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Autor:
Aleksander A. Mathé, Aram El Khoury, Erika Zambello, Laura Caberlotto, Patricia Jiménez-Vasquez
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 32(3)
Preclinical and clinical evidence suggests that neuropeptides play a role in the pathophysiology of mood disorders. In the present study, we investigated the involvement of the peptides corticotropin-releasing hormone (CRH), neuropeptide Y (NPY) and
Autor:
Patricia A. Broderick
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 26(7-8)
Detection of two biogenic amine neurotransmitters, serotonin (5-HT) and norepinephrine (NE) within the CA1 region of the hippocampus (HPC) of behaving male laboratory animals (Rattus norvegicus), was performed with miniature carbon sensors (BRODERICK
Autor:
Christoph Hiemke, Ulrich Schmitt
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 22(7)
1. 1. A test battery consisting of a standard open field, an enriched open field and an elevated plus maze was used to study behavior in rats. 2. 2. Male rats of the strains PVG/OlaHsd (PVG) and Sprague-Dawely-Hsd (SPRD) (150–200g body wt) were use
Autor:
Harvey J. Altman, Victoria L. Markovska, John S. Verbanac, Timothy J. Hill, Randall L. Commissaris
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 20(3)
1. 1. Female MR (“anxious”) and MNRA (“non-anxious”) Maudsley rats were tested in the CSD behavioral conflict paradigm (anxiety-like measure) and also in the FST paradigrn (depression-like measure). 2. 2. As expected, MNRA rats accepted signi
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 16(5)
1. The effects of chronic treatment with the atypical antipsychotic, clozapine, and classical antipsychotic, haloperidol, on serotonergic 5-HT-1c and dopamine D2 receptors in rat brain were studied with radioligand binding methods. 2. Two weeks' trea
Autor:
Helmut L. Haas, Susanne Birnstiel
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 16(5)
1. Recordings were obtained from transverse slices of rat hippocampus, which were placed in a perfusion chamber and superfused with oxygenated artificial cerebrospinal fluid. 2. The effects of 10 μM (+)- or (−)-oxaprotiline applied by the bath wer
Autor:
Nagayama Haruo, Mizobe Yuuko, Yamada Kumiko, Nakamura Makoto, Tsuchiyama Kounosuke, Akiyoshi Jotaro
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 16(3)
1. 1. A possible coupling of the rat cerebral cortex 5-hydroxytryptamine (5HT)-1A receptors to isletactivating protein (IAP, pertussis toxin) sensitive Gi protein was investigated by studying the effects of a guanosine 5′-triphosphate (GTP) and IAP
Autor:
Gary B. Glavin
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 16(2)
1. 1. Rats were prepared with intracerebral cannulas for microinjection of test compounds into various brain regions. 2. 2. Selective dopamine D1 agonists (SKF38393, SKF75670C) and a D1 antagonist (SCH23390) were injected into the cell body regions o
Autor:
Mark J. Majchrzak, Steven C. Dilsaver
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 16(1)
1. Ethanol decreases the release of acetylcholine through effects on presynaptic neurons at both muscarinic and nicotinic junctions. 2. Blockade of the release of acetylcholine should produce denervation supersensitivity at both nuscarinic and nicoti
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 15(2)
1. 1. Wistar rats were implanted with cannulae into the medial preoptic and anterior hypothalamic areas for intracerebral injections. 2. 2. Unilateral intracerebral injections of carbachol (1μg) into a limited area of the basal forebrain decreased s