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Autor:
Shahira Ghobrial, Stuart S. Kaufman, Alexander Kroemer, Nada Yazigi, Udeme D Ekong, Thomas M. Fishbein, Khalid Khan, Corina E. Gonzalez, J. Hawksworth, Cal S. Matsumoto
Publikováno v:
Pediatric Transplantation. 25
Background Warm-antibody AIHA is known to complicate solid organ (SOT) and HSCT, the disease maybe refractory to standard therapy. Immunosuppressive therapies as well as IVIG, and rituximab have been the main stay of treatment. Over the past decade,
Autor:
Pascal Roland Enok Bonong, Nancy Robitaille, Philip C. Spinella, Suzanne Vercauteren, Marisa Tucci, Victor Lewis, Helen Trottier, Louise Laporte, Chantal Buteau, Caroline Alfieri, Michel Duval, Geoffrey D.E. Cuvelier, Jacques Lacroix
Publikováno v:
Pediatric Transplantation. 25
Background Epstein-Barr virus (EBV) can cause severe disease following hematopoietic stem cell transplant (HSCT), including post-transplant lymphoproliferative disorder (PTLD). The objective was to analyze risk factors associated with post-transplant
Autor:
Jeffery J. Auletta, Kimberly Taylor, Veronika Polishchuk, Dean A. Lee, Rajinder P.S. Bajwa, Rolla Abu-Arja, Mariah Wright, Vinita B. Pai, Hemalatha G. Rangarajan
Publikováno v:
Pediatric Transplantation. 25
Background Immunosuppressive prophylaxis is usually given to decrease the development of acute graft versus host disease (GvHD) after allogeneic hematopoietic stem cell transplantation (HSCT). Belatacept is a Cytotoxic T-lymphocyte-associated protein
Autor:
Sema Anak, Sude Sema Behar, Hülya Bilgen, Leyla Telhan, Kürşat Özdilli, Yöntem Yaman, Murat Elli, Serdar Nepesov, Nihan Bayram
Publikováno v:
Pediatric Transplantation. 25
Introduction (Ph-like) ALL is a subset of leukemia which has a gene expression profile similar to Ph+disease, but without the presence of BCR-ABL1 translocation. Case description We reported an exceptional case of a child with relapsed Ph-like ALL wi
Publikováno v:
Pediatric Transplantation. 25
FA is the most common cause of inherited BMF syndromes. The only cure for BMF in FA remains HSCT. Due to DNA instability in FA, RIC has been used to decrease immediate and late complications of HSCT. Most FA conditioning regimens in mismatched and un
Autor:
Maryam Behfar, Faihaa Hkima Abou Fakher, Hamid Farajifard, Tahani Ali, Maged Kheder, Amir Ali Hamidieh
Publikováno v:
Pediatric Transplantation. 25
IL-10R deficiency results in severe immune dysregulation. Herein, we describe the successful treatment of a girl aged 6.8 years with IL10R deficiency by using RIC prior to HSCT from a matched unrelated donor. The regimen was well tolerated, the engra
Autor:
Junko Takita, Yasuo Kubota, Keita Hogetsu, Katsuyoshi Koh, Shota Kato, Mitsuteru Hiwatari, Kentaro Watanabe, Yuki Arakawa
Publikováno v:
Pediatric Transplantation. 24
The efficacy of tandem HDCT against high-risk neuroblastoma has been reported; however, an optimal regimen remains to be established. In this paper, we report our experience using tandem HDCT comprising the MEC and BuMel regimens in patients with hig
Autor:
Kenji Kishimoto, Atsuro Saito, Sayaka Nakamura, Toshiaki Ishida, Shoji Fukushima, Nobuyuki Yamamoto, Daiichiro Hasegawa, Akira Okada, Akihiro Tamura, Aiko Kozaki, Yoshiyuki Kosaka, Kei Irie
Publikováno v:
Pediatric Transplantation. 24
This prospective observational study analyzed the pharmacokinetics of busulfan in Japanese children and evaluated the predicting accuracy of previous pediatric PPK models of busulfan. This study enrolled five patients (aged 2-12 years, BW 14-48 kg) r
Autor:
Alaa Elhaddad, Mahmoud Hammad, Hanafy Hafez, Lama Elhalaby, Dina Yassin, Nayera Hamdy, Omayma Hassanain, Amr Abdallah, Sherine Salem
Publikováno v:
Pediatric Transplantation. 24
Background/objectives Despite the apparent efficacy and favorable toxicity profile of TKIs, allogeneic SCT remains the only curative treatment for CML especially in younger patients, but TRM should be considered. We evaluated the clinical outcomes of
Autor:
Jin Kyung Suh, Dae Yeon Kim, Jong Jin Seo, Young Sun Kim, Ho Joon Im, Jong Jin Lee, So Yoon Min, Kyung-Nam Koh, Seung Do Ahn, Hyery Kim, Jung-Man Namgoong
Publikováno v:
Pediatric Transplantation. 24
This study was performed to evaluate the safety and effectiveness of tandem HDCT/ASCT combined with targeted radiotherapy using 131 I-MIBG for high-risk neuroblastoma. Patients with high-risk neuroblastoma were treated with 8 to 10 cycles of inductio