Zobrazeno 1 - 5
of 5
pro vyhledávání: '"P Cooke"'
Autor:
Jack D Hywood, Colleen Stubbs, Sara Sadeghipour, Jun Yuan, Zoe E. Clayton, John Wong, Sanjay Patel, John P. Cooke
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0255075 (2021)
PLoS ONE, Vol 16, Iss 8 (2021)
PLoS ONE, Vol 16, Iss 8, p e0255075 (2021)
PLoS ONE, Vol 16, Iss 8 (2021)
Induced endothelial cells (iECs) generated from neonatal fibroblasts via transdifferentiation have been shown to have pro-angiogenic properties and are a potential therapy for peripheral arterial disease (PAD). It is unknown if iECs can be generated
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88972 (2014)
PLoS ONE
PLoS ONE
Atherosclerotic disorders are well known to be associated with obesity, lipid profile, smoking, hypertension and other medical comorbidities, and large cohort studies have explored the childhood correlates to these adult risk factors. However, there
Autor:
Jin Yu, Jeffrey B. Velotta, Mei Huang, Andrew S. Lee, Joseph C. Wu, Ngan F. Huang, John P. Cooke, Kitchener D. Wilson, Zongjin Li, Robert C. Robbins
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7040 (2009)
PLoS ONE
PLoS ONE
Background Many patients with ischemic heart disease have cardiovascular risk factors such as cigarette smoking. We tested the effect of nicotine (a key component of cigarette smoking) on the therapeutic effects of human embryonic stem cell-derived e
Autor:
Jacqueline Avis, Janet Dawson, Paul J. Groot-Kormelink, Albert E. Parker, Shifeng Pan, Mark L. Sandberg, Ben G. Wen, Andrew T. Miller, Cynthia Cienfuegos, H. Martin Seidel, Monique Stinson, Daniel R. Beisner, John A. H. Hoerter, Michael P. Cooke, Shin-Shay Tian, Pamela Tranter, Martin Gosling, Christian Schmedt, Mark McPate, Carol Dahlberg
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0131071 (2015)
PLoS ONE, Vol 10, Iss 6, p e0131071 (2015)
Emerging approaches to treat immune disorders target positive regulatory kinases downstream of antigen receptors with small molecule inhibitors. Here we provide evidence for an alternative approach in which inhibition of the negative regulatory inosi
Autor:
Yohannes T. Ghebremariam, John P. Cooke, Andrew J. Patterson, Christine L. C. Johnson, Keisuke Yamada, Rainer H. Böger, Rani Agrawal, Jerry C. Lee, Maike Anderssohn, Dorothee Atzler, John P. Higgins
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e60653 (2013)
PLoS ONE, Vol 8, Iss 4, p e60653 (2013)
Aims Genetic and pharmacological studies have shown that impairment of the nitric oxide (NO) synthase (NOS) pathway is associated with hypertension and insulin-resistance (IR). In addition, inhibition of NOS by the endogenous inhibitor, asymmetric di