard to spine, pelvis and lower limb joints peak angles in each plane of motion during a single leg squat (SLS). The second aim is to investigate the re
Autor:
Soon Jun Hong, Cheol Woong Yu, Jae Hyoung Park, Jae Young Cho, Duck Hyun Jang, Jong-Ho Kim, Hyung Joon Joo, Sang A. Cho, Do Sun Lim, Hyungdon Kook
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1), neutrophil gelatinase-associated lipocalin (NGAL), and matrix metalloproteinase-9 (MMP-9) are inflammatory biomarkers involved in plaque destabilization resulting in acute coro