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Publikováno v:
RNA. 20:392-405
Adenosine-to-inosine (A-to-I) RNA editing is an endogenous regulatory mechanism involved in various biological processes. Site-specific, editing-state–dependent degradation of target RNA may be a powerful tool both for analyzing the mechanism of RN
Publikováno v:
RNA. 19:1309-1314
2-Selenouridine (SeU) is one of the naturally occurring modifications of Se-tRNAs (SeU-RNA) at the wobble position of the anticodon loop. Its role in the RNA-RNA interaction, especially during the mRNA decoding, is elusive. To assist the research exp
Autor:
Andres M. Patino, Julianne Caton-Williams, Zhen Huang, Jaya Punetha, Manindar Kaur, Lina Lin, Jia Sheng
Publikováno v:
RNA. 17:1932-1938
Phosphoroselenoate RNA (PSe-RNA) is nuclease resistant and has great potentials in X-ray crystal structure and function studies of noncoding RNAs and protein–RNA interactions. In order to conveniently synthesize PSe-RNA via transcription, we have d
Publikováno v:
RNA. 4:1186-1202
Domain 6 (D6) of group II introns contains a bulged adenosine that serves as the branch-site during self-splicing. In addition to this adenosine, other structural features in D6 are likely to contribute to the efficiency of branching. To understand t